Browsing by Subject "G-protein coupled receptors"

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  • Gallo, María, 1989- (2021-07-22)
    This thesis focuses on one of the biggest challenges facing drug discovery field: the efficient targeted delivery of therapeutic compounds, and how cell-penetrating peptides (CPPs) acting as drug delivery vectors can ...
  • Ferruz Capapey, Noelia 1988-; Doerr, Stefan, 1987-; Vanase Frawley, Michelle A.; Zou, Yaozhong; Chen, Xiaomin; Marr, Eric S.; Nelson, Robin T.; Kormos, Bethany L.; Wager, Travis T.; Hou, Xinjun J.; Villalobos, Anabella; Sciabola, Simone; De Fabritiis, Gianni (Nature Publishing Group, 2018)
    The recent increase in the number of X-ray crystal structures of G-protein coupled receptors (GPCRs) has been enabling for structure-based drug design (SBDD) efforts. These structures have revealed that GPCRs are highly ...