The Barcelona Institute for Global Health, ISGlobal, is the fruit of an innovative alliance between the "la Caixa" Foundation", academic institutions and government bodies to contribute to the efforts undertaken by the international community to address the challenges in global health. In 2016, the Centre for Research in Environmental Epidemiology (CREAL), the Barcelona Centre for International Health Research (CRESIB) and the Barcelona Institute for Global Health (ISGlobal) completed a successful merging process. As a result, today ISGlobal is a cutting-edge institution with capacity to address global health challenges trough research, translation and education.