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Browsing by Author "Puiggros Metje, Anna Maria"
Now showing items 1-15 of 15
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González Gascón y Marín, Isabel; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Hernández, José-Ángel; Grupo Español de Leucemia Linfática Crónica (GELLC); Grupo Cooperativo Español de Citogenética Hematológica (GCECGH) (Wiley, 2014)The prognosis of chronic lymphocytic leukemia (CLL) patients displaying trisomy 12 (+12) remains unclear. In this study, we analyzed the influence of the proportion of cells with +12, and other clinical and biologic factors, ...
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Hernández, José-Ángel; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Hernández-Rivas, Jesús María; Grupo Cooperativo Español de Citogenética Hematológica (GCECGH); Grupo Español de Leucemia Linfática Crónica (GELLC) (Public Library of Science, 2015)To analyze the impact of the 11q deleted (11q-) cells in CLL patients on the time to first therapy (TFT) and overall survival (OS), 2,493 patients with CLL were studied. 242 patients (9.7%) had 11q-. Fluorescence in situ ...
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Ramos Campoy, Silvia; Puiggros Metje, Anna Maria; Gimeno, Eva; Espinet Solà, Blanca (Ferrata Storti Foundation, 2022)Genome complexity has been associated with poor outcome in patients with chronic lymphocytic leukemia (CLL). Previous cooperative studies established five abnormalities as the cut-off that best predicts an adverse evolution ...
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Blanco Ares, Gonzalo, 1989-; Puiggros Metje, Anna Maria; Sherry, Barbara; Nonell Mazelón, Lara; Calvo Gonzalo, Xavier; Puigdecanet Riubugent, Eulàlia; Arnal, Magdalena; Rodríguez-Rivera, María; Gimeno Vázquez, Eva; Abella Monreal, Eugenia; Calon, Alexandre; Ferrer Del Alamo, Ana; Espinet Solà, Blanca (Elsevier, 2021)Several studies in chronic lymphocytic leukemia (CLL) patients have reported impaired immune cell functions, which contribute to tumor evasion and disease progression. However, studies on CLL-like monoclonal B-cell ...
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Prasad, Aparna; Rabionet, Raquel; Espinet Solà, Blanca; Zapata Ortiz, Luis, 1985-; Puiggros Metje, Anna Maria; Melero Vilella, Maria Carme; Puig, Anna; Sarria-Trujillo, Yaris; Ossowski, Stephan; Garcia-Muret, Maria P.; Estrach, Teresa; Servitje, Octavio; Lopez-Lerma, Ingrid; Gallardo Hernández, Fernando; Pujol Vallverdú, Ramon Maria; Estivill, Xavier, 1955- (Elsevier, 2016)Sézary syndrome is a leukemic form of cutaneous T-cell lymphoma with an aggressive clinical course. The genetic etiology of the disease is poorly understood, with chromosomal abnormalities and mutations in some genes being ...
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Blanco, Gonzalo; Puiggros Metje, Anna Maria; Rodríguez-Rivera, María; Gimeno Vázquez, Eva; Abella Monreal, Eugenia; Ferrer Del Alamo, Ana; Espinet Solà, Blanca (Impact Journals, 2016)Patients with chronic lymphocytic leukemia (CLL) harboring TP53 aberrations (TP53abs; chromosome 17p deletion and/or TP53 mutation) exhibit an unfavorable clinical outcome. Chromosome 8 abnormalities, namely losses of 8p ...
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Carrillo-Tornel, Salvador; Chen-Liang, Tzu Hua; Zurdo, María; Puiggros Metje, Anna Maria; Gómez-Llonín, Andrea; García-Malo, María Dolores; Cuenca-Zamora, Ernesto José; Ortuño, Francisco José; Hurtado López, Ana María; Espinet Solà, Blanca; Jerez, Andrés (Wiley, 2022)Studies prior to next-generation sequencing (NGS) showed that the frequent indolent course of chronic lymphocytic leukaemia (CLL) is related to most cells remaining quiescent in the G0 -G1 cell cycle phase, due to the ...
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Calvo Gonzalo, Xavier; García-Gisbert, Nieves; Parraga, Ivonne; Gibert, Joan; Florensa Brichs, Lourdes; Andrade-Campos, Marcio; Merchan, Brayan; García-Avila, Sara; Montesdeoca, Sara; Fernández-Rodríguez, C.; Salido Galeote, Marta; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Colomo Saperas, Luis Alberto; Roman-Bravo, David; Bellosillo Paricio, Beatriz; Ferrer Del Alamo, Ana; Arenillas Rocha, Leonor (American Society of Hematology, 2020)Oligomonocytic chronic myelomonocytic leukemia (OM-CMML) is defined as those myelodysplastic syndromes (MDSs) or myelodysplastic/myeloproliferative neoplasms, unclassifiable with relative monocytosis (≥10% monocytes) and ...
