Browsing by Author "Hartl, F. Ulrich"

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  • Lamond, Angus I.; Uhlen, Mathias; Horning, Stevan; Makarov, Alexander; Robinson, Carol V.; Serrano Pubull, Luis, 1982-; Hartl, F. Ulrich; Baumeister, Wolfgang; Werenskiold, Anne Katrin; Andersen, Jens S.; Vorm, Ole; Linial, Michal; Aebersold, Ruedi; Mann, Matthias (American Society for Biochemistry and Molecular Biology (ASBMB), 2012)
    The term "proteomics" encompasses the large-scale detection and analysis of proteins and their post-translational modifications. Driven by major improvements in mass spectrometric instrumentation, methodology, and data ...
  • Vecchi, Giulia; Sormanni, Pietro; Mannini, Benedetta; Vandelli, Andrea; Tartaglia, Gian Gaetano; Dobson, Christopher M.; Hartl, F. Ulrich; Vendruscolo, Michele (National Academy of Sciences, 2020)
    To function effectively proteins must avoid aberrant aggregation, and hence they are expected to be expressed at concentrations safely below their solubility limits. By analyzing proteome-wide mass spectrometry data of ...
  • Hosp, Fabian; Gutiérrez Ángel, Sara; Schaefer, Martin H.; Cox, Jürgen; Meissner, Felix; Hipp, Mark Steffen; Hartl, F. Ulrich; Klein, Rüdiger; Dudanova, Irina; Mann, Matthias (Elsevier, 2017)
    Aggregation of polyglutamine-expanded huntingtin exon 1 (HttEx1) in Huntington's disease (HD) proceeds from soluble oligomers to late-stage inclusions. The nature of the aggregates and how they lead to neuronal dysfunction ...

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