Browsing by Author "Robinson, Oliver"

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  • A systematic comparison of statistical methods to detect interactions in exposome-health associations
    Barrera Gómez, Jose; Agier, Lydiane; Portengen, Lützen; Chadeau-Hyam, Marc; Giorgis-Allemand, Lise; Siroux, Valérie; Robinson, Oliver; Vlaanderen, Jelle; González, Juan Ramón; Nieuwenhuijsen, Mark J.; Vineis, Paolo; Vrijheid, Martine; Vermeulen, Roel; Slama, Rémy; Basagaña Flores, Xavier (BioMed Central, 2017)
    There is growing interest in examining the simultaneous effects of multiple exposures and, more generally, the effects of mixtures of exposures, as part of the exposome concept (being defined as the totality of human ...
  • Cord blood epigenome-wide meta-analysis in six European-based child cohorts identifies signatures linked to rapid weight growth
    Alfano, Rossella; Zugna, Daniela; Barros, Henrique; Bustamante Pineda, Mariona; Chatzi, Leda; Ghantous, Akram; Herceg, Zdenko; Keski-Rahkonen, Pekka; Kok, Theo M. de; Nawrot, Tim S.; Relton, Caroline L.; Robinson, Oliver; Roumeliotaki, Theano; Scalbert, Augustin; Vrijheid, Martine; Vineis, Paolo; Richiardi, Lorenzo; Plusquin, Michelle (BioMed Central, 2023)
    Rapid postnatal growth may result from exposure in utero or early life to adverse conditions and has been associated with diseases later in life and, in particular, with childhood obesity. DNA methylation, interfacing ...
  • Cord blood metabolic signatures predictive of childhood overweight and rapid growth
    Handakas, Evangelos; Keski-Rahkonen, Pekka; Chatzi, Leda; Alfano, Rossella; Roumeliotaki, Theano; Plusquin, Michelle; Maitre, Léa; Richiardi, Lorenzo; Brescianini, Sonia; Scalbert, Augustin; Robinot, Nivonirina; Nawrot, Tim S.; Sassi, Franco; Vrijheid, Martine; Vineis, Paolo; Robinson, Oliver (Nature Research, 2021)
    Introduction: Metabolomics may identify biological pathways predisposing children to the risk of overweight and obesity. In this study, we have investigated the cord blood metabolic signatures of rapid growth in infancy ...
  • Cord blood metabolites and rapid postnatal growth as multiple mediators in the prenatal propensity to childhood overweight
    Alfano, Rossella; Plusquin, Michelle; Robinson, Oliver; Brescianini, Sonia; Chatzi, Leda; Keski-Rahkonen, Pekka; Handakas, Evangelos; Maitre, Léa; Nawrot, Tim S.; Robinot, Nivonirina; Roumeliotaki, Theano; Sassi, Franco; Scalbert, Augustin; Vrijheid, Martine; Vineis, Paolo; Richiardi, Lorenzo; Zugna, Daniela (Nature Research, 2022)
    Background: The mechanisms underlying childhood overweight and obesity are poorly known. Here, we investigated the direct and indirect effects of different prenatal exposures on offspring rapid postnatal growth and overweight ...
  • Early life multiple exposures and child cognitive function: A multi-centric birth cohort study in six European countries
    Julvez, Jordi; López Vicente, Mònica, 1988-; Warembourg, Charline; Maitre, Léa; Philippat, Claire; Gützkow, Kristine B.; Guxens Junyent, Mònica; Evandt, Jorunn; Andrušaitytė, Sandra; Burgaleta Díaz, Miguel, 1981-; Casas Sanahuja, Maribel; Chatzi, Leda; de Castro, Montserrat; Donaire González, David; Gražulevičienė, Regina; Hernandez-Ferrer, Carles, 1987-; Heude, Barbara; McEachan, Rosie; Mon-Williams, Mark; Nieuwenhuijsen, Mark J.; Robinson, Oliver; Sakhi, Amrit Kaur; Sebastián Gallés, Núria; Slama, Rémy; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Thomsen, Cathrine; Urquiza, José M.; Vafeiadi, Marina, 1983-; Basagaña Flores, Xavier; Vrijheid, Martine (Elsevier, 2021)
    Epidemiological studies mostly focus on single environmental exposures. This study aims to systematically assess associations between a wide range of prenatal and childhood environmental exposures and cognition. The study ...
  • Early-life environmental exposures and childhood obesity: an exposome-wide approach
    Vrijheid, Martine; Fossati, Serena; Maitre, Léa; Márquez, Sandra; Casas Sanahuja, Maribel; de Castro, Montserrat; Donaire González, David; Robinson, Oliver; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Urquiza, José M.; Valentín, Antònia; Warembourg, Charline; Nieuwenhuijsen, Mark J.; Basagaña Flores, Xavier; Chatzi, Leda (National Institute of Environmental Health Sciences, 2020)
    Background: Chemical and nonchemical environmental exposures are increasingly suspected to influence the development of obesity, especially during early life, but studies mostly consider single exposure groups. Objectives: ...
