Geometric diagrams of genomes: constructing a visual grammar for 3D genomics
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- dc.contributor.author Molins-Pitarch, Carla
- dc.contributor.author Khao, Jonathan
- dc.contributor.author Bonet, Santiago
- dc.contributor.author Justicia, Yolanda
- dc.contributor.author Altube, Clementina
- dc.contributor.author Goodstadt, Mike N.
- dc.contributor.author Ribot, Francesc
- dc.contributor.author Lieberman Aiden, Erez
- dc.contributor.author Neretti, Nicola
- dc.contributor.author McGill, Gaël G.
- dc.contributor.author Marti-Renom, Marc A.
- dc.date.accessioned 2025-10-09T05:48:24Z
- dc.date.available 2025-10-09T05:48:24Z
- dc.date.issued 2025
- dc.description.abstract Advances in the field of three-dimensional (3D) genomics have revealed an ever-expanding array of architectural features that were unknown only a few years ago. Just as ribbon diagrams integrate spatial and symbolic representation to communicate the shape of a protein, the representation of genomes in 3D space requires the development and use of new cartographic symbols and visual conventions. Here, we propose a conceptualized grammar that makes it easier to create visual 3D representations of genomes.
- dc.description.sponsorship This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Sklodowska-Curie grant agreement No 823327 to M.A.M-R. and F.R. M.A.M-R. also acknowledges support by the Spanish Ministerio de Ciencia e Innovación (PID2020-115696RB-I00 and PID2023-151484NB-I00). M.A.M-R., E.L.A., and N.N. acknowledge support by the National Human Genome Research Institute of the National Institutes of Health under Award Number RM1HG011016. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
- dc.format.mimetype application/pdf
- dc.identifier.citation Molins-Pitarch C, Khao J, Bonet S, Justicia Y, Altube C, Goodstadt M, et al. Geometric diagrams of genomes: constructing a visual grammar for 3D genomics. Genome Biol. 2025 Jun 26;26(1):181. DOI: 10.1186/s13059-025-03646-y
- dc.identifier.doi http://dx.doi.org/10.1186/s13059-025-03646-y
- dc.identifier.issn 1474-7596
- dc.identifier.uri http://hdl.handle.net/10230/71440
- dc.language.iso eng
- dc.publisher BioMed Central
- dc.relation.ispartof Genome biology. 2025 Jun 26;26(1):181
- dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/PID2020-115696RB-I00
- dc.relation.projectID info:eu-repo/grantAgreement/ES/3PE/PID2023-151484NB-I00
- dc.rights © The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.other Genòmica
- dc.title Geometric diagrams of genomes: constructing a visual grammar for 3D genomics
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion