Browsing by Author "Montero, Maria Milagro"

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  • Aminoglycoside or polymyxin monotherapy for treating complicated urinary tract infections caused by extensively drug-resistant pseudomonas aeruginosa: a propensity score-adjusted and matched cohort study
    López Montesinos, Inmaculada; Gómez-Zorrilla, Silvia; Palacios-Baena, Zaira Raquel; Prim, Núria; Echeverría Esnal, Daniel; Gracia Arnillas, María Pilar; Montero, Maria Milagro; Duran Jordà, Xavier, 1974-; Sendra, Elena; Sorli Redó, M. Luisa; Güerri Fernández, Roberto; Padilla, Eduardo; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo; PROA PSMAR group (SpringerOpen, 2022)
    Introduction: extensively drug-resistant (XDR) Pseudomonas aeruginosa (PA) infections are difficult to treat. We aimed to compare aminoglycosides or polymyxin monotherapy versus other antibiotic regimens (carbapenems, ...
  • Ceftolozane-tazobactam: when, how and why using it?
    López Montesinos, Inmaculada; Montero, Maria Milagro; Sorli Redó, M. Luisa; Horcajada Gallego, Juan Pablo (Sociedad Española de Quimioterapia, 2021)
    Ceftolozane-tazobactam is currently the most active antipseudomonal agent, including multidrug-resistant extensively drug-resistant strains. Tazobactam provides additional activity against many extended-spectrum beta-lactamases ...
  • Clinical and economic burden of community-onset multidrug-resistant infections requiring hospitalization
    López Montesinos, Inmaculada; Domínguez-Guasch, A.; Gómez-Zorrilla, Silvia; Duran Jordà, Xavier, 1974-; Siverio, Ana; Arenas-Miras, María Del Mar; Montero, Maria Milagro; Sorli Redó, M. Luisa; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo (Elsevier, 2020)
    Objectives: To analyze the clinical and economic burden of community-acquired (CA) or community-onset healthcare-associated (COHCA) multidrug-resistant (MDR) infections requiring hospitalization. Methods: Case-control ...
  • Clinical profiles in renal patients with COVID-19
    Arenas Jiménez, María Dolores; Crespo Barrio, Marta; Pérez-Sáez, María José; Collado Nieto, Silvia; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Barbosa Puig, Francisco; Buxeda, Anna; Burballa Tàrrega, Carla, 1988-; Sans Atxer, Laia; Vázquez, Susana; Oliveras, Anna; Mir, Marisa; Outón González, Sara; Galceran Herrera, Isabel; Solà Porta, Eulàlia; Sierra Ochoa, Adriana; Barrios Barrera, Clara; Rodriguez García, Eva; Cao Baduell, Higinio (MDPI, 2020)
    The COVID-19 pandemic has led to frequent referrals to the emergency department on suspicion of this infection in maintenance hemodialysis (MHD) and kidney transplant (KT) patients. We aimed to describe their clinical ...
  • Colistin for the treatment of urinary tract infections caused by Extremely Drug-resistant pseudomonas aeruginosa: dose is critical
    Sorli Redó, M. Luisa; Luque Pardos, Sònia; Li, Jian; Campillo Ambrós, Núria; Danés, Marc; Montero, Maria Milagro; Segura, Concepción; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo (Elsevier, 2019)
    Objectives: Optimal dosage regimens of colistin for the treatment of urinary tract infections (UTI) are unknown. Colistimethate sodium (CMS), the inactive prodrug of colistin, is mainly excreted in urine and converts to ...
  • Colistin plus meropenem combination is synergistic in vitro Aagainst extensively drug-resistant pseudomonas aeruginosa, including high-risk clones
    Montero, Maria Milagro; Domene Ochoa, Sandra; López-Causapé, Carla; VanScoy, Brian; Luque Pardos, Sònia; Sorli Redó, M. Luisa; Campillo Ambrós, Núria; Padilla, Eduardo; Prim, Núria; Segura, Concepción; Pomar, Virginia; Rivera, Alba; Grau Cerrato, Santiago; Ambrose, Paul G.; Oliver, Antonio; Horcajada Gallego, Juan Pablo (Elsevier, 2019)
    Background: Extensively drug-resistant (XDR) Pseudomonas aeruginosa (P. aeruginosa) and particularly P. aeruginosa high-risk clones, are of growing concern because treatment options are limited. For years, colistin monotherapy ...
  • Colistin use in patients with chronic kidney disease: are we underdosing patients?
