Browsing by Author "Griebel, Thasso"

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  • ChimPipe: Accurate detection of fusion genes and transcription-induced chimeras from RNA-seq data
    Rodríguez Martín, Bernardo; Palumbo, Emilio; Marco Sola, Santiago; Griebel, Thasso; Ribeca, Paolo; Alonso, Graciela; Rastrojo, Alberto; Aguado, Begoña; Guigó Serra, Roderic; Djebali, Sarah (BioMed Central, 2017)
    Background: Chimeric transcripts are commonly defined as transcripts linking two or more different genes in the genome, and can be explained by various biological mechanisms such as genomic rearrangement, read-through or ...
  • Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes
    Esteve-Codina, Anna; Soler Artigas, María; Dabad, Marc; Fernández Callejo, Marcos; Griebel, Thasso; Heath, Simon; Gut, Ivo Glynne; Ziegler-Heitbrock, Loems (Nature Research, 2021)
    Chronic obstructive pulmonary disease (COPD) is a destructive inflammatory disease and the genes expressed within the lung are crucial to its pathophysiology. We have determined the RNAseq transcriptome of bronchial brush ...
  • Modelling and simulating generic RNA-Seq experiments with the flux simulator
    Griebel, Thasso; Zacher, Benedikt; Ribeca, Paolo; Raineri, Emanuele; Lacroix, Vincent; Guigó Serra, Roderic; Sammeth, Michael (Oxford University Press, 2012)
    High-throughput sequencing of cDNA libraries constructed from cellular RNA complements (RNA-Seq) naturally provides a digital quantitative measurement for every expressed RNA molecule. Nature, impact and mutual interference ...