Normative data for impact microindentation for Australian men: cross-sectional data from the geelong osteoporosis study

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  • dc.contributor.author Rufus-Membere, Pamela
  • dc.contributor.author Holloway-Kew, Kara L.
  • dc.contributor.author Kotowicz, Mark A.
  • dc.contributor.author Diez-Perez, Adolfo
  • dc.contributor.author Pasco, Julie A.
  • dc.date.accessioned 2021-10-07T07:51:28Z
  • dc.date.available 2021-10-07T07:51:28Z
  • dc.date.issued 2020
  • dc.description.abstract Impact microindentation (IMI) is a novel technique for assessing the bone material strength index (BMSi) in vivo. However, no studies have presented normative data for BMSi. The aim of this study was to develop such normative data using a population-based sample of men, randomly selected from electoral rolls for the Barwon Statistical Division in southeastern Australia to participate in the Geelong Osteoporosis Study. BMSi was measured on the tibial plateau using an OsteoProbe in 405 men (ages 33 to 96 years) during the period 2016 to 2019. Associations between BMSi, age, and anthropometry were examined using linear regression models. BMSi values ranged from 49.0 to 100.5. BMSi was negatively correlated with age (r = -0.152, p = 0.002), weight (r = -0.103, p = 0.039), and BMI (r = -0.187, p < 0.001), and positively correlated with height (r = +0.107, p = 0.032). Mean ± SD BMSi was 82.6 ± 7.0 for the whole group, and ranged from 85.6 ± 6.0 for ages 30 to 39 years to 79.8 ± 6.6 for ages 80+ years. This study provides normative data that can be used to calculate T- and Z-scores for BMSi. These data will be useful for identifying men with low BMSi. Further research is warranted to derive optimal cut points for BMSi that discriminate fracture risk. © 2020 The Authors. JBMR Plus published by Wiley Periodicals LLC. on behalf of American Society for Bone and Mineral Research.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Rufus-Membere P, Holloway-Kew KL, Kotowicz MA, Diez-Perez A, Pasco JA. Normative data for impact microindentation for Australian men: cross-sectional data from the geelong osteoporosis study. JBMR Plus. 2020 Jul 18; 4(9):e10384. DOI: 10.1002/jbm4.10384
  • dc.identifier.doi http://dx.doi.org/10.1002/jbm4.10384
  • dc.identifier.issn 2473-4039
  • dc.identifier.uri http://hdl.handle.net/10230/48585
  • dc.language.iso eng
  • dc.publisher Wiley
  • dc.relation.ispartof Journal Bone and Mineral Research Plus. 2020 Jul 18; 4(9):e10384
  • dc.rights Copyright © 2020 The Authors. JBMR Plus published by Wiley Periodicals LLC. on behalf of American Society for Bone and Mineral Research. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.subject.keyword Bone material strenght index
  • dc.subject.keyword Impact microindentation
  • dc.subject.keyword Normative data
  • dc.subject.keyword Osteoporosis
  • dc.subject.keyword Population-based
  • dc.title Normative data for impact microindentation for Australian men: cross-sectional data from the geelong osteoporosis study
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion