Browsing by Author "Peña, Raúl"

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  • Curto, Josué; Valle Pérez, Beatriz del; Villarroel, Aida; Fuertes, Guillem; Vinyoles, Meritxell; Peña, Raúl; García de Herreros, Antonio; Duñach, Mireia (Wiley, 2018)
    Canonical and noncanonical Wnt pathways share some common elements but differ in the responses they evoke. Similar to Wnt ligands acting through the canonical pathway, Wnts that activate the noncanonical signaling, such ...
  • Herrera, Alberto; Herrera, Mercedes; Guerra-Perez, Natalia; Galindo-Pumariño, Cristina; Larriba, María Jesús; García-Barberán, Vanesa; Gil, Beatriz; Giménez-Moyano, Sara; Ferreiro-Monteagudo, Reyes; Veguillas, Pilar; Candia, Antonio; Peña, Raúl; Pinto, Jesús; García-Bermejo, Mª Laura; Muñoz, Alberto; García de Herreros, Antonio; Bonilla, Félix; Carrato, Alfredo; Peña, Cristina (Nature Research, 2018)
    Carcinomas, such as colon cancer, initiate their invasion by rescuing the innate plasticity of both epithelial cells and stromal cells. Although Snail is a transcriptional factor involved in the Epithelial-Mesenchymal ...
  • Santiago, Llipsy; Gil Gómez, Gabriel; Garrido, Marta; Peña, Raúl; Pardo, Julián (Elsevier, 2020)
    If not properly regulated, the inflammatory immune response can promote carcinogenesis, as evident in colorectal cancer (CRC). Aiming to gain mechanistic insight into the link between inflammation and CRC, we perform ...
  • Larriba, María Jesús; Casado Vela, Juan; Pendás Franco, Natalia; Peña, Raúl; García de Herreros, Antonio; Berciano, María Teresa; Lafarga, Miguel; Casal, José Ignacio; Muñoz, Alberto (Public Library of Science (PLoS), 2010)
    Background: The transcription factor Snail1 induces epithelial-to-mesenchymal transition (EMT), a process responsible for the acquisition of invasiveness during tumorigenesis. Several transcriptomic studies have ...
  • Mateu Jiménez, Mercè, 1990-; Fermoselle Pérez, Clara, 1985-; Rojo, Federico; Mateu de Antonio, Francisco Javier; Peña, Raúl; Urtreger, Alejandro J.; Diament, Miriam J.; Joffé, Elisa D. Bal de Kier; Pijuan Andujar, Lara; García de Herreros, Antonio; Barreiro Portela, Esther (Bentham Science Publishers, 2016)
    Lung cancer (LC) remains the leading cause of cancer mortality worldwide, and non-small cell LC (NSCLC) represents 80% of all LC. Oxidative stress and inflammation, autophagy, ubiquitin-proteasome system, nuclear factor ...
  • Alba-Castellón, Lorena; Batlle, Raquel; Francí, Clara; Fernández Aceñero, María Jesús; Mazzolini, Rocco; Peña, Raúl; Loubat, Jordina; Alameda Quitllet, Francisco; Rodríguez, Rufo; Curto, Josué; Albanell, Joan; Muñoz, Alberto; Bonilla, Félix; Casal, José Ignacio; Rojo, Federico; García de Herreros, Antonio (Elsevier, 2014)
    Snail1 transcriptional repressor is a major inducer of epithelial-to mesenchymal transition but is very limitedly expressed in adult animals. We have previously demonstrated that Snail1 is required for the maintenance of ...
  • Loubat Casanovas, Jordina, 1982-; Peña, Raúl; Gonzàlez Busqué, Núria, 1980-; Alba Castellón, Lorena, 1984-; Rosell, Santi; Francí i Carreté, Clara; Navarro Medrano, Pilar; García de Herreros, Antonio (Impact Journals, 2016)
    The Snail1 transcriptional factor is required for correct embryonic development, yet its expression in adult animals is very limited and its functional roles are not evident. We have now conditionally inactivated Snail1 ...
  • Lambies Barjau, Guillem, 1990-; Miceli, Martina; Martínez-Guillamon, Catalina; Olivera-Salguero, Rubén; Peña, Raúl; Frías, Carolina-Paola; Calderón, Irene; Atanassov, Boyko S.; Dent, Sharon Y.R.; Arribas, Joaquín; García de Herreros, Antonio; Díaz Cortés, Víctor Manuel, 1956- (American Association for Cancer Research (AACR), 2019)
    In cancer cells, epithelial-to-mesenchymal transition (EMT) is controlled by Snail1, a transcriptional factor also required for the activation of cancer-associated fibroblasts (CAF). Snail1 is short-lived in normal epithelial ...

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