  • Early-life exposome and lung function in children in Europe: an analysis of data from the longitudinal, population-based HELIX cohort
    Agier, Lydiane; Basagaña Flores, Xavier; Maitre, Léa; Casas Sanahuja, Maribel; de Castro, Montserrat; Donaire González, David; Nieuwenhuijsen, Mark J.; Robinson, Oliver; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Urquiza, José M.; Valentín, Antònia; Vrijheid, Martine; Siroux, Valérie (Elsevier, 2019)
    Background: Several single-exposure studies have documented possible effects of environmental factors on lung function, but none has relied on an exposome approach. We aimed to evaluate the association between a broad range ...
  • Environmental burden of childhood disease in Europe
    Rojas Rueda, David, 1979-; Vrijheid, Martine; Robinson, Oliver; Gunn Marit, Aasvang; Gražulevičienė, Regina; Slama, Rémy; Nieuwenhuijsen, Mark J. (MDPI, 2019)
    Background: Environmental factors determine children's health. Quantifying the health impacts related to environmental hazards for children is essential to prioritize interventions to improve health in Europe. Objective: ...
  • Exposure to endocrine-disrupting chemicals during pregnancy and weight at 7 years of age: a multi-pollutant approach.
    Agay-Shay, Keren; Martínez Muriano, David; Valvi, Damaskini, 1983-; García Esteban, Raquel; Basagaña Flores, Xavier; Robinson, Oliver; Casas Sanahuja, Maribel; Sunyer Deu, Jordi; Vrijheid, Martine (National Institute of Environmental Health Sciences, 2015)
    BACKGROUND: Prenatal exposure to endocrine-disrupting chemicals (EDCs) may induce weight gain and obesity in children, but the obesogenic effects of mixtures have not been studied. OBJECTIVE: We evaluated the associations ...
  • Human Early Life Exposome (HELIX) study: a European population-based exposome cohort
    Maitre, Léa; De Bont, Jeroen, 1989-; Casas Sanahuja, Maribel; Robinson, Oliver; Basagaña Flores, Xavier; Borràs, Eva; Bustamante Pineda, Mariona; de Castro, Montserrat; Donaire González, David; Estivill, Xavier, 1955-; Fossati, Serena; González, Juan Ramón; Hernández-Ferrer, Carles; Júlvez Calvo, Jordi; Manzano Salgado, Cyntia Beatriz, 1987-; Sabidó Aguadé, Eduard, 1981-; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Urquiza, José M.; van Gent, Diana; Vives Usano, Marta, 1990-; Warembourg, Charline; Nieuwenhuijsen, Mark J.; Vrijheid, Martine (BMJ Publishing Group, 2018)
    PURPOSE: Essential to exposome research is the collection of data on many environmental exposures from different domains in the same subjects. The aim of the Human Early Life Exposome (HELIX) study was to measure and ...
  • The Human Early-Life Exposome (HELIX): project rationale and design
    Vrijheid, Martine; Robinson, Oliver; Basagaña Flores, Xavier; Bustamante Pineda, Mariona; Casas Sanahuja, Maribel; Estivill, Xavier, 1955-; van Gent, Diana; González Ruiz, Juan Ramón; Júlvez Calvo, Jordi; Kogevinas, Manolis; Sabidó Aguadé, Eduard, 1981-; Sunyer Deu, Jordi; Nieuwenhuijsen, Mark J. (National Institute of Environmental Health Sciences (NIEHS), 2014)
    Background: Developmental periods in early life may be particularly vulnerable to impacts of environmental exposures. Human research on this topic has generally focused on single exposure–health effect relationships. The ...
  • Maternal consumption of seafood in pregnancy and child neuropsychological development: a longitudinal study based on a population with high consumption levels
    Júlvez Calvo, Jordi; Mendez, Michelle A.; Fernández-Barrés, Sílvia; Romaguera Bosch, Dora; Vioque, Jesus; Llop, Sabrina; Ibarluzea, Jesús; Guxens Junyent, Mònica; Avella García, Claudia B., 1982-; Tardón, Adonina; Riaño, Isolina; Andiarena, Ainara; Robinson, Oliver; Arija, Victoria; Esnaola, Mikel; Ballester Díez, Ferran; Sunyer Deu, Jordi (Oxford University Press, 2016)
    Seafood consumption during pregnancy is thought to be beneficial for child neuropsychological development, but to our knowledge no large cohort studies with high fatty fish consumption have analyzed the association by ...
