Browsing by Author "Martín García, Elena, 1975-"

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  • Chung, Paul Chu Sin; Keyworth, Helen L.; Martín García, Elena, 1975-; Charbogne, Pauline; Darcq, Emmanuel; Bailey, Alexis; Filliol, Dominique; Matifas, Audrey; Scherrer, Grégory; Ouagazzal, Abdel-Mouttalib; Gaveriaux-Ruff, Claire; Befort, Katia; Maldonado, Rafael, 1961-; Kitchen, Ian; Kieffer, Brigitte L. (Elsevier, 2015)
    BACKGROUND: The delta opioid receptor (DOR) is broadly expressed throughout the nervous system; it regulates chronic pain, emotional responses, motivation, and memory. Neural circuits underlying DOR activities have been ...
  • Plaza-Zabala, Ainhoa, 1982-; Flores de los Heros, África, 1985-; Martín García, Elena, 1975-; Saravia, Rocío; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Nature Publishing Group, 2013)
    Hypocretin/orexin signaling is critically involved in relapse to drug-seeking behaviors. In this study, we investigated the involvement of the hypocretin system in the reinstatement of nicotine-seeking behavior induced by ...
  • Navarro-Romero, Alba; Vázquez-Oliver, Anna; Gomis González, Maria; Garzón-Montesinos, Carlos; Falcón-Moya, Rafael; Pastor, Antonio; Martín García, Elena, 1975-; Pizarro Lozano, Mª Nieves; Busquets Garcia, Arnau, 1985-; Revest, Jean-Michel; Piazza, Pier Vincenzo; Bosch, Fatima; Dierssen, Mara; Torre Fornell, Rafael de la; Rodríguez-Moreno, Antonio; Maldonado, Rafael, 1961-; Ozaita Mintegui, Andrés, 1969- (Elsevier, 2019)
    Intellectual disability is the most limiting hallmark of Down syndrome, for which there is no gold-standard clinical treatment yet. The endocannabinoid system is a widespread neuromodulatory system involved in multiple ...
  • Martín García, Elena, 1975-; Bourgoin, Lucie; Cathala, Adeline; Kasanetz, Fernando; Mondesir, Miguel; Gutiérrez-Rodríguez, Ana; Reguero, Leire; Fiancette, Jean-François; Grandes, Pedro; Spampinato, Umberto; Maldonado, Rafael, 1961-; Piazza, Pier Vincenzo; Marsicano, Giovanni; Deroche-Gamonet, Véronique (Nature Publishing Group, 2016)
    The type 1 cannabinoid receptor (CB1) modulates numerous neurobehavioral processes and is therefore explored as a target for the treatment of several mental and neurological diseases. However, previous studies have ...
  • Rodríguez-Arias, Marta; Montagud-Romero, Sandra; Rubio-Araiz, Ana; Aguilar Morón, María A.; Martín García, Elena, 1975-; Cabrera Ortega, Roberto; Maldonado, Rafael, 1961-; Porcu, Francesca; Colado, María Isabel; Miñarro, José (Wiley, 2017)
    Social stress in adulthood enhances cocaine self-administration, an effect that has been related with an increase in extracellular signal-regulated kinase and p38α mitogen-activated protein kinase phosphorylation. A ...
  • Planagumà, Jesús; Haselmann, Holger; Mannara, Francesco; Petit-Pedrol, Mar; Grünewald, Benedikt; Aguilar, Esther; Röpke, Luise; Martín García, Elena, 1975-; Titulaer, Maarten J.; Jercog, Pablo; Graus, Francesc; Maldonado, Rafael, 1961-; Geis, Christian; Dalmau, Josep (Wiley, 2016)
    OBJECTIVE: To demonstrate that ephrin-B2 (the ligand of EphB2 receptor) antagonizes the pathogenic effects of patients' N-methyl-D-aspartate receptor (NMDAR) antibodies on memory and synaptic plasticity. METHODS: One hundred ...
  • Mancino, Samantha, 1987-; Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Gutiérrez Martos, Miriam; Martín García, Elena, 1975-; Pucci, Mariangela; Falconi, Anastasia; D'Addario, Claudio; Maccarrone, Mauro; Maldonado, Rafael, 1961- (Nature Publishing Group, 2015)
    An increasing perspective conceptualizes obesity and overeating as disorders related to addictive-like processes that could share common neurobiological mechanisms. In the present study, we aimed at validating an animal ...
  • Burokas, Aurelijus, 1982-; Martín García, Elena, 1975-; Espinosa-Carrasco, José; Erb, Ionas; McDonald, Jerome; Notredame, Cedric; Dierssen, Mara; Maldonado, Rafael, 1961- (Wiley-Blackwell, 2018)
    A major problem in treating obesity is the high rate of relapse to abnormal food-taking habits after maintaining an energy balanced diet. Alterations of eating behavior such as compulsive-like behavior and lack of self-control ...
