Browsing by Author "Toledo, Estefania"

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  • A Mediterranean diet supplemented with extra virgin olive oil or nuts improves endothelial markers involved in blood pressure control in hypertensive women
    Storniolo, Carolina Emilia; Casillas, Rosario; Bulló, Mònica; Castañer, Olga; Ros, Emilio; Sáez, Guillermo; Toledo, Estefania; Estruch, Ramón; Ruiz-Gutiérrez, Valentina; Fitó Colomer, Montserrat; Martínez-González, Miguel A.; Salas-Salvadó, Jordi; Mitjavila, María Teresa; Moreno, Juan José (Springer, 2017)
    PURPOSE: Serum nitric oxide (NO) reduction and increased endothelin-1 (ET-1) play a pivotal role in endothelial dysfunction and hypertension. Considering that traditional Mediterranean diet (TMD) reduces blood pressure ...
  • Advances in integrating traditional and omic biomarkers when analyzing the effects of the mediterranean diet intervention in cardiovascular prevention.
    Fitó Colomer, Montserrat; Melander, Olle; Martínez, José Alfredo; Toledo, Estefania; Carpéné, Christian; Corella, Dolores (MDPI, 2016)
    Intervention with Mediterranean diet (MedDiet) has provided a high level of evidence in primary prevention of cardiovascular events. Besides enhancing protection from classical risk factors, an improvement has also been ...
  • Association between polyphenol intake and gastric cancer risk by anatomic and histologic subtypes: MCC-Spain
    Rubín-García, María; Vitelli Storelli, Facundo; Molina, Antonio J.; Zamora-Ros, Raúl; Aragonés, Núria; Ardanaz Aicua, Eva; Castaño Vinyals, Gemma; Obón-Santacana Mireia; Gómez-Acebo, Inés; Molina-Barceló, Ana; Fernández-Tardón, Guillermo; Jiménez-Moleón, José Juan; Alguacil Ojeda, Juan; Chirlaque, María Dolores; Toledo, Estefania; Pérez-Gómez, Beatriz; Pollan, Marina; Kogevinas, Manolis; Martín, Vicente (MDPI, 2020)
    Several anticancer properties have been largely attributed to phenolics in in vivo and in vitro studies, but epidemiologic evidence is still scarce. Furthermore, some classes have not been studied in relation to gastric ...
  • Association between the 2018 WCRF/AICR and the low-risk lifestyle scores with colorectal cancer risk in the Predimed Study
    Barrubés, Laura; Babio, Nancy; Hernández-Alonso, Pablo; Toledo, Estefania; Estruch, Ramón; Ros, Emilio; Fitó Colomer, Montserrat; Alonso-Gómez, Ángel; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Pintó Sala, Xavier; Ruiz-Canela, Miguel; Corella, Dolores; Castañer, Olga; Macías-González, Manuel; Salas-Salvadó, Jordi (MDPI, 2020)
    Limited longitudinal studies have been conducted to evaluate colorectal cancer (CRC) incidence based on the updated 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) recommendations or other ...
  • Caffeinated coffee consumption and risk of atrial fibrillation in two Spanish cohorts
    Bazal, P.; Gea, Alfredo; Navarro, A. M.; Salas Salvadó, Jordi; Corella, Dolores; Alonso-Gómez, Ángel; Fitó Colomer, Montserrat; Muñoz-Bravo, Carlos; Estruch, Ramón; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Ros, Emilio; Rekondo, Javier; Muñoz, Miguel Ángel; Basora, Josep; Sorlí, José Vicente; Toledo, Estefania; Martínez-González, Miguel A.; Ruiz-Canela, Miguel (Oxford University Press, 2021)
    Aims: The association between caffeinated coffee consumption and atrial fibrillation remains unclear. Recent studies suggest an inverse association only between a moderate caffeinated coffee consumption and atrial fibrillation, ...
  • Diastolic dysfunction and exercise capacity in patients with metabolic syndrome and overweight/obesity
    Alonso-Gómez, Ángel; Tojal Sierra, Lucas; Fortuny Fraub, Elena; Goicolea Güemeza, Leire; Aboitiz Uribarria, Ane; Portillo, María Puy; Toledo, Estefania; Schröder, Helmut, 1958-; Salas Salvadó, Jordi; Arós, Fernando (Elsevier, 2018)
    BACKGROUND: Left ventricle diastolic dysfunction (LVDD) is a common finding in high risk individuals, its presence being associated with reduced exercise capacity (EC). We assessed the prevalence of LVDD, applying the 2016 ...
  • Does the Mediterranean diet counteract the adverse effects of abdominal adiposity?
    Eguaras, Sonia; Toledo, Estefania; Buil-Cosiales, Pilar; Salas-Salvadó, Jordi; Corella, Dolores; Gutierrez-Bedmar, Mario; Santos-Lozano, José; Arós, Fernando; Fiol, Miquel; Fitó Colomer, Montserrat; Ros, Emilio; Serra-Majem, Luis; Pinto, Xavier; Martínez, José Alfredo; Sorlí, José Vicente; Muñoz, Miguel Ángel; Basora, Josep; Estruch, Ramón; Martínez-González, Miguel A.; PREDIMED investigators (Elsevier, 2015)
    BACKGROUND AND AIM: We tested the hypothesis that an intervention with a Mediterranean diet (MeDiet) could mitigate the well-known harmful effects of abdominal obesity on cardiovascular health. METHODS AND RESULTS: We ...
