New perspectives in the management of small cell lung cancer

Pangua, Cristina; Rogado, Jacobo; Serrano-Montero, Gloria; Belda, José; Álvarez Rodríguez, Beatriz; Torrado, Laura; Rodríguez de Dios, Núria; Mielgo-Rubio, Xabier; Trujillo-Reyes, Juan Carlos; Couñago, Felipe

doi:http://dx.doi.org/10.5306/wjco.v13.i6.429

New perspectives in the management of small cell lung cancer

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Pangua C, Rogado J, Serrano-Montero G, Belda-Sanchís J, Álvarez Rodríguez B, Torrado L, Rodríguez De Dios N, Mielgo-Rubio X, Trujillo JC, Couñago F. New perspectives in the management of small cell lung cancer. World J Clin Oncol. 2022 Jun 24;13(6):429-47. DOI: 10.5306/wjco.v13.i6.429

Abstract

The treatment of small cell lung cancer (SCLC) is a challenge for all specialists involved. New treatments have been added to the therapeutic armamentarium in recent months, but efforts must continue to improve both survival and quality of life. Advances in surgery and radiotherapy have resulted in prolonged survival times and fewer complications, while more careful patient selection has led to increased staging accuracy. Developments in the field of systemic therapy have resulted in changes to clinical guidelines and the management of patients with advanced disease, mainly with the introduction of immunotherapy. In this article, we describe recent improvements in the management of patients with SCLC, review current treatments, and discuss future lines of research.