Browsing by Author "Redondo Pachón, María Dolores"

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  • Activation of final complement components after kidney transplantation as a marker of delayed graft function severity
    Arias Cabrales, Carlos Enrique; Riera Oliva, Marta; Pérez-Sáez, María José; Gimeno Beltran, Javier; Benito, David; Redondo Pachón, María Dolores; Burballa Tàrrega, Carla, 1988-; Crespo Barrio, Marta; Pascual Santos, Julio; Rodríguez, Eva (Oxford University Press, 2020)
    Background: Ischaemia-reperfusion (I/R) damage is a relevant cause of delayed graft function (DGF). Complement activation is involved in experimental I/R injury, but few data are available from kidney transplant (KT) ...
  • Calcineurin and mTOR inhibitors have opposing effects on regulatory T cells while reducing regulatory B cell populations in kidney transplant recipients.
    Latorre, Irene; Esteve-Solé, Ana; Redondo Pachón, María Dolores; Giest, Sandra; Argilaguet Marqués, Jordi, 1977-; Álvarez, Sara; Peligero Cruz, Cristina, 1986-; Forstmann, Isabelle; Crespo Barrio, Marta; Pascual Santos, Julio; Meyerhans, Andreas (Elsevier, 2016)
    BACKGROUND: Regulatory B (Breg) and T (Treg) cells represent a biomarker for tolerance in transplant patients. Despite the importance of Treg and Breg in transplantation and the suggested crosstalk between both suppressive ...
  • Clinical profiles in renal patients with COVID-19
    Arenas Jiménez, María Dolores; Crespo Barrio, Marta; Pérez-Sáez, María José; Collado Nieto, Silvia; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Barbosa Puig, Francisco; Buxeda, Anna; Burballa Tàrrega, Carla, 1988-; Sans Atxer, Laia; Vázquez, Susana; Oliveras, Anna; Mir, Marisa; Outón González, Sara; Galceran Herrera, Isabel; Solà Porta, Eulàlia; Sierra Ochoa, Adriana; Barrios Barrera, Clara; Rodriguez García, Eva; Cao Baduell, Higinio (MDPI, 2020)
    The COVID-19 pandemic has led to frequent referrals to the emergency department on suspicion of this infection in maintenance hemodialysis (MHD) and kidney transplant (KT) patients. We aimed to describe their clinical ...
  • COVID-19 in elderly kidney transplant recipients
    Crespo Barrio, Marta; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Burballa Tàrrega, Carla, 1988-; Vázquez, Susana; Mir, Marisa; Sierra Ochoa, Adriana; Collado Nieto, Silvia; Barrios Barrera, Clara; Rodriguez García, Eva; Sans Atxer, Laia; Barbosa Puig, Francisco; Cao Baduell, Higinio; Arenas Jiménez, María Dolores; Güerri Fernández, Roberto; Horcajada Gallego, Juan Pablo; Pascual Santos, Julio (Wiley, 2020)
    The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 ...
  • COVID-19 in grade 4-5 chronic kidney disease patients
    Collado Nieto, Silvia; Arenas Jiménez, María Dolores; Barbosa Puig, Francisco; Cao Baduell, Higinio; Montero, Maria Milagro; Villar García, Judit; Barrios Barrera, Clara; Rodriguez García, Eva; Sans Atxer, Laia; Sierra Ochoa, Adriana; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Coca, Armando; Maiques LLacer, José María; Güerri Fernández, Roberto; Horcajada Gallego, Juan Pablo; Crespo Barrio, Marta; Pascual Santos, Julio (Karger (S. Karger AG), 2020)
    Introduction: Chronic kidney disease (CKD) increases the risk of mortality during coronavirus disease 2019 (COVID-19) episodes, and some reports have underlined the high incidence and severity of this infection in dialysis ...
  • Dual Role of Natural Killer Cells on Graft Rejection and Control of Cytomegalovirus Infection in Renal Transplantation
    López-Botet, Miguel; Vilches, Carlos; Redondo Pachón, María Dolores; Muntasell i Castellví, Aura, 1972-; Pupuleku, Aldi, 1985-; Yélamos López, José; Pascual Santos, Julio; Crespo Barrio, Marta (Frontiers, 2017)
    Allograft rejection constitutes a major complication of solid organ transplantation requiring prophylactic/therapeutic immunosuppression, which increases susceptibility of patients to infections and cancer. Beyond the ...
