Browsing by Author "Hernández Llodrà, Silvia"

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  • Clinical interest of LMO2 testing for the diagnosis of aggressive large B-Cell lymphomas
    Vazquez de las Heras, Ivonne; Papaleo, Natalia; García, Eugenia; Salido Galeote, Marta; Salar Silvestre, Antonio; Hernández Llodrà, Silvia; Calvo Gonzalo, Xavier; Colomo Saperas, Luis Alberto (MDPI, 2020)
    MYC rearrangements usually confer aggressive biological behavior to large B-cell lymphomas. In this study, we aimed to evaluate the relevance of LMO2 detection to the clinical approach to these tumors. First, the ability ...
  • ERG overexpression plus SLC45A3 (prostein) and PTEN expression loss: Strong association of the triple hit phenotype with an aggressive pathway of prostate cancer progression
    Hernández Llodrà, Silvia; Juanpere, Nuria; Muga, Silvia de; Lorenzo Perez, Marta; Gil Ortega, Joan; Font Tello, Alba 1990-; Agell, Laia; Albero-González, Raquel; Segalés, Laura; Merino, José; Serrano, Laia; Fumadó Ciutat, Lluis; Cecchini Rosell, Lluís; Lloreta, Josep, 1958- (Impact Journals, 2017)
    TMPRSS2 and SLC45A3 rearrangements may coexist in the same tumor. ERG rearrangements and PTEN loss are concomitant events in prostate cancer (PrCa), and can cooperate in progression. We have reported that mRNA expression ...
  • ERG rearrangements and PTEN loss in prostate cancer
    Font Tello, Alba 1990- (Universitat Pompeu Fabra, 2018-01-24)
    Prostate cancer (PrCa) is a highly heterogeneous disease and its prognosis, diagnosis and management are still controversial. ERG rearrangements and PTEN loss are frequent and concomitant events in a subset of PrCa. The ...
  • Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
    Segalés Tañà, Laura, 1994-; Juanpere, Nuria; Gallarín, Nerea; Lorenzo Perez, Marta; López Martos, David; Perera Bel, Júlia; Rodriguez-Vida, Alejo; Fumadó Ciutat, Lluis; Cecchini Rosell, Lluís; Bellmunt Molins, Joaquim, 1959-; Lloreta, Josep, 1958-; Hernández Llodrà, Silvia (Springer, 2024)
    The impact of tumor focality on prostate cancer (PCa) prognosis has been addressed in several studies with conflicting results. Tumor foci from multifocal (MF) PCa can show highly heterogeneous molecular features. Our aim ...
  • SPOP and CHD1 alterations in prostate cancer: Relationship with PTEN loss, tumor grade, perineural infiltration, and PSA recurrence
    Hernández Llodrà, Silvia; Segalés Tañà, Laura, 1994-; Juanpere, Nuria; Lorenzo Perez, Marta; Salido Galeote, Marta; Nonell Mazelon, Lara, 1972-; López Martos, David; Rodríguez-Vida, Alejo; Bellmunt Molins, Joaquim, 1959-; Fumadó Ciutat, Lluis; Cecchini Rosell, Lluís; Lloreta, Josep, 1958- (Wiley, 2021)
    Background: In the non-ETS fusion of prostate cancer (PCa) pathway, SPOP mutations emerge as a distinct oncogenic driver subclass. Both SPOP downregulation and mutation can lead to SPOP target stabilization promoting ...
  • The impact of mutational clonality in predicting the response to immune checkpoint inhibitors in advanced urothelial cancer
    Boll, Lilian Marie; Perera Bel, Júlia; Rodriguez-Vida, Alejo; Arpí Llucià, Oriol; Rovira, Ana; Juanpere, Nuria; Vázquez Montes de Oca, Sergio; Hernández Llodrà, Silvia; Lloreta, Josep, 1958-; Albà Soler, Mar; Bellmunt Molins, Joaquim, 1959- (Nature Research, 2023)
    Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment and can result in complete remissions even at advanced stages of the disease. However, only a small fraction of patients respond to the treatment. To ...
  • Transcriptomic analysis of micropapillary high grade T1 urothelial bladder cancer
    Bowden, Michaela; Nadal, Rosa; Zhou, Chensheng W.; Werner, Lillian; Barletta, Justine A.; Juanpere, Nuria; Lloreta, Josep, 1958-; Hernández Llodrà, Silvia; Morote, Juan; Torres, Inés de; Orsola, Anna; Cejas, Paloma; Long, Henry; Bellmunt Molins, Joaquim, 1959- (Nature Research, 2020)
    No consensus currently exist on the optimal treatment of patients with high-risk nonmuscle invasive (HGT1) micropapillary variant of bladder cancer (MPBC). Transcripsome analysis may allow stratification of MPBC-HGT1 ...

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