Browsing by Author "Martín García, Elena, 1975-"

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  • Chung, Paul Chu Sin; Keyworth, Helen L.; Martín García, Elena, 1975-; Charbogne, Pauline; Darcq, Emmanuel; Bailey, Alexis; Filliol, Dominique; Matifas, Audrey; Scherrer, Grégory; Ouagazzal, Abdel-Mouttalib; Gaveriaux-Ruff, Claire; Befort, Katia; Maldonado, Rafael, 1961-; Kitchen, Ian; Kieffer, Brigitte L. (Elsevier, 2015)
    BACKGROUND: The delta opioid receptor (DOR) is broadly expressed throughout the nervous system; it regulates chronic pain, emotional responses, motivation, and memory. Neural circuits underlying DOR activities have been ...
  • Plaza-Zabala, Ainhoa, 1982-; Flores de los Heros, África, 1985-; Martín García, Elena, 1975-; Saravia Santos, Rocio, 1988-; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Nature Publishing Group, 2013)
    Hypocretin/orexin signaling is critically involved in relapse to drug-seeking behaviors. In this study, we investigated the involvement of the hypocretin system in the reinstatement of nicotine-seeking behavior induced by ...
  • Domingo Rodriguez, Laura, 1992-; Ruiz de Azua, Iñigo; Domínguez, Eduardo; Senabre, Eric; Serra, Irene; Kummer, Sami; Navandar, Mohit; Baddenhausen, Sarah; Hofmann, Clementine; Andero, Raül; Gerber, Susanne; Navarrete, Marta; Dierssen, Mara; Lutz, Beat; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (Nature Research, 2020)
    Food addiction is linked to obesity and eating disorders and is characterized by a loss of behavioral control and compulsive food intake. Here, using a food addiction mouse model, we report that the lack of cannabinoid ...
  • Grau Cerrato, Santiago; Ferrández, Olivia; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (MDPI, 2021)
  • Martín García, Elena, 1975-; Vivori, Claudia, 1989-; Rogalska, Malgorzata; Herrero-Vicente, Jorge; Valcárcel, J. (Juan) (Cold Spring Harbor Laboratory Press (CSHL Press), 2021)
    The regulation of pre-mRNA processing has important consequences for cell division and the control of cancer cell proliferation, but the underlying molecular mechanisms remain poorly understood. We report that three splicing ...
  • Ruiz de Azua, Iñigo; Martín García, Elena, 1975-; Domingo Rodriguez, Laura, 1992-; Aparisi Rey, Alejandro; Pascual Cuadrado, Diego; Islami, Larglinda; Turunen, Petri; Remmers, Floortje; Lutz, Beat; Maldonado, Rafael, 1961- (Nature Research, 2021)
    Palatable food can promote overfeeding beyond homeostatic requirements, thereby constituting a major risk to obesity. Here, the lack of cannabinoid type 1 receptor (CB1) in dorsal telencephalic glutamatergic neurons ...
  • Navarro-Romero, Alba; Vázquez-Oliver, Anna; Gomis González, Maria, 1988-; Garzón-Montesinos, Carlos; Falcón-Moya, Rafael; Pastor, Antonio; Martín García, Elena, 1975-; Pizarro Lozano, Mª Nieves; Busquets Garcia, Arnau, 1985-; Revest, Jean-Michel; Piazza, Pier Vincenzo; Bosch, Fatima; Dierssen, Mara; Torre Fornell, Rafael de la; Rodríguez-Moreno, Antonio; Maldonado, Rafael, 1961-; Ozaita Mintegui, Andrés, 1969- (Elsevier, 2019)
    Intellectual disability is the most limiting hallmark of Down syndrome, for which there is no gold-standard clinical treatment yet. The endocannabinoid system is a widespread neuromodulatory system involved in multiple ...
  • Soldevila-Domenech, Natalia; Tío, Laura; Llorente Onaindia, Jone; Martín García, Elena, 1975-; Nebot Forcada, Pau; Torre Fornell, Rafael de la; Gurt, Alba; Maldonado, Rafael, 1961-; Monfort, Jordi; Covidmar Study Group (Frontiers, 2020)
    The effect of immunosuppressant treatments on the incidence of coronavirus disease (COVID-19) remains largely unknown. We studied the association between the pre-exposure to disease-modifying antirheumatic drugs (DMARDs) ...
  • Grau Cerrato, Santiago; Martín García, Elena, 1975-; Ferrández, Olivia; Martín, Raquel; Tejedor Vaquero, Sonia, 1988-; Gimeno, Ramón; Magri, Giuliana, 1978-; Maldonado, Rafael, 1961- (MDPI, 2022)
    The massive COVID-19 vaccine purchases made by high-income countries have resulted in important sample losses, mainly due to the complexity of their handling. Here, we evaluated the possibility of preserving the immunogenicity ...
  • Martín García, Elena, 1975-; Bourgoin, Lucie; Cathala, Adeline; Kasanetz, Fernando; Mondesir, Miguel; Gutiérrez-Rodríguez, Ana; Reguero, Leire; Fiancette, Jean-François; Grandes, Pedro; Spampinato, Umberto; Maldonado, Rafael, 1961-; Piazza, Pier Vincenzo; Marsicano, Giovanni; Deroche-Gamonet, Véronique (Nature Publishing Group, 2016)
    The type 1 cannabinoid receptor (CB1) modulates numerous neurobehavioral processes and is therefore explored as a target for the treatment of several mental and neurological diseases. However, previous studies have ...