  • Early hypertransaminasemia after kidney transplantation: significance and evolution according to donor type
    Solà Porta, Eulàlia; Redondo Pachón, María Dolores; Arias Cabrales, Carlos Enrique; Navazo, Diego; Buxeda, Anna; Burballa Tàrrega, Carla, 1988-; Crespo Barrio, Marta; García-Retortillo, Montserrat; Pascual Santos, Julio; Pérez-Sáez, María José (MDPI, 2021)
    Early hypertransaminasemia after kidney transplantation (KT) is frequent. It has been associated with the crosstalk produced between the liver and the kidney in ischemia-reperfusion situations. However, the influence of ...
  • Frailty among chronic kidney disease patients on the kidney transplant waiting list: the sex-frailty paradox
    Pérez-Sáez, María José; Arias Cabrales, Carlos Enrique; Dávalos Yerovi, Vanesa; Redondo Pachón, María Dolores; Faura, Anna; Vera, María; Bach-Pascual, Anna; Pedreira Robles, Guillermo; Junyent-Iglesias, Ernestina; Crespo Barrio, Marta; Marco, Ester; Rodríguez-Mañas, Leocadio; Pascual Santos, Julio; FRAIL-MAR Study Group (Oxford University Press, 2021)
    Background: Frailty is defined as decreased physiologic reserve and resistance to stressors that predisposes patients towards poor health results. Its prevalence in chronic kidney disease (CKD) patients who are kidney ...
  • Gender differences in cancer risk after kidney transplantation
    Buxeda, Anna; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Bartolomé, Álvaro; Mir Fontana, M. Luisa; Pascual-Dapena, Ana; Sans, Anna; Duran Jordà, Xavier, 1974-; Crespo Barrio, Marta; Pascual Santos, Julio (Impact Journals, 2019)
    Kidney transplant (KT) recipients are at greater risk of developing some cancers than the general population. Moreover, cancer is the only cause of death that is currently increasing after kidney transplantation. We analyzed ...
  • Immunoguided discontinuation of prophylaxis for cytomegalovirus disease in kidney transplant recipients treated with antithymocyte globulin: A randomized clinical trial
    Páez-Vega, Aurora; Redondo Pachón, María Dolores; Crespo Barrio, Marta; Torre-Cisneros, Julian (Oxford University Press, 2022)
    Background: Antiviral prophylaxis is recommended in cytomegalovirus (CMV)-seropositive kidney transplant (KT) recipients receiving antithymocyte globulin (ATG) as induction. An alternative strategy of premature discontinuation ...
  • Impact of persistent and cleared preformed HLA DSA on kidney transplant outcomes
    Redondo Pachón, María Dolores; Pérez-Sáez, María José; Mir Fontana, M. Luisa; Gimeno Beltran, Javier; Llinàs-Mallol, Laura; García, Carmen; Hernández, Juan José; Yélamos López, José; Pascual Santos, Julio; Crespo Barrio, Marta (Elsevier, 2018)
    Preformed HLA donor-specific antibodies (DSA) only detected with Luminex have been associated with increased risk of antibody-mediated rejection (ABMR) and graft failure after kidney transplantation (KT). Their evolution ...
  • Impact of preformed and de novo anti-HLA DP antibodies in renal allograft survival.
    Redondo Pachón, María Dolores; Pascual Santos, Julio; Pérez-Sáez, María José; García, Carmen; Hernández, Juan José; Gimeno Beltran, Javier; Mir Fontana, M. Luisa; Crespo Barrio, Marta (Elsevier, 2016)
    The influence of antibodies against HLA-DP antigens detected with solid-phase assays on graft survival after kidney transplantation (KT) is uncertain. We evaluated with Luminex® the prevalence of pre- and posttransplant ...
  • Increased mortality after kidney transplantation in mildly frail recipients
    Pérez-Sáez, María José; Arias Cabrales, Carlos Enrique; Redondo Pachón, María Dolores; Burballa Tàrrega, Carla, 1988-; Buxeda, Anna; Bach-Pascual, Anna; Faura, Anna; Junyent, Ernestina; Marco, Ester; Rodríguez-Mañas, Leocadio; Crespo Barrio, Marta; Pascual Santos, Julio; FRAIL-MAR Study Group (Oxford University Press, 2022)
    Background: physical Frailty Phenotype (PFP) is the most used frailty instrument among kidney transplant recipients, classifying patients as pre-frail if they have 1-2 criteria and as frail if they have ≥3. However, different ...