  • Egg consumption and cardiovascular disease according to diabetic status: The PREDIMED study
    Díez-Espino, J.; Basterra-Gortari, F. Javier; Salas-Salvadó, Jordi; Buil-Cosiales, Pilar; Corella, Dolores; Schröder, Helmut, 1958-; Estruch, Ramón; Ros, Emilio; Gómez-Gracia, Enrique; Arós, Fernando; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Pintó Sala, Xavier; Babio, Nancy; Quiles, Laura; Fitó Colomer, Montserrat; Martí, Amelia; Toledo, Estefania; PREDIMED investigators (Elsevier, 2017)
    BACKGROUND: Eggs are a major source of dietary cholesterol and their consumption has been sometimes discouraged. A relationship between egg consumption and the incidence of cardiovascular disease (CVD) has been suggested ...
  • Energy balance and risk of mortality in spanish older adults
    Lassale, Camille; Hernáez, Álvaro; Toledo, Estefania; Castañer, Olga; Sorlí, José Vicente; Salas Salvadó, Jordi; Estruch, Ramón; Ros, Emilio; Alonso-Gómez, Ángel; Lapetra, José; Cueto, Raquel; Fiol, Miquel; Serra Majem, Lluís; Pinto, Xavier; Gea, Alfredo; Corella, Dolores; Babio, Nancy; Fitó Colomer, Montserrat; Schröder, Helmut, 1958- (MDPI, 2021)
    Clinical data on the direct health effects of energy deficit or surplus beyond its impact on body weight are scarce. We aimed to assess the association with all-cause, cardiovascular and cancer mortality of (1) sustained ...
  • Influence of lifestyle factors and staple foods from the Mediterranean diet on non-alcoholic fatty liver disease among older individuals with metabolic syndrome features
    Bullón Vela, María Vanessa; Abete, Itziar; Tur, J. Antoni; Pintó Sala, Xavier; Corbella, Emili; Martínez-González, Miguel A.; Toledo, Estefania; Corella, Dolores; Macías-González, Manuel; Tinahones Madueño, Francisco José; Fitó Colomer, Montserrat; Estruch, Ramón; Ros, Emilio; Salas Salvadó, Jordi; Daimiel, Lidia; Zulet, M. Angeles; Martínez, José Alfredo; PREDIMED-PLUS investigators (Elsevier, 2021)
    Objective: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver morbidity. This condition often is accompanied by obesity, diabetes, and metabolic syndrome (MetS). The aim of this study was ...
  • Longitudinal association of changes in diet with changes in body weight and waist circumference in subjects at high cardiovascular risk: the PREDIMED trial
    Konieczna, Jadwiga; Romaguera Bosch, Dora; Pereira, Verónica; Fiol, Miquel; Razquin, Cristina; Estruch, Ramón; Asensio, Eva María; Babio, Nancy; Fitó Colomer, Montserrat; Gómez Gracia, Enrique; Ros, Emilio; Lapetra, José; Arós, Fernando; Serra Majem, Lluís; Pintó Sala, Xavier; Toledo, Estefania; Sorlí, José Vicente; Bulló, Mònica; Schröder, Helmut, 1958-; Martínez-González, Miguel A. (BioMed Central, 2019)
    Background: Consumption of certain foods is associated with long-term weight gains and abdominal fat accumulation in healthy, middle-aged and young, non-obese participants. Whether the same foods might be associated with ...
  • Mediterranean diet and invasive breast Cancer risk among women at high cardiovascular risk in the PREDIMED trial: a randomized clinical trial
    Toledo, Estefania; Fitó Colomer, Montserrat; Martínez-González, Miguel A. (American Medical Association, 2015)
    IMPORTANCE: Breast cancer is the leading cause of female cancer burden, and its incidence has increased by more than 20% worldwide since 2008. Some observational studies have suggested that the Mediterranean diet may reduce ...
  • Mediterranean diet and physical activity decrease the initiation of cardiovascular drug use in high cardiovascular risk individuals: a cohort study
    Ribó Coll, Margarita; Castro-Barquero, Sara; Lassale, Camille; Sacanella, Emilio; Ros, Emilio; Toledo, Estefania; Sorlí, José Vicente; Díaz López, Andrés; Lapetra, José; Muñoz-Bravo, Carlos; Arós, Fernando; Fiol, Miquel; Serra Majem, Lluís; Pinto, Xavier; Castañer, Olga; Fernández Lázaro, César I.; Portolés, Olga; Babio, Nancy; Estruch, Ramón; Hernáez, Álvaro (MDPI, 2021)
    Our aim was to assess whether long-term adherence to a Mediterranean diet (MedDiet) and leisure-time physical activity (LTPA) were associated with a lower initiation of cardiovascular drug use. We studied the association ...
