Predicting the template sequence used in CRISPR experiments

Escobosa Olmo, Marc

Predicting the template sequence used in CRISPR experiments

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Citation

Escobosa Olmo, M. Predicting the template sequence used in CRISPR experiments. 2022. handle: http://hdl.handle.net/10230/55086

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Abstract

I participated in developing the CRISPR-A tool, the first NGS-based method for gene-editing assessment, and created three Random Forest models each specialising in predicting the modification made in CRISPR experiments that are deletions, insertions or substitutions without having the template sequence available.