Hardy-Werbin, Max; Quiroga, Vanesa; Cirauqui, Beatriz; Romeo, Margarita; Felip, Eudald; Teruel, Iris; García, Juan José; Erasun, Carlos; España, Sofia; Cucurull, Marc; Montprad, Elisabeth; Pardo, Juan Carlos; Carballo, Dania; Velarde, José María; Margeli, Mireia
(Nature Research, 2019)
T-DM1 is an antibody drug conjugate that combines trastuzumab with emtansine via a stable thioether linker. In two phase III clinical trials, EMILIA and TH3RESA, T-DM1 was shown to be effective in HER2-positive metastatic ...