  • Metabolites of glutamate metabolism are associated with incident cardiovascular events in the PREDIMED PREvención con DIeta MEDiterránea (PREDIMED) Trial.
    Zheng, Yan; Hu, Frank B.; Ruiz-Canela, Miguel; Clish, Clary B.; Dennis, Courtney; Salas-Salvadó, Jordi; Hruby, Adela; Liang, Liming; Toledo, Estefania; Corella, Dolores; Ros, Emilio; Fitó Colomer, Montserrat; Gómez-Gracia, Enrique; Arós, Fernando; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Estruch, Ramón; Martínez-González, Miguel A. (Willey, 2016)
    BACKGROUND: Glutamate metabolism may play a role in the pathophysiology of cardiometabolic disorders. However, there is limited evidence of an association between glutamate-related metabolites and, moreover, changes in ...
  • Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study
    Yu, Edward; Ruiz-Canela, Miguel; Hu, Frank B.; Clish, Clary B.; Corella, Dolores; Salas-Salvadó, Jordi; Hruby, Adela; Fitó Colomer, Montserrat; Liang, Liming; Toledo, Estefania; Ros, Emilio; Estruch, Ramón; Gómez-Gracia, Enrique; Lapetra, José; Arós, Fernando; Romaguera Bosch, Dora; Serra-Majem, Luis; Guasch Ferré, Marta; Wang, Dong D.; Martínez-González, Miguel A. (Oxford University Press, 2017)
    CONTEXT: Arginine, its methylated metabolites, and other metabolites related to the urea cycle have been independently associated with cardiovascular risk, but the potential causal meaning of these associations (positive ...
  • Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study
    Guasch Ferré, Marta; Hu, Frank B.; Ruiz-Canela, Miguel; Bulló, Mònica; Toledo, Estefania; Wang, Dong D.; Corella, Dolores; Gómez Gracia, Enrique; Fiol, Miquel; Estruch, Ramón; Lapetra, José; Fitó Colomer, Montserrat; Arós, Fernando; Serra-Majem, Luis; Ros, Emilio; Dennis, Courtney; Liang, Liming; Clish, Clary B.; Martínez-González, Miguel A.; Salas-Salvadó, Jordi (Wiley, 2017)
    BACKGROUND: The relationship between plasma concentrations of betaine and choline metabolism and major cardiovascular disease (CVD) end points remains unclear. We have evaluated the association between metabolites from the ...
  • Replacing red meat and processed red meat for white meat, fish, legumes or eggs is associated with lower risk of incidence of metabolic syndrome.
    Becerra-Tomás, Nerea; Babio, Nancy; Martínez-González, Miguel A.; Corella, Dolores; Estruch, Ramón; Emilio, Ros; Fitó Colomer, Montserrat; Serra-Majem, Luis; Salaverria, Itziar; Lamuela-Raventós, Rosa M.; Lapetra, José; Gómez-Gracia, Enrique; Fiol, Miquel; Toledo, Estefania; Sorlí, José Vicente; Pedret-Llaberia, Maria Roser; Salas-Salvadó, Jordi (Elsevier, 2016)
    BACKGROUND & AIMS: Few studies have assessed the association between consumption of red meat (RM) and processed red meats (PRM) and the incidence of metabolic syndrome (MetS) and results have been inconsistent. We investigated ...
  • The Effect of a Mediterranean Diet on the Incidence of Cataract Surgery
    García-Layana, Alfredo; Gianfranco, Ciufo; Toledo, Estefania; Martínez-González, Miguel A.; Corella, Dolores; Fitó Colomer, Montserrat; Estruch, Ramón; Gómez-Gracia, Enrique; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Pinto, Xavier; Portillo, María P.; Sorlí, José Vicente; Bulló, Mònica; Vinyoles, Ernest; Sala Vila, Aleix; Ros, Emilio; Salas-Salvadó, Jordi; Arós, Fernando (MDPI, 2017)
    BACKGROUND: Cataract is a leading cause of vision impairment worldwide, and surgery is the only available treatment. The process that initiates lens opacification is dependent on the oxidative stress experienced by the ...
  • Virgin olive oil and health: summary of the III International conference on virgin olive oil and health consensus report, JAEN (Spain) 2018
    Gaforio, José J.; Visioli, Francesco; Alarcón-de-la-Lastra, Catalina; Castañer, Olga; Delgado-Rodríguez, Miguel; Fitó Colomer, Montserrat; Hernández, Antonio F.; Huertas, Jesús R.; Martínez-González, Miguel A.; Menendez, Javier A.; de la Osada, Jesús; Papadaki, Angeliki; Parrón, Tesifón; Pereira, Jorge E.; Rosillo, María A.; Sánchez-Quesada, Cristina; Schwingshackl, Lukas; Toledo, Estefania; Tsatsakis, Aristidis M. (MDPI, 2019)
    The Mediterranean diet is considered as the foremost dietary regimen and its adoption is associated with the prevention of degenerative diseases and an extended longevity. The preeminent features of the Mediterranean diet ...