Browsing by Author "Shahraki, Aida"

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  • G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits
    Kossatz de Mello, Elk, 1977-; Diez Alarcia, Rebeca; Gaitonde, Supriya A.; Ramon Duaso, Carla, 1987-; Stepniewski, Tomasz Maciej, 1988-; Aranda García, David; Muneta Arrate, Itziar; Tepaz, Elodie; Saen-Oon, Suwipa; Soliva, Robert; Shahraki, Aida; Moreira, David; Brea, José; Loza, María I.; Torre Fornell, Rafael de la; Kolb, Peter; Bouvier, Michel; Meana, J. Javier; Robledo, Patricia, 1958-; Selent, Jana (Nature Research, 2024)
    G protein-coupled receptors (GPCRs) are sophisticated signaling machines able to simultaneously elicit multiple intracellular signaling pathways upon activation. Complete (in)activation of all pathways can be counterproductive ...
  • On the construction of LIECE models for the serotonin receptor 5-HT[Formula: see text]R
    Shahraki, Aida; Selent, Jana; Kolb, Peter (Springer, 2023)
    Computer-aided approaches to ligand design need to balance accuracy with speed. This is particularly true for one of the key parameters to be optimized during ligand development, the free energy of binding ([Formula: see ...

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