    Sorli Redó, M. Luisa; Luque Pardos, Sònia; Li, Jian; Rodríguez, Eva; Campillo Ambrós, Núria; Fernández, Xenia; Soldado, Jade; Domingo, Ignacio; Montero, Maria Milagro; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo (MDPI, 2019)
    Colistin is administered as its inactive prodrug colistimethate (CMS). Selection of an individualized CMS dose for each patient is difficult due to its narrow therapeutic window, especially in patients with chronic kidney ...
  • Comparison of Ceftolozane/Tazobactam infusion regimens in a hollow-fiber infection model against extensively drug-resistant pseudomonas aeruginosa isolates
    Montero, Maria Milagro; Domene Ochoa, Sandra; López-Causapé, Carla; López Montesinos, Inmaculada; Luque Pardos, Sònia; Sorli Redó, M. Luisa; Campillo Ambrós, Núria; Padilla, Eduardo; Prim, Núria; Ferrer Alapont, Lorena; Grau Cerrato, Santiago; Oliver, Antoni; Horcajada Gallego, Juan Pablo (ASM Press, 2022)
    The aim of this study was to compare the efficacy of intermittent (1-h), extended (4-h), and continuous ceftolozane-tazobactam (C/T) infusion against three extensively drug-resistant (XDR) sequence type (ST) 175 P. aeruginosa ...
  • COVID-19 in elderly kidney transplant recipients
    Crespo Barrio, Marta; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Burballa Tàrrega, Carla, 1988-; Vázquez, Susana; Mir, Marisa; Sierra Ochoa, Adriana; Collado Nieto, Silvia; Barrios Barrera, Clara; Rodriguez García, Eva; Sans Atxer, Laia; Barbosa Puig, Francisco; Cao Baduell, Higinio; Arenas Jiménez, María Dolores; Güerri Fernández, Roberto; Horcajada Gallego, Juan Pablo; Pascual Santos, Julio (Wiley, 2020)
    The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 ...
  • COVID-19 in grade 4-5 chronic kidney disease patients
    Collado Nieto, Silvia; Arenas Jiménez, María Dolores; Barbosa Puig, Francisco; Cao Baduell, Higinio; Montero, Maria Milagro; Villar García, Judit; Barrios Barrera, Clara; Rodriguez García, Eva; Sans Atxer, Laia; Sierra Ochoa, Adriana; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Coca, Armando; Maiques LLacer, José María; Güerri Fernández, Roberto; Horcajada Gallego, Juan Pablo; Crespo Barrio, Marta; Pascual Santos, Julio (Karger (S. Karger AG), 2020)
    Introduction: Chronic kidney disease (CKD) increases the risk of mortality during coronavirus disease 2019 (COVID-19) episodes, and some reports have underlined the high incidence and severity of this infection in dialysis ...
  • Daptomycin plus fosfomycin versus Daptomycin lone for methicillin-resistant staphylococcus aureus bacteremia and endocarditis: a randomized clinical trial
    Pujol, Miquel; Montero, Maria Milagro; Carratalà, Jordi; MRSA Bacteremia (BACSARM) Trial Investigators (Oxford University Press, 2021)
    Background: We aimed to determine whether daptomycin plus fosfomycin provides higher treatment success than daptomycin alone for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and endocarditis. Methods: A ...
  • Effect of combination antibiotic empirical therapy on mortality in neutropenic cancer patients with pseudomonas aeruginosa pneumonia
    Albasanz-Puig, Adaia; Montero, Maria Milagro; Gudiol, Carlota; IRONIC study group (MDPI, 2022)
    To assess the effect of combination antibiotic empirical therapy on 30-day case-fatality rate in neutropenic cancer patients with Pseudomonas aeruginosa (PA) bacteremic pneumonia. This was a multinational, retrospective ...
  • Evaluation of the host immune response assay SeptiCyte RAPID for potential triage of COVID-19 patients
    Montero, Maria Milagro; Hardy-Werbin, Max; Gonzalez-Gallardo, Soledad; Torres, Erica; Rueda, Rebeca; Arenas-Miras, María Del Mar; Arietta-Aldea, Itziar; Castañeda, Silvia; Gómez Junyent, Joan; Gómez-Zorrilla, Silvia; Guerri-Fernandez, Robert; Sánchez-Martínez, Francesca; López Montesinos, Inmaculada; Pelegrín, Iván; Sendra, Elena; Sorlí, Luisa; Villar García, Judit; Bellosillo Paricio, Beatriz; Horcajada Gallego, Juan Pablo (Nature Research, 2023)
    Tools for the evaluation of COVID-19 severity would help clinicians with triage decisions, especially the decision whether to admit to ICU. The aim of this study was to evaluate SeptiCyte RAPID, a host immune response assay ...
