Browsing by Author "Pegueroles Queralt, Maria Cinta"

Sort by: Order: Results:

  • Biological processes modulating longevity across primates: a phylogenetic genome-phenome analysis
    Muntané, Gerard; Farré, Xavier; Rodríguez Pérez, Juan Antonio, 1985-; Pegueroles Queralt, Maria Cinta; Hughes, David; Magalhães, João Pedro de; Gabaldón Estevan, Juan Antonio, 1973-; Navarro i Cuartiellas, Arcadi, 1969- (Oxford University Press, 2018)
    Aging is a complex process affecting different species and individuals in different ways. Comparing genetic variation across species with their aging phenotypes will help understanding the molecular basis of aging and ...
  • HaploTypo: a variant-calling pipeline for phased genomes
    Pegueroles Queralt, Maria Cinta; Mixão, Verónica; Carreté Muñoz, Laia, 1990-; Molina, Manuel; Gabaldón Estevan, Juan Antonio, 1973- (Oxford University Press, 2020)
    SUMMARY: An increasing number of phased (i.e. with resolved haplotypes) reference genomes are available. However, the most genetic variant calling tools do not explicitly account for haplotype structure. Here, we present ...
  • Inversions and adaptation to the plant toxin ouabain shape DNA sequence variation within and between chromosomal inversions of Drosophila subobscura
    Pegueroles Queralt, Maria Cinta; Ferrés Coy, Albert; Martí Solano, Maria; Aquadro, Charles F.; Pascual, Marta; Mestres, Francesc (Nature Publishing Group, 2016)
    Adaptation is defined as an evolutionary process allowing organisms to succeed in certain habitats or conditions. Chromosomal inversions have the potential to be key in the adaptation processes, since they can contribute ...
  • Key Role of Amino Acid Repeat Expansions in the Functional Diversification of Duplicated Transcription Factors.
    Radó i Trilla, Núria, 1985-; Arató, Krisztina, 1981-; Pegueroles Queralt, Maria Cinta; Raya, Alicia; Luna, Susana de la; Albà Soler, Mar (Open University Press, 2015)
    The high regulatory complexity of vertebrates has been related to two rounds of whole genome duplication (2R-WGD) that occurred before the divergence of the major vertebrate groups. Following these events, many developmental ...
  • Long Non-Coding RNAs As Potential Novel Prognostic Biomarkers in Colorectal Cancer
    Saus Martínez, Ester; Brunet-Vega, Anna; Iraola Guzman, Susana; Pegueroles Queralt, Maria Cinta; Gabaldón Estevan, Juan Antonio, 1973-; Pericay, Carles (Frontiers, 2016)
    Colorectal cancer (CRC) is the fourth most common cause of death worldwide. Surgery is usually the first line of treatment for patients with CRC but many tumors with similar histopathological features show significantly ...
  • Patterns of genomic variation in the opportunistic pathogen candida glabrata suggest the existence of mating and a secondary association with humans
    Carreté Muñoz, Laia, 1990-; Ksiezopolska, Ewa; Pegueroles Queralt, Maria Cinta; Gómez-Molero, Emilia; Saus Martínez, Ester; Iraola Guzman, Susana; Loska, Damian; Bader, Olivier; Fairhead, Cécile; Gabaldón Estevan, Juan Antonio, 1973- (Elsevier, 2018)
    Candida glabrata is an opportunistic fungal pathogen that ranks as the second most common cause of systemic candidiasis. Despite its genus name, this yeast is more closely related to the model yeast Saccharomyces cerevisiae ...
  • Secondary structure impacts patterns of selection in human IncRNAs
    Pegueroles Queralt, Maria Cinta; Gabaldón Estevan, Juan Antonio, 1973- (BioMed Central, 2016)
    Background: Metazoans transcribe many long non-coding RNAs (lncRNAs) that are poorly conserved and whose function remains unknown. This has raised the questions of what fraction of the predicted lncRNAs is actually functional, ...
  • Selection following gene duplication shapes recent genome evolution in the pea aphid acyrthosiphon pisum
    Fernández, Rosa; Marcet Houben, Marina; Legeai, Fabrice; Richard, Gautier; Robin, Stéphanie; Wucher, Valentin; Pegueroles Queralt, Maria Cinta; Gabaldón Estevan, Juan Antonio, 1973-; Tagu, Denis (Oxford University Press (OUP), 2020)
    Ecology of insects is as wide as their diversity, which reflects their high capacity of adaptation in most of the environments of our planet. Aphids, with over 4,000 species, have developed a series of adaptations including ...
  • Transcriptomic analyses reveal groups of co-expressed, syntenic lncRNAs in four species of the genus Caenorhabditis
    Pegueroles Queralt, Maria Cinta; Iraola Guzman, Susana; Chorostecki, Uciel; Ksiezopolska, Ewa; Saus Martínez, Ester; Gabaldón Estevan, Juan Antonio, 1973- (Taylor & Francis, 2019)
    Long non-coding RNAs (lncRNAs) are a heterogeneous class of genes that do not code for proteins. Since lncRNAs (or a fraction thereof) are expected to be functional, many efforts have been dedicated to catalog lncRNAs in ...