Tunnels for protein export from the endoplasmic reticulum
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- dc.contributor.author Raote, Ishier
- dc.contributor.author Malhotra, Vivek
- dc.date.accessioned 2021-05-10T11:38:35Z
- dc.date.issued 2021
- dc.description.abstract The functions of coat protein complex II (COPII) coats in cargo packaging and the creation of vesicles at the endoplasmic reticulum are conserved in eukaryotic protein secretion. Standard COPII vesicles, however, cannot handle the secretion of metazoan-specific cargoes such as procollagens, apolipoproteins, and mucins. Metazoans have thus evolved modules centered on proteins like TANGO1 (transport and Golgi organization 1) to engage COPII coats and early secretory pathway membranes to engineer a novel mode of cargo export at the endoplasmic reticulum.
- dc.description.sponsorship Financial support from: Ministerio de Economía y Competitividad (SEV-2012-0208, BFU2013-44188-P, and CSD2009-00016 to V.M. and IJCI-2017-34751 to I.R.)
- dc.format.mimetype application/pdf
- dc.identifier.citation Raote I, Malhotra V. Tunnels for protein export from the endoplasmic reticulum. Annu Rev Biochem. 2021;90:605-30. DOI: 10.1146/annurev-biochem-080120-022017
- dc.identifier.doi http://dx.doi.org/10.1146/annurev-biochem-080120-022017
- dc.identifier.issn 0066-4154
- dc.identifier.uri http://hdl.handle.net/10230/47377
- dc.language.iso eng
- dc.publisher Annual Reviews Inc
- dc.relation.ispartof Annu Rev Biochem. 2021;90:605-30
- dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/CSD2009-00016
- dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/BFU2013-44188-P
- dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/IJCI-2017-34751
- dc.rights © Annual Reviews. Posted, with permission, from the Annual Review of Biochemistry, 2021;90:605-30.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.subject.other Proteïnes
- dc.subject.other Reticle endoplasmàtic
- dc.title Tunnels for protein export from the endoplasmic reticulum
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/acceptedVersion