Browsing by Author "Subirana Cachinero, Isaac"

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  • Rodrigo, Emilio; Pich, Sara; Subirana Cachinero, Isaac; Fernandez-Fresnedo, Gema; Barreda Monteoliva, Paloma; Ferrer-Costa, Carles; de Francisco, Angel Luis M.; Salas, Eduardo; Elosua Llanos, Roberto; Arias, Manuel (Oxford University Press, 2017)
    BACKGROUND: Coronary heart disease (CHD) is the primary cause of death in individuals with chronic kidney disease (CKD), but current equations for assessing coronary risk have low accuracy in this group. We have reported ...
  • Dégano, Irene R.; Subirana Cachinero, Isaac; Torre, Marina; Grau Magaña, Maria; Vila, Joan; Fusco, Danilo; Kirchberger, Inge; Ferrières, Jean; Malmivaara, Antti; Azevedo, Ana; Meisinger, Christa; Bongard, Vanina; Farmakis, Dimitrios; Davoli, Marina; Häkkinen, Unto; Araújo, Carla; Lekakis, John; Elosua Llanos, Roberto; Marrugat de la Iglesia, Jaume (Elsevier, 2015)
    BACKGROUND: Hospital performance models in acute myocardial infarction (AMI) are useful to assess patient management. While models are available for individual countries, mainly US, cross-European performance models are ...
  • Farràs Mañé, Marta; Arranz, Sara; Carrión, Sílvia; Subirana Cachinero, Isaac; Muñoz-Aguayo, D.; Blanchart, Gemma; Kool, Marjon; Solà, Rosa; Motilva, Maria-José; Escolà-Gil, Joan Carles; Rubió, Laura; Fernández-Castillejo, Sara; Pedret, Anna; Estruch, Ramón; Covas Planells, Maria Isabel; Fitó Colomer, Montserrat; Hernáez, Álvaro; Castañer, Olga (MDPI, 2019)
    The consumption of antioxidant-rich foods such as virgin olive oil (VOO) promotes high-density lipoprotein (HDL) anti-atherogenic capacities. Intake of functional VOOs (enriched with olive/thyme phenolic compounds (PCs)) ...
  • Musameh, Muntaser D.; Wang, William Y. S.; Nelson, Christopher P.; Lluís Ganella, Carla, 1984-; Debiec, Radoslaw; Subirana Cachinero, Isaac; Elosua Llanos, Roberto; Balmforth, Anthony J.; Ball, Stephen G.; Hall, Alistair S.; Kathiresan, Sekar; Thompson, John R.; Lucas, Gavin, 1977-; Samani, Nilesh J.; Tomaszewski, Maciej (Public Library of Science, 2015)
    OBJECTIVE: Only a small fraction of coronary artery disease (CAD) heritability has been explained by common variants identified to date. Interactions between genes of importance to cardiovascular regulation may account for ...
  • Gimeno Vázquez, Eva; Subirana Cachinero, Isaac; Gómez Pérez, Miguel Angel; Díaz, Javier; Sanchez Gonzalez, Blanca; García-Pallarols, Francesc; Martínez, Laia; Ble, Mireia; Molina Ferragut, Luis; Belarte Tornero, Laia Carla; Abella Monreal, Eugenia; Elosua Llanos, Roberto; Comín Colet, Josep; Salar Silvestre, Antonio (Wiley, 2019)
    OBJECTIVE: To evaluate the role of N-terminal pro-brain-type natriuretic peptide (NT-proBNP) and a cardiovascular (CV) risk score named FRESCO for predicting anthracycline-induced cardiotoxicity (AIC) in diffuse large ...
  • Fernández Sanlés, Alba, 1988-; Sayols, Sergi; Subirana Cachinero, Isaac; Dégano, Irene R.; Elosua Llanos, Roberto (Elsevier, 2017)
    BACKGROUND AND AIMS: The aim of this study was to perform a systematic review of the association between DNA methylation and coronary heart disease (CHD) or related atherosclerotic traits. METHODS: A systematic review was ...