  • Frequency and severity of potential drug interactions in a cohort of HIV-infected patients Identified through a Multidisciplinary team
    Molas, Ema; Luque Pardos, Sònia; Retamero, A.; Echeverría Esnal, Daniel; Guelar Grinberg, Ana; Montero, Maria Milagro; Güerri Fernández, Roberto; Sorli Redó, M. Luisa; Lerma-Chippirraz, Elisabet; Villar García, Judit; Knobel Freud, Hernando (Taylor & Francis (Routledge), 2018)
    OBJECTIVES: Interactions between antiretroviral treatment (ART) and comedications are a concern in HIV-infected patients. This study aimed to determine the frequency and severity of potential drug-drug interactions (PDDIs) ...
  • High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement
    Montero, Maria Milagro; Mir Fontana, M. Luisa; Sulleiro, Elena; Avalos Esquivel, J.L.; García López, E.; Molina-Morant, D.; López Montesinos, Inmaculada; Sorli Redó, M. Luisa; Veliz Espinosa, G.; Mounteis Oliva, E.; Crespo Barrio, Marta; Monge, I.; Horcajada Gallego, Juan Pablo; Grau Cerrato, Santiago; Pascual Santos, Julio (Elsevier, 2019)
    There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was ...
  • Impact of a nosocomial COVID-19 outbreak on a non-COVID-19 nephrology ward during the first wave of the pandemic in Spain
    Montero, Maria Milagro; Hidalgo López, Carlota; López Montesinos, Inmaculada; Sorli Redó, M. Luisa; Barrufet González, Cristina; Villar García, Judit; Güerri Fernández, Roberto; Herranz, Milagros; Crespo Barrio, Marta; Arenas Jiménez, María Dolores; Pascual Santos, Julio; González Juanes, Cristina; Horcajada Gallego, Juan Pablo (MDPI, 2021)
    Introduction: The aim of this study was to analyze a nosocomial coronavirus disease 2019 (COVID-19) outbreak that occurred on a polyvalent non-COVID-19 ward at a tertiary care university hospital in Spain during the first ...
  • Impact of antibiotic resistance on outcomes of neutropenic cancer patients with Pseudomonas aeruginosa bacteraemia (IRONIC study): study protocol of a retrospective multicentre international study
    Albasanz-Puig, Adaia; Montero, Maria Milagro; Carratalà, Jordi; IRONIC study group (BMJ Publishing Group, 2019)
    INTRODUCTION: Pseudomonas aeruginosa (PA) has historically been one of the major causes of severe sepsis and death among neutropenic cancer patients. There has been a recent increase of multidrug-resistant PA (MDRPA) ...
  • Impact of ceftolozane/tazobactam concentrations in continuous infusion against extensively drug-resistant Pseudomonas aeruginosa isolates in a hollow-fiber infection model
    Montero, Maria Milagro; Domene Ochoa, Sandra; López-Causapé, Carla; Luque Pardos, Sònia; Sorlí, Luisa; Campillo Ambrós, Núria; Padilla, Eduardo; Prim, Núria; Ferrer Alapont, Lorena; Angulo-Brunet, Ariadna; Grau Cerrato, Santiago; Oliver, Antonio; Horcajada Gallego, Juan Pablo (Nature Research, 2021)
    Ceftolozane/tazobactam (C/T) has emerged as a potential agent for the treatment of extensively drug-resistant (XDR) Pseudomonas aeruginosa infections. As it is a time-dependent antimicrobial, prolonged infusion may help ...
  • Impact of colistin plasma levels on the clinical outcome of patients with infections caused by extremely drug-resistant Pseudomonas aeruginosa
    Sorli Redó, M. Luisa; Luque Pardos, Sònia; Segura, Concepción; Campillo Ambrós, Núria; Montero, Maria Milagro; Esteve, Erika; Herrera, Sabina; Benito, Natividad; Álvarez Lerma, Francisco; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo (BioMed Central, 2017)
    Background: Colistin has a narrow therapeutic window with nephrotoxicity being the major dose-limiting adverse effect. Currently, the optimal doses and therapeutic plasma levels are unknown. Methods: Prospective observational ...
  • Multinational case-control study of risk factors for the development of late invasive pulmonary aspergillosis following kidney transplantation
    López-Medrano, Francisco; Pérez-Sáez, María José; Montero, Maria Milagro; Pascual Santos, Julio; Horcajada Gallego, Juan Pablo; Aguado, José María (Elsevier, 2018)
    OBJECTIVES: To assess the risk factors for development of late-onset invasive pulmonary aspergillosis (IPA) after kidney transplantation (KT). METHODS: We performed a multinational case-control study that retrospectively ...