Documents de recerca, en accés obert, com ara articles de revista, llibres, comunicacions, ponències o posters a jornades i congressos, etc., del Departament de Ciències Experimentals i de la Salut de la UPF.
Bousquet, Jean; Antó i Boqué, Josep Maria; Zuberbier, Torsten(Elsevier, 2022)
Drug repurposing is a major field of value-added medicine. It involves investigating and evaluating existing drugs for new therapeutic purposes that address unmet healthcare needs. Several unmet needs in allergic rhinitis ...
Vieira, Rafael José; Antó i Boqué, Josep Maria; MASK study group(Elsevier, 2022)
Background: Several studies have suggested an impact of allergic rhinitis on academic productivity. However, large studies with real-world data (RWD) are not available. Objective: To use RWD to assess the impact of allergic ...
Akin, Leyla; Pérez Jurado, Luis Alberto; Dattani, Mehul T.(Elsevier, 2022)
Purpose: We aimed to investigate the molecular basis underlying a novel phenotype including hypopituitarism associated with primary ovarian insufficiency. Methods: We used next-generation sequencing to identify variants ...
Critical Assessment of Structure Prediction (CASP) is an organization aimed at advancing the state of the art in computing protein structure from sequence. In the spring of 2020, CASP launched a community project to compute ...
Nierenberg, Andrew A.; Alonso Caballero, Jordi; WHO World Mental Health Survey collaborators(Wiley, 2021)
Objectives: To examine patterns and predictors of perceived treatment helpfulness for mania/hypomania and associated depression in the WHO World Mental Health Surveys. Methods: Face-to-face interviews with community samples ...
We evaluated interleukin-6 (IL-6) receptor-α subunit (IL-6Rα) signaling inhibition with sarilumab and tocilizumab, the association between IL-6Rα receptor occupancy (RO) and C-reactive protein (CRP), and the potential ...
Khreis, Haneen; Sanchez, Kristen A.; Foster, Margaret; Burns, Jacob; Nieuwenhuijsen, Mark J.; Jaikumar, Rohit; Ramani, Tara; Zietsman, Josias(Elsevier, 2023)
Background: Urban areas are hot spots for human exposure to air pollution, which originates in large part from traffic. As the urban population continues to grow, a greater number of people risk exposure to traffic-related ...
Couto-Silva, Cainã M.; Nunes, Kelly; Venturini, Gabriela; Castro e Silva, Marcos Araújo; Pereira, Lygia V.; Comas, David, 1969-; Pereira, Alexandre C.; Hünemeier, Tábita(American Association for the Advancement of Science (AAAS), 2023)
Ecological conditions in the Amazon rainforests are historically favorable for the transmission of numerous tropical diseases, especially vector-borne diseases. The high diversity of pathogens likely contributes to the ...
Vigo, Daniel V.; Alonso Caballero, Jordi; Kessler, Ronald C.(Cambridge University Press, 2020)
Background: Major depressive disorder (MDD) is a leading cause of morbidity and mortality. Shortfalls in treatment quantity and quality are well-established, but the specific gaps in pharmacotherapy and psychotherapy are ...
Husky, Mathilde M.; Sadikova, Ekaterina; Lee, Sue; Alonso Caballero, Jordi; Auerbach, Randy P.; Bantjes, Jason; Bruffaerts, Ronny; Cuijpers, Pim; Ebert, David Daniel; Gutiérrez Garcia, Raùl; Hasking, Penelope; Mak, Arthur; McLafferty, Margaret; Sampson, Nancy A.; Stein, Dan J.; Kessler, Ronald C.; WHO WMH‐ICS Collaborators(Cambridge University Press, 2022)
Background: This study investigates associations of several dimensions of childhood adversities (CAs) with lifetime mental disorders, 12-month disorder persistence, and impairment among incoming college students. Methods: ...
Cavaco, Marco; Frutos, Silvia; Oliete, Paula; Valle, Javier; Andreu Martínez, David; Castanho, Miguel A.R.B.; Vila-Perelló, Miquel; Neves, Vera(American Chemical Society (ACS), 2021)
The frequency of brain disease has increased significantly in the past years. After diagnosis, therapeutic options are usually limited, which demands the development of innovative therapeutic strategies. The use of ...
Somatic genetic variants have been studied for several years mostly concerning cancer, where they contribute to its origin and development. It is also clear that the somatic variants load is greater in aged individuals in ...
Background: Benzophenone-3 (BP-3) and its major metabolite benzophenone-1 (BP-1) are widely used as UV filters in sunscreens and cosmetics to prevent sunburn and skin damage, or as stabilizers to prevent photodegradation ...
Childhood obesity is a relevant public health problem. The school food environment has been identified as an important factor for promoting healthy eating behaviors. This study assessed the availability of and proximity ...
SDR (Short-chain Dehydrogenases/Reductases) are one of the oldest and heterogeneous superfamily of proteins, whose classification is problematic because of the low percent identity, even within families. To get clearer ...
(1) Background: Patients with advanced chronic liver disease (ACLD) are living longer with more comorbidities because of improved medical and surgical management. However, patients with ACLD are at increased risk of ...
Vázquez, Susana; Pascual, Julio (Pascual Santos); Durán-Jordà, Xavier; Hernández, Jose Luís; Crespo, Marta; Oliveras, Anna(MDPI, 2023)
Preeclampsia (PE) is characterized by the new onset of hypertension (HT) and proteinuria beyond the 20th week of gestation. We aimed to find the best predictor of PE and find out if it is different in women with or without ...
Pérez-Martín, Hipólito; Lidón-Moyano, Cristina; González-Marrón, Adrián; Fu, Marcela; Pérez-Ortuño, Raúl; Ballbè, Montse; Martín-Sánchez, Juan Carlos; Pascual Esteban, José A.; Fernández, Esteve; Martínez-Sánchez, Jose M.(MDPI, 2023)
This study aims to describe the nicotine metabolite ratio among tobacco smokers and electronic cigarette (e-cigarette) users and nonusers. We analyzed pooled data from a longitudinal and a cross-sectional study of the adult ...
In this manuscript we studied the relationship between WMH and biological age (B-age) in patients with acute stroke. We included in this study 247 patients with acute stroke recruited at Hospital del Mar having both ...
Changes in the communication ecosystem have generated profound transformations in current science communication. In the same way, the coexistence of diverse actors with different objectives and professional standards also ...