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Puiggros Metje, Anna Maria; Ramos Campoy, Silvia; Kamaso Navarro, Joanna; de la Rosa, Mireia; Salido Galeote, Marta; Melero Vilella, Maria Carme; Rodríguez-Rivera, María; Gimeno Vázquez, Eva; Calvo, Xavier; Arenillas Rocha, Leonor; Ferrer Del Alamo, Ana; Espinet Solà, Blanca (MDPI, 2022)Novel treatments in chronic lymphocytic leukemia (CLL) have generated interest regarding the clinical impact of genomic complexity, currently assessed by chromosome banding analysis (CBA) and chromosomal microarray analysis ...
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Calvo González, Xavier; Roman-Bravo, David; García Gisbert, Nieves, 1994-; Rodriguez-Sevilla, Juan José; García-Avila, Sara; Florensa Brichs, Lourdes; Gibert Fernandez, Joan 1988-; Fernández Rodríguez, M. Concepción; Salido Galeote, Marta; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Colomo Saperas, Luis Alberto; Bellosillo Paricio, Beatriz; Ferrer, Ana; Arenillas Rocha, Leonor (American Society of Hematology, 2022)atients with oligomonocytic chronic myelomonocytic leukemia (OM-CMML) are currently classified according to the 2017 World Health Organization myelodysplastic syndromes classification. However, recent data support considering ...
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Puiggros Metje, Anna Maria; Salido Galeote, Marta; Ferrer Del Alamo, Ana; Gimeno Vázquez, Eva; Abella Monreal, Eugenia; Espinet Solà, Blanca (Impact Journals, 2017)Genomic complexity identified by chromosome banding analysis (CBA) predicts a worse clinical outcome in CLL patients treated either with standard or new treatments. Herein, we analyzed the clinical impact of complex ...
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Puiggros Metje, Anna Maria; Blanco Ares, Gonzalo, 1989-; Muntasell i Castellví, Aura, 1972-; Rodríguez-Rivera, María; Nonell Mazelón, Lara; Altadill, Mireia; Puigdecanet Riubugent, Eulàlia; Arnal, Magdalena; Calvo, Xavier; Gimeno, Eva; Abella Monreal, Eugenia; Abrisqueta, Pau; Bosch José, Francesc Xavier, 1947-; Yélamos López, José; Ferrer, Ana; López-Botet, M. (Miguel); Espinet Solà, Blanca (Wiley, 2021)Introduction: Dysregulated NK cell-mediated immune responses contribute to tumor evasion in chronic lymphocytic leukemia (CLL), although the NK cell compartment in CLL-like monoclonal B-cell lymphocytosis (MBL) is poorly ...
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Blanco Ares, Gonzalo, 1989-; Vardi, Anna; Puiggros Metje, Anna Maria; Gómez-Llonín, Andrea; Muro, Manuel; Rodríguez-Rivera, María; Stalika, Evangelia; Abella Monreal, Eugenia; Gimeno Vázquez, Eva; López-Sánchez, Manuela; Senín Magan, Maria Alicia; Calvo, Xavier; Abrisqueta, Pau; Bosch José, Francesc Xavier, 1947-; Ferrer Del Alamo, Ana; Stamatopoulos, Kostas; Espinet Solà, Blanca (Taylor & Francis, 2018)Analysis of the T cell receptor (TR) repertoire of chronic lymphocytic leukemia-like monoclonal B cell lymphocytosis (CLL-like MBL) and early stage CLL is relevant for understanding the dynamic interaction of expanded B ...
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Ramos Campoy, Silvia; Puiggros Metje, Anna Maria; Kamaso, Joanna; Gimeno Vázquez, Eva; Salido, Marta; Calvo Gonzalo, Xavier; Espinet Solà, Blanca (MDPI, 2022)Chromothripsis (cth) has been associated with a dismal outcome and poor prognosis factors in patients with chronic lymphocytic leukemia (CLL). Despite being correlated with high genome instability, previous studies have ...
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García-Martín, Paloma; Espinet Solà, Blanca; Rodríguez-Sevilla, Juan José; Blanco Ares, Gonzalo, 1989-; Puiggros Metje, Anna Maria; Sainz, Juan (Nature Research, 2022)
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