  • Rodríguez-Arias, Marta; Montagud-Romero, Sandra; Rubio-Araiz, Ana; Aguilar Morón, María Asunción; Martín García, Elena, 1975-; Cabrera Ortega, Roberto; Maldonado, Rafael, 1961-; Porcu, Francesca; Colado, María Isabel; Miñarro, José (Wiley, 2017)
    Social stress in adulthood enhances cocaine self-administration, an effect that has been related with an increase in extracellular signal-regulated kinase and p38α mitogen-activated protein kinase phosphorylation. A ...
  • Planagumà, Jesús; Haselmann, Holger; Mannara, Francesco; Petit-Pedrol, Mar; Grünewald, Benedikt; Aguilar, Esther; Röpke, Luise; Martín García, Elena, 1975-; Titulaer, Maarten J.; Jercog, Pablo; Graus, Francesc; Maldonado, Rafael, 1961-; Geis, Christian; Dalmau, Josep (Wiley, 2016)
    OBJECTIVE: To demonstrate that ephrin-B2 (the ligand of EphB2 receptor) antagonizes the pathogenic effects of patients' N-methyl-D-aspartate receptor (NMDAR) antibodies on memory and synaptic plasticity. METHODS: One hundred ...
  • Mancino, Samantha, 1987-; Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Gutiérrez Martos, Miriam; Martín García, Elena, 1975-; Pucci, Mariangela; Falconi, Anastasia; D'Addario, Claudio; Maccarrone, Mauro; Maldonado, Rafael, 1961- (Nature Publishing Group, 2015)
    An increasing perspective conceptualizes obesity and overeating as disorders related to addictive-like processes that could share common neurobiological mechanisms. In the present study, we aimed at validating an animal ...
  • Burokas, Aurelijus, 1982-; Martín García, Elena, 1975-; Espinosa-Carrasco, José; Erb, Ionas; McDonald, Jerome; Notredame, Cedric; Dierssen, Mara; Maldonado, Rafael, 1961- (Wiley-Blackwell, 2018)
    A major problem in treating obesity is the high rate of relapse to abnormal food-taking habits after maintaining an energy balanced diet. Alterations of eating behavior such as compulsive-like behavior and lack of self-control ...
  • Martín García, Elena, 1975-; Fernández Castillo, Noelia; Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Sánchez-Mora, Cristina; Casas, Miguel; Ribasés, Marta; Cormand, Bru; Maldonado, Rafael, 1961- (Wiley, 2015)
    Frustration represents a particular aspect of the addictive process that is related to loss of control when the expected reward is not obtained. We aim to study the consequences of frustrated expected reward on gene ...
  • Robledo, Patricia, 1958-; Martín García, Elena, 1975-; Aso Pérez, Ester; Maldonado, Rafael, 1961- (Bentham Science Publishers, 2014)
    The pathophysiological mechanisms underlying depression are still poorly understood. An initial hypothesis postulated to explain the substrates of depression was based on the involvement of monoaminergic systems. This early ...
  • Maldonado, Rafael, 1961-; Calvé, Pablo; García Blanco, Alejandra; Domingo Rodriguez, Laura, 1992-; Senabre, Eric; Martín García, Elena, 1975- (Wiley, 2021)
    Recent progress in the genomics and epigenomics of addiction has contributed to improving our understanding of this complex mental disorder's etiology, filling the gap between genes, environment, and behavior. We review ...
  • Busquets Garcia, Arnau, 1985-; Gomis González, Maria, 1988-; Salgado Mendialdúa, Victòria; Galera López, Lorena; Puighermanal Puigvert, Emma, 1983-; Martín García, Elena, 1975-; Maldonado, Rafael, 1961-; Ozaita Mintegui, Andrés, 1969- (Nature Publishing Group, 2017)
    Cannabis affects cognitive performance through the activation of the endocannabinoid system, and the molecular mechanisms involved in this process are poorly understood. Using the novel object-recognition memory test in ...
  • Planagumà, Jesús; Leypoldt, Frank; Mannara, Francesco; Gutiérrez Cuesta, Javier; Martín García, Elena, 1975-; Aguilar, Esther; Titulaer, Maarten J.; Petit-Pedrol, Mar; Jain, Ankit; Balice-Gordon, Rita; Lakadamyali, Melike; Graus, Francesc; Maldonado, Rafael, 1961-; Dalmau, Josep (Oxford University Press, 2015)
    Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric disorder that associates with prominent memory and behavioural deficits. Patients' antibodies react with the N-terminal domain of the ...
  • Plaza-Zabala, Ainhoa, 1982-; Martín García, Elena, 1975-; Lecea, Luis de; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Society for Neuroscience, 2010)
    Emerging evidence suggests that the hypocretinergic system is involved in addictive behavior. In this study, we investigated the role of these hypothalamic neuropeptides in anxiety-like responses of nicotine and stress-induced ...