Browsing by Author "Villoslada, Pablo"

Sort by: Order: Results:

  • Burden of neurological diseases in the US revealed by web searches
    Baeza Yates, Ricardo; Mohan Sangal, Puneet; Villoslada, Pablo (Public Library of Science (PLoS), 2017)
    Background: Analyzing the disease-related web searches of Internet users provides insight into the interests of the general population as well as the healthcare industry, which can be used to shape health care policies. Methods: ...
  • Dynamic cross-regulation of antigen-specific effector and regulatory T cell subpopulations and microglia in brain autoimmunity
    Martínez Pasamar, Sara; Abad Adan, Elena; Moreno, Beatriz; Vélez de Mendizábal, Nieves; Martínez Forero, Ivan; García Ojalvo, Jordi; Villoslada, Pablo (BioMed Central, 2013)
    Background: Multiple Sclerosis (MS) is considered a T-cell-mediated autoimmune disease with a prototypical oscillatory behavior, as evidenced by the presence of clinical relapses. Understanding the dynamics of immune cells ...
  • Dynamics and heterogeneity of brain damage in multiple sclerosis
    Kotelnikova, Ekaterina; Kiani, Narsis A.; Abad Adan, Elena; Martínez Lapiscina, Elena H.; Andorrà, Magí; Zubizarreta, Irati; Pulido Valdeolivas, Irene; Pertsovskaya, Inna; Alexopoulos, Leonidas G.; Olsson, Tomas; Martin, Roland; Paul, Friedemann; Tegnér, Jesper; García Ojalvo, Jordi; Villoslada, Pablo (Public Library of Science (PLoS), 2017)
    Multiple Sclerosis (MS) is an autoimmune disease driving inflammatory and degenerative processes that damage the central nervous system (CNS). However, it is not well understood how these events interact and evolve to evoke ...
  • Dynamics and predictors of cognitive impairment along the disease course in multiple sclerosis
    López-Soley, Elisabet; Martínez-Heras, Eloy; Andorrà, Magí; Solanes, Aleix; Radua, Joaquim; Montejo, Carmen; Alba-Arbalat, Salut; Solà-Valls, Núria; Pulido Valdeolivas, Irene; Sepúlveda, Maria; Romero-Pinel, Lucía; Munteis Olivas, Elvira; Martínez-Rodriguez, José E.; Blanco, Yolanda; Martínez Lapiscina, Elena H.; Villoslada, Pablo; Saiz, Albert; Solana, Elisabeth; Llufriu, Sara (MDPI, 2021)
    Background: the evolution and predictors of cognitive impairment (CI) in multiple sclerosis (MS) are poorly understood. We aimed to define the temporal dynamics of cognition throughout the disease course and identify ...
  • Genome-wide analysis of wild-type epstein-barr virus genomes derived from healthy individuals of the 1000 genomes project
    Santpere Baró, Gabriel, 1981-; Darre, Fleur; Blanco, Soledad; Alcami, Antonio; Villoslada, Pablo; Albà Soler, Mar; Navarro i Cuartiellas, Arcadi, 1969- (Oxford University Press, 2014)
    Most people in the world (∼90%) are infected by the Epstein–Barr virus (EBV), which establishes itself permanently in B cells. Infection by EBV is related to a number of diseases including infectious mononucleosis, multiple ...
  • Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in multiple sclerosis
    Vélez de Mendizábal, Nieves; Carneiro, Jorge; Solé Vicente, Ricard, 1962-; Goñi, Joaquín; Bragard, Jean; Martínez Forero, Ivan; Martínez Pasamar, Sara; Sepulcre, Jorge; Torrealdea, Javier; Bagnato, Francesca; García Ojalvo, Jordi; Villoslada, Pablo (BioMed Central, 2011)
    Background: The relapsing-remitting dynamics is a hallmark of autoimmune diseases such as Multiple Sclerosis (MS). Although current understanding of both cellular and molecular mechanisms involved in the pathogenesis of ...
  • Multiscale behavior in living systems
    Kennedy, Keith Endres (Universitat Pompeu Fabra, 2023-06-27)
    This thesis focuses on the multiscale nature of the biological process that underpin the function of all living systems. A first project centers on the disease known as multiple sclerosis, and utilizes various datasets at ...
  • Transient oscillatory dynamics of interferon beta signaling in macrophages
    Pertsovskaya, Inna; Abad Adan, Elena; Domedel Puig, Núria; García Ojalvo, Jordi; Villoslada, Pablo (BioMed Central, 2013)
    Background: Interferon-beta (IFN-beta) activates the immune response through the type I IFN signaling pathway. IFN-beta is important in the response to pathogen infections and is used as a therapy for Multiple Sclerosis. ...