Benvinguts al Repositori Digital de la UPF

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per data de publicació

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per data de publicació

Ordena per: Ordre: Resultats:

  • Fickett, James W.; Guigó Serra, Roderic (Oxford University Press, 1993)
    A number of experimental methods have been reported for estimating the number of genes in a genome, or the closely related coding density of a genome, defined as the fraction of base pairs in codons. Recently, DNA sequence ...
  • Granja, Ricardo; Fernández-Fernández, José Manuel, 1967-; Izaguirre, Victor; González García, Carmen; Ceña, Valentin (Elsevier, 1995)
    We have studied the contribution of P-type voltage-dependent Ca2+ channels to both catacholamine (CA) and ATP secretion from bovine chromaffin cells induced by high K+ or nicotine using omega-agatoxin IVA, a selective ...
  • Guigó Serra, Roderic (Centre de Supercomputació de Catalunya, 1995)
  • Izaguirre, Victor; Fernández-Fernández, José Manuel, 1967-; Ceña, Valentin; González García, Carmen (Elsevier, 1997)
    Nicotine-induced ATP secretion from chromaffin cells was blocked by imipramine and desipramine. This blocking action took place on both, fast and slow, components of ATP secretion. Exposure of chromaffin cells to nicotine ...
  • Matthes, Hans W. D.; Smadja, C.; Valverde Granados, Olga; Vonesch, J. L.; Foutz, A. S.; Boudinot, E.; Denavit-Saubié, M.; Severini, Cintia; Negri, Lucia; Roques, Bernard P.; Maldonado, Rafael, 1961-; Kieffer, Brigitte L. (Society for Neuroscience, 1998)
    Previous pharmacological studies have indicated the possible existence of functional interactions between μ-, δ- and κ-opioid receptors in the CNS. We have investigated this issue using a genetic approach. Here we describe ...
  • Álvarez, Alejandra R.; Alarcón Martínez, Rodrigo; Opazo, Carlos; Campos, Eliseo O.; Muñoz López, Francisco José, 1964-; Calderón, Frances H.; Dajas, Federico; Gentry, Mary K.; Doctor, Bhupendra P.; Mello, Fernando G. de; Inestrosa, Nibaldo C. (Society for Neuroscience, 1998)
    Brain acetylcholinesterase (AChE) forms stable complexes with amyloid-beta peptide (Abeta) during its assembly into filaments, in agreement with its colocalization with the Abeta deposits of Alzheimer's brain. The association ...
  • Semir, Vladimir de, 1948-; Ribas, Cristina; Revuelta, Gemma (American Medical Association, 1998)
    CONTEXT: Scientific journals issue press releases to disseminate scientific news about articles they publish. OBJECTIVE: To assess whether press releases about journal articles were associated with publication of subsequent ...
  • Guigó Serra, Roderic (Mary Ann Liebert, Inc, 1998)
    In a number of programs for gene structure prediction in higher eukaryotic genomic sequences, exon prediction is decoupled from gene assembly: a large pool of candidate exons is predicted and scored from features located ...
  • Chow, Alan; Erisir, A.; Farb, C.; Nadal, M. S.; Ozaita Mintegui, Andrés, 1969-; Lau, David; Welker, E.; Rudy, Bernardo (Society for Neuroscience, 1999)
    Kv3.1 and Kv3.2 K+ channel proteins form similar voltage-gated K+ channels with unusual properties, including fast activation at voltages positive to −10 mV and very fast deactivation rates. These properties are thought ...
  • Valjent, Emmanuel; Corvol, Jean-Christophe; Pagès, Christiane; Besson, Marie-J.; Maldonado, Rafael, 1961-; Caboche, Jocelyne (Society for Neuroscience, 2000)
    A central feature of drugs of abuse is to induce gene expression in discrete brain structures that are critically involved in behavioral responses related to addictive processes. Although extracellular signal-regulated ...