  • Kidney transplantation outcomes from elderly donors after circulatory death: a comparison with elderly brain-dead donors
    Buxeda, Anna; Velis, Gonzalo; Arias Cabrales, Carlos Enrique; Zapatero, Ana; Burballa Tàrrega, Carla, 1988-; Redondo Pachón, María Dolores; Mir, Marisa; Crespo Barrio, Marta; Pascual Santos, Julio; Pérez-Sáez, María José (Oxford University Press, 2020)
    Background: The use of kidneys from elderly controlled donation after circulatory death (cDCD) donors has increased significantly in recent years. Concerns about outcomes achieved with these elderly cDCD kidneys have arisen. ...
  • Long-term evolution of the adaptive NKG2C + NK cell response to cytomegalovirus infection in kidney transplantation: an insight on the diversity of host-pathogen interaction
    Ataya Fernández, Michelle, 1993-; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Yélamos López, José; Alari-Pahissa, Elisenda; Pérez-Sáez, María José; Altadill, Mireia; Raïch-Regué, Dàlia; Vilches, Carlos; Pascual Santos, Julio; Crespo Barrio, Marta; López-Botet, Miguel (American Association of Immunologists - AAI, 2021)
    Human CMV infection is frequent in kidney transplant recipients (KTR). Pretransplant Ag-specific T cells and adaptive NKG2C+ NK cells associate with reduced incidence of infection in CMV+ KTR. Expansions of adaptive NKG2C+ ...
  • Long-term redistribution of peripheral lymphocyte subpopulations after switching from calcineurin to mTOR inhibitors in kidney transplant recipients
    Llinàs-Mallol, Laura; Redondo Pachón, María Dolores; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Yélamos López, José; Duran Jordà, Xavier, 1974-; Faura, Anna; López-Botet, Miguel; Pascual Santos, Julio; Crespo Barrio, Marta (MDPI, 2020)
    Classical immunosuppression based on steroids, calcineurin inhibitors, and mycophenolate results in several unwanted effects and unsatisfactory long-term outcomes in kidney transplantation (KT). New immunosuppressors search ...
  • Maintenance low dose systemic glucocorticoids have limited impact on bone strength and mineral density among incident renal allograft recipients: A pilot prospective cohort study
    Pérez-Saez, María José; Herrera, Sabina; Prieto-Alhambra, Daniel; Vilaplana, Laia; Nogués Solan, Francesc Xavier; Vera, María; Redondo Pachón, María Dolores; Mir Fontana, M. Luisa; Güerri Fernández, Roberto; Crespo Barrio, Marta; Díez Pérez, Adolfo; Pascual Santos, Julio (Elsevier, 2018)
    Soon after kidney transplant (KT), a decrease in parathormone and bone mineral density (BMD) occur, but little is known on the impact of KT on novel bone quality parameters including trabecular bone score (TBS) and bone ...
  • Mammalian target of rapamycin inhibitors combined with Calcineurin inhibitors as initial immunosuppression in renal transplantation: a meta-analysis
    Montero, Núria; Quero, Maria; Melilli, Edoardo; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Bestard, Oriol; Crespo Barrio, Marta; Cruzado, Josep Ma.; Pascual Santos, Julio (Lippincott Williams & Wilkins, 2019)
    Background: The current standard of care immunosuppressive regimen in kidney transplantation (KT) includes a combination of mycophenolates (MMF/MPA) with a calcineurin inhibitor (CNI). Methods: We designed a systematic ...
  • Manejo de la inmunosupresión en pacientes trasplantados de riñón con COVID19: estudio multicéntrico nacional derivado del registro COVID de la Sociedad Española de Nefrología
    López-Oliva, Maria O.; Redondo Pachón, María Dolores; Jimenez, Carlos (Elsevier, 2022)
    Introducción: la infección por SARS-CoV2 ha impactado de forma importante en los pacientes con trasplante renal causando una elevada mortalidad en los primeros meses de la pandemia. La reducción intencionada de la ...
  • MDRD o CKD-EPI en la estimación del filtrado glomerulardel donante renal vivo
    Burballa Tàrrega, Carla, 1988-; Crespo Barrio, Marta; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Mir Fontana, M. Luisa; Arias Cabrales, Carlos Enrique; Frances, Albert; Fumadó Ciutat, Lluis; Cecchini Rosell, Lluís; Pascual Santos, Julio (Elsevier, 2018)
    INTRODUCTION: The evaluation of the measured Glomerular Filtration Rate (mGFR) or estimated Glomerular Filtration Rate (eGFR) is key in the proper assessment of the renal function of potential kidney donors. We aim to study ...