Browsing by Author "Peter, Matthias"

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  • Biophysical properties of Saccharomyces cerevisiae and their relationship with HOG pathway activation
    Schaber, Jörg; Adrover Nadal, Miguel Angel; Eriksson, Emma; Pelet, Serge; Petelenz-Kurdziel, Elzbieta; Klein, Dagmara; Posas Garriga, Francesc; Goksör, Mattias; Peter, Matthias; Hohmann, Stefan; Klipp, E., 1965- (Springer Verlag, 2010)
    Parameterized models of biophysical and mechanical cell properties are important for predictive mathematical modeling of cellular processes. The concepts of turgor, cell wall elasticity, osmotically active volume, and ...
  • Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress
    Solé, Carme; Nadal Ribelles, Mariona, 1984-; Kraft, Claudine; Peter, Matthias; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (Nature Publishing Group, 2011)
    Protein ubiquitylation is a key process in the regulation of many cellular processes. The balance between the activity of ubiquitin ligases and that of proteases controls the level of ubiquitylation. In response to ...
  • Parallel feedback loops control the basal activity of the HOG MAPK signaling cascade
    Sharifian, Hoda; Lampert, Fabienne; Stojanovski, Klement; Regot Rodríguez de Mier, Sergi; Vaga, Stefania; Buser, Raymond; Lee, Sung Sik; Koeppl, Heinz; Posas Garriga, Francesc; Pelet, Serge; Peter, Matthias (Royal Society of Chemistry, 2015)
    Tight regulation of the MAP kinase Hog1 is crucial for survival under changing osmotic conditions. Interestingly, we found that Hog1 phosphorylates multiple upstream components, implying feedback regulation within the ...
  • Positive feedback induces switch between distributive and processive phosphorylation of Hog1
    Mosbacher, Maximilian; Lee, Sung Sik; Yaakov, Gilad; Nadal Ribelles, Mariona, 1984-; Nadal Clanchet, Eulàlia de; van Drogen, Frank; Posas Garriga, Francesc; Peter, Matthias; Claassen, Manfred (Nature Research, 2023)
    Cellular decision making often builds on ultrasensitive MAPK pathways. The phosphorylation mechanism of MAP kinase has so far been described as either distributive or processive, with distributive mechanisms generating ...