Browsing by Author "Serrano Figueras, Sergi"

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  • A 12-gene expression signature is associated with aggressive histological in prostate cancer: SEC14L1 and TCEB1 genes are potential markers of progression. American journal of pathology
    Agell, Laia; Hernández, Silvia; Nonell Mazelón, Lara; Lorenzo Perez, Marta; Puigdecanet Riubugent, Eulàlia; Muga, Silvia de; Juanpere, Nuria; Bermudo, Raquel; Fernández, Pedro Luís; Lorente Garin, José Antonio; Serrano Figueras, Sergi; Lloreta Trull, Josep, 1958- (Elsevier, 2012)
    The main challenge for clinical management of prostate cancer is to distinguish tumors that will progress faster and will show a higher tendency to recur from the more indolent ones. We have compared expression profiles ...
  • Anti-tumor activity of the combination of bendamustine with vorinostat in diffuse large B-cell lymphoma cells.
    Fernández Rodríguez, M. Concepción; Salar Silvestre, Antonio; Navarro, Alfons; Gimeno Vázquez, Eva; Pairet García, Silvia; Camacho Díaz, Laura; Ferraro Rosset, Mariana Paola; Serrano Figueras, Sergi; Besses Raebel, Carles; Bellosillo Paricio, Beatriz; Sanchez Gonzalez, Blanca (Taylor & Francis, 2016)
    Current standard-of-care therapy for diffuse large B-cell lymphoma (DLBCL) results in up to 40% of patients who either relapse or develop refractory disease. In this setting, further therapeutic improvements are needed. ...
  • FISH and immunohistochemical status of the hepatocyte growth factor receptor (c-Met) in 184 invasive breast tumors.
    Carracedo, Alma; Egervari, Kristof; Salido, Marta; Rojo, Federico; Arumí, Montserrat; Corominas Torres, Josep Maria; Corzo, Cristina; Tusquets Trias de Bes, Ignacio; Espinet Solà, Blanca; Rovira Guerín, Ana; Albanell Mestres, Joan; Szollosi, Zoltan; Serrano Figueras, Sergi; Solé Ristol, Francesc (BioMed Central, 2009)
  • Human papillomavirus and breast cancer: no evidence of association in a Spanish set of cases.
    Vernet-Tomás, Maria; Mena, Marisa; Alemany, Laia; Bravo, Ignacio G.; Sanjosé Llongueras, Silvia de; Nicolau, Pau; Bergueiro Flor, Alba; Corominas Torres, Josep Maria; Serrano Figueras, Sergi; Carreras Collado, Ramón; Lloveras Rubio, Belen (International Institute of Anticancer Research , 2015)
    BACKGROUND/AIM: Great controversy exists about the association between Human Papillomavirus (HPV) and breast tumors. The aim of this study was to explore the presence of HPV DNA in a large set of breast cancer cases. ...
  • Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals
    Magri, Giuliana, 1978-; Pybus Oliveras, Marc, 1985-; Sintes, Jordi; Lligé, David; Segura-Garzón, Daniel; Bascones Gleave, Sabrina, 1985-; Yeste, Ada; Grasset, Emilie K.; Gutzeit, Cindy; Uzzan, Mathieu; Ramanujam, Meera; van Zelm, Menno C.; Albero-González, Raquel; Vazquez de las Heras, Ivonne; Iglesias, Mar; Serrano Figueras, Sergi; Márquez, Lucía; Mercade, Elena; Mehandru, Saurabh; Cerutti, Andrea, 1965- (Elsevier, 2017)
    Secretory immunoglobulin A (SIgA) enhances host-microbiota symbiosis, whereas SIgM remains poorly understood. We found that gut IgM+ plasma cells (PCs) were more abundant in humans than mice and clonally related to a large ...
  • MET expression and copy number heterogeneity in nonsquamous non-small cell lung cancer (nsNSCLC).
    Casadevall Aguilar, David; Gimeno Beltran, Javier; Clavé Safont, Sergi; Taus García, Álvaro; Pijuan Andujar, Lara; Arumí de Dios, Miriam; Lorenzo Perez, Marta; Menendez Romero, Silvia; Cañadas Castillo, Israel, 1984-; Albanell Mestres, Joan; Serrano Figueras, Sergi; Espinet Solà, Blanca; Salido Galeote, Marta; Arriola Aperribay, Edurne (Impact Journals, 2015)
    OBJECTIVE: We aimed to assess MET intratumoral heterogeneity and its potential impact on biomarker-based patient selection as well as potential surrogate biomarkers of MET activation. METHODS: Our study included 120 patients ...
  • mTOR intersects antibody-inducing signals from TACI in marginal zone B cells
    Sintes, Jordi; Serrano Figueras, Sergi; Lloreta Trull, Josep, 1958-; Cerutti, Andrea, 1965- (Nature Publishing Group, 2017)
    Mechanistic target of rapamycin (mTOR) enhances immunity in addition to orchestrating metabolism. Here we show that mTOR coordinates immunometabolic reconfiguration of marginal zone (MZ) B cells, a pre-activated lymphocyte ...
  • ROS1 copy number alterations are frequent in non-small cell lung cancer
    Clavé Safont, Sergi; Gimeno Beltran, Javier; Muñoz-Mármol, Ana M.; Vidal Barrull, Joana; Reguart, Noemí; Carcereny, Enric; Pijuan Andujar, Lara; Menendez Romero, Silvia; Taus García, Álvaro; Mate, José Luís; Serrano Figueras, Sergi; Albanell Mestres, Joan; Espinet Solà, Blanca; Arriola Aperribay, Edurne; Salido Galeote, Marta (Impact Journals, 2014)
    OBJECTIVES: We aimed to determine the prevalence and partners of ROS1 rearrangements, to explore the correlation between FISH and IHC assays, and to investigate clinical implications of ROS1 copy number alterations (CNAs). ...