  • Sayols, Sergi; Fernández Sanlés, Alba, 1988-; Prats Uribe, Albert; Subirana Cachinero, Isaac; Plusquin, Michelle; Künzli, Nino; Marrugat de la Iglesia, Jaume; Basagaña Flores, Xavier; Elosua Llanos, Roberto (Elsevier, 2019)
    INTRODUCTION: Limited evidence suggests that epigenetic mechanisms may partially mediate the adverse effects of air pollution on health. Our aims were to identify new genomic loci showing differential DNA methylation ...
  • Oristrell, Joaquim; Oliva, Joan Carles; Subirana Cachinero, Isaac; Casado, Enrique; Domínguez, Didier; Toloba, Andrea; Aguilera, Patricia; Esplugues, Joan; Fafián, Pilar; Grau Magaña, Maria (MDPI, 2021)
    Treatment with calcitriol, the hormonal form of vitamin D, has shown beneficial effects in experimental models of acute lung injury. In this study, we aimed to analyze the associations between calcitriol supplementation ...
  • Dégano, Irene R.; Camps-Vilaró, Anna; Subirana Cachinero, Isaac; García-Mateo, Nadia; Cidad, Pilar; Muñoz Aguayo, Daniel; Puigdecanet Riubugent, Eulàlia; Nonell Mazelón, Lara; Vila, Joan; Crepaldi, Felipe M.; Gonzalo-Calvo, David de; Llorente-Cortés, Vicenta; Pérez García, María Teresa; Elosua Llanos, Roberto; Fitó Colomer, Montserrat; Marrugat de la Iglesia, Jaume (MDPI, 2020)
    Risk prediction tools cannot identify most individuals at high coronary artery disease (CAD) risk. Oxidized low-density lipoproteins (oxLDLs) and microRNAs are actively involved in atherosclerosis. Our aim was to examine ...
  • Schröder, Helmut, 1958-; Serra-Majem, Luis; Subirana Cachinero, Isaac; Izquierdo Pulido, Maria; Fitó Colomer, Montserrat; Elosua Llanos, Roberto (Cambridge University Press, 2016)
    Higher monetary diet cost is associated with healthier food choices and better weight management. How changes in diet cost affect changes in diet quality and weight remains unknown. The aim of this study was to assess the ...
  • Maragaño Lizama, Patricio; Ríos, Diana L.; Subirana Cachinero, Isaac; Toloba, Andrea; Camps-Vilaró, Anna; Belzares, Oward; Pacheco, Claudio; Cerro, Cristina; Wehinger, Sergio; Fuentes, Eduardo; Marrugat de la Iglesia, Jaume; Palomo, Iván (MDPI, 2021)
    The present study aimed to determine the relationship between the prevalence of cardiovascular risk factors and the number and severity of coronary artery atherosclerotic lesions obtained by coronary angiography. We reviewed ...
  • Fernández-Bergés, Daniel; Dégano, Irene R.; Subirana Cachinero, Isaac; Martí-Almor, Julio; Vila, Joan; Pérez-Fernández, Silvia; Martí-Almor, Julio; Elosua Llanos, Roberto; Marrugat de la Iglesia, Jaume; ATHOS investigators (BMJ Publishing Group, 2020)
    Objective: Primary percutaneous coronary intervention (P-PCI) has demonstrated its efficacy in patients with ST segment elevation myocardial infarction (STEMI). However, patients with STEMI ≥75 years receive less P-PCI ...
  • Almanza-Aguilera, Enrique; Hernáez, Álvaro; Corella, Dolores; Sanllorente Melenchón, Albert; Ros, Emilio; Portolés, Olga; Valussi, Julieta; Estruch, Ramón; Coltell, Oscar; Subirana Cachinero, Isaac; Canudas i Puig, Sílvia; Razquin, Cristina; Blanchart, Gemma; Nonell Mazelón, Lara; Fitó Colomer, Montserrat; Castañer, Olga (MDPI, 2020)
    We aimed to explore the differences in the whole transcriptome of peripheral blood mononuclear cells between elderly individuals with and without type 2 diabetes (T2D). We conducted a microarray-based transcriptome analysis ...
