Browsing by Author "Ivančić, Dimitrije"

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  • Find and cut-and-transfer (FiCAT) mammalian genome engineering
    Pallarès-Masmitjà, Maria; Ivančić, Dimitrije; Mir-Pedrol, Júlia; Jaraba-Wallace, Jessica; Tagliani, Tommaso; Oliva Miguel, Baldomero; Rahmeh, Amal; Sánchez-Mejías, Avencia; Güell Cargol, Marc, 1982- (Nature Research, 2021)
    While multiple technologies for small allele genome editing exist, robust technologies for targeted integration of large DNA fragments in mammalian genomes are still missing. Here we develop a gene delivery tool (FiCAT) ...
  • INSERT-seq enables high-resolution mapping of genomically integrated DNA using Nanopore sequencing
    Ivančić, Dimitrije; Mir-Pedrol, Júlia; Jaraba-Wallace, Jessica; Rafel i Fontanals, Núria, 1954-; Sánchez-Mejías, Avencia; Güell Cargol, Marc, 1982- (BioMed Central, 2022)
    Comprehensive characterisation of genome engineering technologies is relevant for their development and safe use in human gene therapy. Short-read based methods can overlook insertion events in repetitive regions. We develop ...
  • Intein-mediated thyroid hormone biosensors: towards controlled delivery of hormone therapy
    Martí Baena, Quim; Pascuet Fontanet, Andreu; Berjaga Buisan, Tomas; Caravaca Rodríguez, Miriam; Puig Costa-Jussà, Jaume; Sánchez Mejías, Avencia; Ivančić, Dimitrije; Mogas Díez, Sira; Güell Cargol, Marc, 1982-; Macía, Javier (Frontiers, 2024)
    Although blood sampling and medical imaging are well-established techniques in clinical diagnostics, they often require long post-processing procedures. Fast and simple quantification of signaling molecules can enable ...

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