  • Multiple environmental exposures in early-life and allergy-related outcomes in childhood
    Granum, Berit; Casas Sanahuja, Maribel; Warembourg, Charline; de Castro, Montserrat; Donaire González, David; Maitre, Léa; Robinson, Oliver; Tamayo-Uria, Ibon; Urquiza, José M.; Nieuwenhuijsen, Mark J.; Vrijheid, Martine (Elsevier, 2020)
    Introduction: Early onset and high prevalence of allergic diseases result in high individual and socio-economic burdens. Several studies provide evidence for possible effects of environmental factors on allergic diseases, ...
  • Prenatal and childhood traffic-related air pollution exposure and telomere length in european children: The HELIX Project
    Clemente Batalha Pardal, Diana, 1990-; Vrijheid, Martine; Martens, Dries S.; Bustamante Pineda, Mariona; Chatzi, Leda; Danileviciute, Asta; de Castro, Montserrat; Gražulevičienė, Regina; Gutzkow, Kristine B.; Lepeule, Johanna; Maitre, Léa; McEachan, Rosemary R.C.; Robinson, Oliver; Schwarze, Per E.; Tamayo-Uria, Ibon; Vafeiadi, Marina, 1983-; Wright, John; Slama, Rémy; Nieuwenhuijsen, Mark J.; Nawrot, Tim S. (National Institute of Environmental Health Sciences, 2019)
    Background: Telomere length is a molecular marker of biological aging. Objective: Here we investigated whether early-life exposure to residential air pollution was associated with leukocyte telomere length (LTL) at 8 y of ...
  • Prenatal exposure to persistent organic pollutants and childhood obesity: A systematic review and meta-analysis of human studies
    Stratakis, Nikos; Rock, Sarah; La Merrill, Michele A.; Saez, Marc; Robinson, Oliver; Fecht, Daniela; Vrijheid, Martine; Valvi, Damaskini, 1983-; Conti, David V.; McConnell, Rob; Chatzi, Vaia Lida (Wiley, 2022)
    We conducted a systematic review and meta-analysis of the associations between prenatal exposure to persistent organic pollutants (POPs) and childhood obesity. We focused on organochlorines (dichlorodiphenyltrichloroethane ...
  • The early-life exposome: Description and patterns in six European countries
    Tamayo-Uria, Ibon; Maitre, Léa; Nieuwenhuijsen, Mark J.; Casas Sanahuja, Maribel; de Castro, Montserrat; Robinson, Oliver; Urquiza, José M.; Warembourg, Charline; Vrijheid, Martine; Basagaña Flores, Xavier (Elsevier, 2019)
    Characterization of the "exposome", the set of all environmental factors that one is exposed to from conception onwards, has been advocated to better understand the role of environmental factors on chronic diseases. Here, ...
  • Urban environment during early-life and blood pressure in young children
    Warembourg, Charline; Nieuwenhuijsen, Mark J.; Ballester, Ferran; de Castro, Montserrat; Chatzi, Leda; Esplugues, Ana; Heude, Barbara; Maitre, Léa; McEachan, Rosemary R.C.; Robinson, Oliver; Slama, Rémy; Sunyer Deu, Jordi; Urquiza, José M.; Wright, John; Basagaña Flores, Xavier; Vrijheid, Martine (Elsevier, 2021)
    Background: The urban environment is characterised by many exposures that may influence hypertension development from early life onwards, but there is no systematic evaluation of their impact on child blood pressure (BP). ...
  • Urine metabolic signatures of multiple environmental pollutants in pregnant women: an exposome approach
    Maitre, Léa; Robinson, Oliver; Martínez, David; Toledano, Mireille B.; Ibarluzea, Jesús; Marina, Loreto Santa; Sunyer Deu, Jordi; Villanueva, Cristina M.; Keun, Hector C.; Vrijheid, Martine; Coen, Muireann (American Chemical Society (ACS), 2018)
    Exposure to environmental pollutants, particularly during pregnancy, can have adverse consequences on child development but little is known about the effects of pollutant mixtures on endogenous metabolism in pregnant women. ...
  • Variability of urinary concentrations of non-persistent chemicals in pregnant women and school-aged children
    Casas Sanahuja, Maribel; Basagaña Flores, Xavier; Manzano Salgado, Cyntia Beatriz, 1987-; De Bont, Jeroen, 1989-; Donaire González, David; Gonzalez, Juan Ramon; Gracia Lavedan, Esther; Pañella, Pau; Robinson, Oliver; Urquiza, José M.; Vrijheid, Martine (Elsevier, 2018)
    Background: Exposome studies are challenged by exposure misclassification for non-persistent chemicals, whose temporal variability contributes to bias in dose-response functions. Objectives: We evaluated the variability ...