  • Elosua Llanos, Roberto; Lluís Ganella, Carla, 1984-; Subirana Cachinero, Isaac; Havulinna, Aki; Läll, Kristi; Lucas, Gavin, 1977-; Sayols, Sergi; Pietilä, Arto; Alver, Maris; Cabrera de León, Antonio; Sentí Clapés, Mariano; Siscovick, David; Mellander, Olle; Fischer, Krista; Salomaa, Veikko; Marrugat de la Iglesia, Jaume (Lippincott Williams & Wilkins, 2016)
    BACKGROUND: Cardiovascular risk factors tend to aggregate. The biological and predictive value of this aggregation is questioned and genetics could shed light on this debate. Our aims were to reappraise the impact of risk ...
  • Saumoy, Maria; Di Yacovo, Silvana; Pérez, S.; Sánchez Quesada, José Luis; Valdivielso, Jose Manuel; Subirana Cachinero, Isaac; Imaz, Arkaitz; Tiraboschi, Juan M.; García, Benito; Ordóñez Llanos, Jordi; Benítez, Susana; Podzamczer, Daniel; Grau Magaña, Maria (Wiley, 2021)
    Objectives: To compare the prevalence of carotid atherosclerosis in virologically suppressed HIV patients with that of a community sample, and to evaluate the capacity of various cardiovascular risk (CVR) equations for ...
  • Subirana Cachinero, Isaac; Camps-Vilaró, Anna; Elosua Llanos, Roberto; Marrugat de la Iglesia, Jaume; Tizón-Marcos, Helena; Palomo, Iván; Dégano, Irene R. (Dove Medical Press, 2022)
    Background and aims: cardiovascular (CV) risk functions are the recommended tool to identify high-risk individuals. However, their discrimination ability is not optimal. While the effect of biomarkers in CV risk prediction ...
  • Palou Márquez, Guillermo; Subirana Cachinero, Isaac; Nonell Mazelón, Lara; Fernández Sanlés, Alba, 1988-; Elosua Llanos, Roberto (BioMed Central, 2021)
    Background: The integration of different layers of omics information is an opportunity to tackle the complexity of cardiovascular diseases (CVD) and to identify new predictive biomarkers and potential therapeutic targets. ...
  • Fernández Sanlés, Alba, 1988-; Sayols Baixeras, Sergi, 1988-; Subirana Cachinero, Isaac; Sentí Clapés, Mariano; Pérez-Fernández, Silvia; Castro de Moura, Manuel; Esteller, Manel; Marrugat de la Iglesia, Jaume; Elosua Llanos, Roberto (BioMed Central, 2021)
    Background: The epigenetic landscape underlying cardiovascular disease (CVD) is not completely understood and the clinical value of the identified biomarkers is still limited. We aimed to identify differentially methylated ...
  • Martín-Peláez, Sandra; Mosele, Juana; Pizarro Lozano, Mª Nieves; Farràs Mañé, Marta; Torre Fornell, Rafael de la; Subirana Cachinero, Isaac; Pérez-Cano, Francisco José; Castañer, Olga; Solà, Rosa; Fernandez-Castillejo, Sara; Heredia, Saray; Farré Albaladejo, Magí; Motilva, Maria-José; Fitó Colomer, Montserrat (Springer, 2017)
    PURPOSE: To investigate the effect of virgin olive oil phenolic compounds (PC) alone or in combination with thyme PC on blood lipid profile from hypercholesterolemic humans, and whether the changes generated are related ...
  • Codina, Pau; Subirana Cachinero, Isaac; Bayes-Genis, Antoni (Wiley, 2021)
    Aims: Several heart failure (HF) web-based risk scores are currently used in clinical practice. Currently, we lack head-to-head comparison of the accuracy of risk scores. This study aimed to assess correlation and mortality ...