Browsing by Author "Paetzold, Bernhard, 1981-"

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  • Characterization of different alginate lyases for dissolving Pseudomonas aeruginosa biofilms
    Blanco Cabra, Núria; Paetzold, Bernhard, 1981-; Ferrar, Tony; Mazzolini, Rocco; Torrents, Eduard; Serrano Pubull, Luis, 1982-; Lluch-Senar, Maria 1982- (Nature Research, 2020)
    Aggregates of Pseudomonas aeruginosa form a protective barrier against antibiotics and the immune system. These barriers, known as biofilms, are associated with several infectious diseases. One of the main components of ...
  • Engineering a genome-reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo
    Garrido, Victoria; Piñero-Lambea, Carlos; Rodriguez-Arce, Irene; Paetzold, Bernhard, 1981-; Ferrar, Tony; Weber, Marc; Garcia Ramallo, Eva; Gallo López, Carolina, 1984-; Collantes, María; Peñuelas, Iván; Serrano Pubull, Luis, 1982-; Grilló, María-Jesús; Lluch-Senar, Maria 1982- (Wiley Open Access, 2021)
    Bacteria present a promising delivery system for treating human diseases. Here, we engineered the genome-reduced human lung pathogen Mycoplasma pneumoniae as a live biotherapeutic to treat biofilm-associated bacterial ...
  • Engineering selectivity of Cutibacterium acnes phages by epigenetic imprinting
    Knödlseder, Nastassia; Nevot, Guillermo; Fábrega, María José; Mir-Pedrol, Júlia; Sanvicente-García, Marta; Campamà-Sanz, Nil; Paetzold, Bernhard, 1981-; Lood, Rolf; Güell Cargol, Marc, 1982- (Public Library of Science (PLoS), 2022)
    Cutibacterium acnes (C. acnes) is a gram-positive bacterium and a member of the human skin microbiome. Despite being the most abundant skin commensal, certain members have been associated with common inflammatory disorders ...
  • From dysbiosis to healthy skin: major contributions of Cutibacterium acnes to skin homeostasis
    Rozas, Miquel; Hart de Ruijter, Astrid; Fábrega, María José; Zorgani, Amine; Güell Cargol, Marc, 1982-; Paetzold, Bernhard, 1981-; Brillet, François (MDPI, 2021)
    Cutibacterium acnes is the most abundant bacterium living in human, healthy and sebum-rich skin sites, such as the face and the back. This bacterium is adapted to this specific environment and therefore could have a major ...
  • Safety and efficacy of topically applied selected cutibacterium acnes strains over five weeks in patients with acne vulgaris: an open-label, pilot study
    Koraglan, Ante; Paetzold, Bernhard, 1981-; Pereira de Lima, Joao; Brüggemann, Holger; Tüting, Thomas; Schanze, Denny; Güell Cargol, Marc, 1982-; Gollnick, Harald (Society for Publication of Acta Dermato-Venereologica, 2019)
    Imbalance in skin microflora, particularly related to certain Cutibacterium acnes strains, may trigger acne. Application of non-acne-causing strains to the skin may modulate the skin microbiome and thereby lead to a reduction ...
  • Skin microbiome modulation induced by probiotic solutions
    Paetzold, Bernhard, 1981-; Willis, Jesse R.; Pereira de Lima, Joao; Knödlseder, Nastassia; Brüggemann, Holger; Quist, Sven Roy; Gabaldón Estevan, Juan Antonio, 1973-; Güell Cargol, Marc, 1982- (BioMed Central, 2019)
    Background: The skin is colonized by a large number of microorganisms, most of which are beneficial or harmless. However, disease states of skin have specific microbiome compositions that are different from those of healthy ...
  • Skin microbiome transplantation and manipulation: Current state of the art
    Callewaert, Chris; Knödlseder, Nastassia; Karoglan, Ante; Güell Cargol, Marc, 1982-; Paetzold, Bernhard, 1981- (Elsevier, 2021)
    Many skin conditions are associated with an imbalance in the skin microbiome. In recent years, the skin microbiome has become a hot topic, for both therapeutic and cosmetic purposes. The possibility of manipulating the ...

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