Browsing by Author "Serrano Pubull, Luis"

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  • Güell Cargol, Marc (Universitat Pompeu Fabra, 2011-04-12)
    With only 689 genes Mycoplasma pneumoniae (M. pneumoniae) is among the simplest known organisms. Because of this simplicity, mycoplasma represents an attractive organism for systems-wide analyses. Such approaches aiming ...
  • Cianferoni, Damiano (Universitat Pompeu Fabra, 2023-10-17)
    Aquesta tesi presenta diversos avenços que inclouen: (i) noves funcionalitats afegides a la “suite” d'eines de disseny de proteïnes FoldX per permetre als usuaris treballar amb qualsevol tipus de molècula; (ii) estudis ...
  • Gallo López, Carolina (Universitat Pompeu Fabra, 2018-12-20)
    Understanding how the growth rate is regulated in bacteria is an ongoing challenge in biology and its controlled regulation would have a great impact in the biotechnological industry. Growth rates may be regulated by several ...
  • Miravet Verde, Samuel (2021-05-28)
    Small proteins (SEPs; <100aa) are involved in essential processes such as cell homeostasis, signalling, or metabolism. However, they have been overlooked because of computational and experimental difficulties that prevent ...
  • Montero-Blay, Ariadna (Universitat Pompeu Fabra, 2023-02-17)
    Els Micoplasmes són un grup de bacteris caracteritzats per tenir genomes mínims, capacitats biosintètiques limitades i una xarxa metabòlica simplificada. Aquesta tesi explora com diferents espècies de Micoplasma poden ser ...
  • Lloréns Rico, Verónica (Universitat Pompeu Fabra, 2018-01-11)
    One of the major challenges of biology is to understand how entire cells or organisms behave in homeostasis and in response to perturbations. Whole-cell modeling promotes this understanding by integrating different cellular ...
  • Benisty, Hannah (Universitat Pompeu Fabra, 2020-01-07)
    The RAS oncogenes KRAS, NRAS and HRAS are mutated in one third of human cancers where they exhibit different mutation patterns. A potential factor contributing to this mutation bias is the variation of RAS expression ...
  • Shaw, Daniel (Universitat Pompeu Fabra, 2020-01-13)
    Understanding what constitutes a true Minimal Cell is a key challenge in synthetic biology. In this work, we present two new tools to aid in this endeavour. i) A novel methodology for minimising the Mycoplasma pneumoniae ...
  • Campagna, Anne (Universitat Pompeu Fabra, 2012-09-19)
    Interactions between proteins give rise to many functions in cells. In the lastdecade, highthroughput experiments have identified thousands of protein interactions, which are often represented together as large protein ...
  • Trussart, Marie (Universitat Pompeu Fabra, 2018-05-15)
    Des de l’aparició de les tecnologies de seqüenciació d’alt rendiment, els conjunts de dades biològiques han esdevingut cada cop més grans i complexes, la qual cosa els fa pràcticament impossibles d’interpretar manualment. ...
  • Paetzold, Bernhard (Universitat Pompeu Fabra, 2016-06-16)
    M. pneumoniae is one of the smallest self-replicating organisms. Many organism wide studies have been performed on M. pneumoniae and provide a wealth of information on the bacteria. However, the genetic tools to manipulate ...
  • Ciampi, Ludovica (Universitat Pompeu Fabra, 2023-05-03)
    The nervous system comprises an immense number of cells that serve highly specialized roles. Accordingly, they possess unique morphological and functional attributes, greatly shaped by specific Alternative Splicing (AS) ...
  • Hernandez Alias, Xavier (Universitat Pompeu Fabra, 2023-02-28)
    Malgrat teixits diferents presenten diferències en l'ús de codons i en els repertoris d'anticodons dels ARNt, el coneixement sobre la co-adaptació entre codó-anticodó en eucariotes multicel·lulars és incomplet. D'una banda, ...

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