Browsing by Author "Galindo-Campos, Miguel A."

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  • Lutfi, Nura; Galindo-Campos, Miguel A.; Yélamos López, José (MDPI, 2021)
    The DNA damage response (DDR) maintains the stability of a genome faced with genotoxic insults (exogenous or endogenous), and aberrations of the DDR are a hallmark of cancer cells. These cancer-specific DDR defects present ...
  • Hardy-Werbin, Max; del Rey-Vergara, Raúl; Galindo-Campos, Miguel A.; Moliner Jiménez, Laura; Arriola Aperribay, Edurne (MDPI, 2019)
    Small cell lung cancer (SCLC) is the most aggressive type of lung cancer. The different systemic treatment approaches attempted in the last 35 years have not improved overall survival in the advanced stage. Targeted therapies ...
  • Navarro, Judith; Gozalbo-López, Beatriz; Méndez, Andrea C.; Dantzer, Françoise; Schreiber, Valérie; Martínez, Carlos; Arana, David M.; Farrés, Jordi; Revilla-Nuin, Beatriz; Bueno, María F.; Ampurdanés, Coral; Galindo-Campos, Miguel A.; Knobel, Philip A.; Segura-Bayona, Sandra; Martín Caballero, Juan; Stracker, Travis; Aparicio, Pedro; Del Val, Margarita; Yélamos López, José (Nature Publishing Group, 2017)
    The maintenance of T-cell homeostasis must be tightly regulated. Here, we have identified a coordinated role of Poly(ADP-ribose) polymerase-1 (PARP-1) and PARP-2 in maintaining T-lymphocyte number and function. Mice bearing ...
  • Ali, Syed O.; Khan, Farhaan A.; Galindo-Campos, Miguel A.; Yélamos López, José (e-Century Publishing, 2016)
    Poly(ADP-ribosyl)ation (PARylation) is a widespread and highly conserved post-translational modification catalysed by a large family of enzymes called poly(ADP-ribose) polymerases (PARPs). PARylation plays an essential ...

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