Browsing by Author "Julià, Antonio"

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  • Aterido Ballonga, Adrià, 1990-; Cañete Crespillo, Juan de Dios; Tornero, Jesús; Blanco, Francisco; Fernández-Gutiérrez, Benjamín; Pérez-García, Carolina; Alperiz, Mercedes; Olivé, Alex; Corominas, Héctor; Martínez-Taboada, Víctor; González-Alvaro, Isidoro; Fernández-Nebro, Antonio; Erra, Alba; López Lasanta, María; López Corbeto, Mireia; Palau, Núria; Marsal, Sara; Julià, Antonio (Frontiers, 2019)
    Background: Rheumatoid arthritis (RA) is the most frequent autoimmune disease involving the joints. Although anti-TNF therapies have proven effective in the management of RA, approximately one third of patients do not show ...
  • Aterido Ballonga, Adrià, 1990-; Pérez-García, Carolina; Julià, Antonio (BMJ Publishing Group, 2019)
    OBJECTIVE: Psoriatic arthritis (PsA) is a chronic inflammatory arthritis affecting up to 30% of patients with psoriasis (Ps). To date, most of the known risk loci for PsA are shared with Ps, and identifying disease-specific ...
  • Julià, Antonio; Bonàs-Guarch, Silvia; Mercader Bigas, Josep Maria; Torrents, David; Fernández-Nebro, Antonio (BioMed Central, 2018)
    Background: Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease with a complex genetic inheritance. Genome-wide association studies (GWAS) have significantly increased the number of significant loci ...
  • Aterido Ballonga, Adrià, 1990-; Julià, Antonio; Ferrándiz, Carlos; Puig, Lluís; Fonseca, Eduardo; Fernández-López, Emilia; Dauden, Esteban; Sánchez-Carazo, José Luís; López-Estebaranz, José Luís; Moreno-Ramírez, David; Vanaclocha, Francisco; Herrera, Enrique; Cueva, Pablo de la; Dand, Nick; Palau, Núria; Alonso, Arnald; López-Lasanta, María; Tortosa, Raül; García-Montero, Andrés; Codó, Laia; Gelpí, Josep Lluís; Bertranpetit, Jaume, 1952-; Absher, Devin; Capon, Francesca; Myers, Richard M.; Barker, Jonathan N.; Marsal, Sara (Elsevier, 2016)
    Psoriasis is a chronic inflammatory disease with a complex genetic architecture. To date, the psoriasis heritability is only partially explained. However, there is increasing evidence that the missing heritability in ...
  • Julià, Antonio; López-Lasanta, María; Blanco, Francisco; Gómez, Antonio; Haro, Isabel; Mas, Antonio Juan; Erra, Alba; García Vivar, María Luz; Monfort Faure, Jorge; Sánchez-Fernández, Simón; González, Isidoro; Alperi, Mercedes; Castellanos-Moreira, Raúl; Fernández-Nebro, Antonio; Díaz Torne, César; Palau, Núria; Lastra Borràs, Raquel; Lladós, Jordi; Sanmartí, Raimon; Marsal, Sara (BioMed Central, 2021)
    Background: blocking of the Tumor Necrosis Factor (TNF) activity is a successful therapeutic approach for 50-60% of rheumatoid arthritis (RA) patients. However, there are yet no biomarkers to stratify patients for anti-TNF ...
  • Julià, Antonio; Pérez-García, Carolina; Marsal, Sara (Elsevier, 2022)
    Background: rheumatoid arthritis (RA) is a chronic, immune-mediated inflammatory disease of the joints that has been associated with variation in the peripheral blood methylome. In this study, we aim to identify epigenetic ...
  • Schäfer, Samuel; Smelik, Martin; Sysoev, Oleg; Zhao, Yelin; Eklund, Desiré; Lilja, Sandra; Gustafsson, Mika; Heyn, Holger; Julià, Antonio; Kovács, István A.; Loscalzo, Joseph; Marsal Barril, Sara; Zhang, Huan; Li, Xinxiu; Gawel, Danuta; Wang, Hui; Benson, Mikael (BioMed Central, 2024)
    Background: Ineffective drug treatment is a major problem for many patients with immune-mediated inflammatory diseases (IMIDs). Important reasons are the lack of systematic solutions for drug prioritisation and repurposing ...
  • Avila Pedretti, Gabriela; Tornero, Jesús; Fernández-Nebro, Antonio; Blanco, Francisco; González-Alvaro, Isidoro; Cañete Crespillo, Juan de Dios; Maymó Guarch, Joan; Alperiz, Mercedes; Fernández-Gutiérrez, Benjamín; Olivé, Alex; Corominas, Héctor; Erra, Alba; Aterido Ballonga, Adrià, 1990-; López Lasanta, María; Tortosa, Raül; Julià, Antonio; Marsal, Sara (Public Library of Science, 2015)
    OBJECTIVE: Anti-TNF therapies have been highly efficacious in the management of rheumatoid arthritis (RA), but 25-30% of patients do not show a significant clinical response. There is increasing evidence that genetic ...

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