  • Eyras Jiménez, Eduardo; Lozano, Yolanda (Elsevier, 2000)
    We construct the effective action of certain exotic branes in the Type II theories which are not predicted by their space-time supersymmetry algebras. We analyze in detail the case of the NS-7B brane, S-dual to the D7-brane, ...
  • Guigó Serra, Roderic; Agarwal, Pankaj; Abril Ferrando, Josep Francesc; Burset Albareda, Moisès; Fickett, James W. (Cold Spring Harbor Laboratory Press-CSHL Press, 2000)
    One of the first useful products from the human genome will be a set of predicted genes. Besides its intrinsic scientific interest, the accuracy and completeness of this data set is of considerable importance for human ...
  • Thomson, Timothy M.; Lozano, Juan José; Loukili, Noureddine; Carrió, Roberto; Serras Rigalt, Florenci; Cormand, Bru; Valeri, Marta; Díaz, Víctor M.; Abril Ferrando, Josep Francesc; Burset Albareda, Moisès; Merino, Jesús; Macaya, Alfons; Corominas Guiu, Montserrat; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2000)
    UEV proteins are enzymatically inactive variants of the E2 ubiquitin-conjugating enzymes that regulate noncanonical elongation of ubiquitin chains. In Saccharomyces cerevisiae, UEV is part of the RAD6-mediated error-free ...
  • Haley, Jane E.; Abogadie, Fe C.; Fernández-Fernández, José Manuel, 1967-; Dayrell, Mariza; Vallis, Yvonne; Buckley, Noel J.; Brown, David A. (Society for Neuroscience, 2000)
    Rat superior cervical ganglion (SCG) neurons express low-threshold noninactivating M-type potassium channels (I-K(M)), which can be inhibited by activation of M-1 muscarinic receptors (M-1 mAChR) and bradykinin (BK) B-2 ...
  • Lau, David; Vega-Saenz de Miera, Eleazar; Contreras, Diego; Ozaita Mintegui, Andrés, 1969-; Harvey, Michael; Chow, Alan; Noebels, Jeffrey L.; Paylor, Richard; Morgan, James I.; Leonard, Christopher S.; Rudy, Bernardo (Society for Neuroscience, 2000)
    Voltage-gated K+ channels of the Kv3 subfamily have unusual electrophysiological properties, including activation at very depolarized voltages (positive to −10 mV) and very fast deactivation rates, suggesting special roles ...
  • Valverde Granados, Olga; Maldonado, Rafael, 1961-; Valjent, Emmanuel; Zimmer, Anne M.; Zimmer, Andreas (Society for Neuroscience, 2000)
    The functional interactions between the endogenous cannabinoid and opioid systems were evaluated in pre-proenkephalin-deficient mice. Antinociception induced in the tail-immersion test by acute Delta9-tetrahydrocannabinol ...
  • Parra Farré, Genís; Blanco, Enrique; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2000)
    GeneID is a program to predict genes in anonymous genomic sequences designed with a hierarchical structure. In the first step, splice sites, and start and stop codons are predicted and scored along the sequence using ...
  • Guigó Serra, Roderic (Institut d'Estudis Catalans, 2000)
  • Zimmer, Andreas; Valjent, Emmanuel; König, Monika; Zimmer, Anne M.; Robledo, Patrícia, 1958-; Hahn, Heidi; Valverde Granados, Olga; Maldonado, Rafael, 1961- (Society for Neuroscience, 2001)
    The involvement of dynorphin on Delta-9-tetrahydrocannabinol (THC) and morphine responses has been investigated by using mice with a targeted inactivation of the prodynorphin (Pdyn) gene. Dynorphin-deficient mice show ...
  • Kalaydjieva, Luba; Gresham, David; Calafell i Majó, Francesc (BioMed Central, 2001)
    Background: Data provided by the social sciences as well as genetic research suggest that the 8-10 million Roma (Gypsies) who live in Europe today are best described as a conglomerate of genetically isolated founder ...