  • Martín García, Elena, 1975-; Fernández Castillo, Noelia; Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Sánchez-Mora, Cristina; Casas, Miguel; Ribasés, Marta; Cormand, Bru; Maldonado, Rafael, 1961- (Wiley, 2015)
    Frustration represents a particular aspect of the addictive process that is related to loss of control when the expected reward is not obtained. We aim to study the consequences of frustrated expected reward on gene ...
  • Robledo, Patricia, 1958-; Martín García, Elena, 1975-; Aso Pérez, Ester; Maldonado, Rafael, 1961- (Bentham Science Publishers, 2014)
    The pathophysiological mechanisms underlying depression are still poorly understood. An initial hypothesis postulated to explain the substrates of depression was based on the involvement of monoaminergic systems. This early ...
  • Busquets Garcia, Arnau, 1985-; Gomis González, Maria; Salgado Mendialdúa, Victòria; Galera López, Lorena; Puighermanal Puigvert, Emma, 1983-; Martín García, Elena, 1975-; Maldonado, Rafael, 1961-; Ozaita Mintegui, Andrés, 1969- (Nature Publishing Group, 2017)
    Cannabis affects cognitive performance through the activation of the endocannabinoid system, and the molecular mechanisms involved in this process are poorly understood. Using the novel object-recognition memory test in ...
  • Planagumà, Jesús; Leypoldt, Frank; Mannara, Francesco; Gutiérrez Cuesta, Javier; Martín García, Elena, 1975-; Aguilar, Esther; Titulaer, Maarten J.; Petit-Pedrol, Mar; Jain, Ankit; Balice-Gordon, Rita; Lakadamyali, Melike; Graus, Francesc; Maldonado, Rafael, 1961-; Dalmau, Josep (Oxford University Press, 2015)
    Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric disorder that associates with prominent memory and behavioural deficits. Patients' antibodies react with the N-terminal domain of the ...
  • Plaza-Zabala, Ainhoa, 1982-; Martín García, Elena, 1975-; Lecea, Luis de; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Society for Neuroscience, 2010)
    Emerging evidence suggests that the hypocretinergic system is involved in addictive behavior. In this study, we investigated the role of these hypothalamic neuropeptides in anxiety-like responses of nicotine and stress-induced ...
  • Martín García, Elena, 1975-; Mannara, Francesco; Gutiérrez Cuesta, Javier; Sabater, Lidia; Dalmau, Josep; Maldonado, Rafael, 1961-; Graus, Francesc (Elsevier, 2013)
    The role of antibodies against the P/Q type voltage-gated calcium channels (VGCC-ab) in the pathogenesis of paraneoplastic cerebellar degeneration (PCD) and lung cancer is unclear. We evaluated in mice the effect of ...
  • Mancino, Samantha, 1987- (Universitat Pompeu Fabra, 2016-01-22)
    The increase incidence of obesity and eating disorders represents a major health problem in developed countries. The low rate of success of treatments to prevent or reverse obesity, and overeating that causes it, highlights ...
  • Charbogne, Pauline; Martín García, Elena, 1975-; Robledo, Patricia, 1958-; Maldonado, Rafael, 1961-; Kieffer, Brigitte L. (Elsevier, 2017)
    BACKGROUND: Mu opioid receptors (MORs) are central to pain control, drug reward, and addictive behaviors, but underlying circuit mechanisms have been poorly explored by genetic approaches. Here we investigate the contribution ...
  • Berrendero Díaz, Fernando, 1971-; Robledo, Patricia, 1958-; Trigo i Rodríguez, Josep M.; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (Elsevier, 2010)
    Nicotine is the primary component of tobacco that maintains the smoking habit and develops addiction. The adaptive changes of nicotinic acetylcholine receptors produced by repeated exposure to nicotine play a crucial role ...
  • Burokas, Aurelijus, 1982- (Universitat Pompeu Fabra, 2013-11-15)
    The rapid increase of obesity has encouraged the study of the aetiology of eating disorders. Besides genetic, social and metabolic factors, obesity is caused by over-eating and has high rate of relapse to abnormal food-taking ...
  • Malviya, Manish; Mannara, Francesco; Martín García, Elena, 1975-; Maldonado, Rafael, 1961-; Goebels, Norbert (Wiley, 2017)
    Objective: Autoimmune encephalitis is most frequently associated with anti-NMDAR autoantibodies. Their pathogenic relevance has been suggested by passive transfer of patients' cerebrospinal fluid (CSF) in mice in vivo. We ...
  • Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (Wiley-Blackwell, 2012)
    One aspect of the addictive process that has not been thoroughly investigated is the consequence of the frustrated state occurring when the drug is not available. The present study aimed to validate a novel operant model ...