Browsing by Author "Fernández Sanlés, Alba, 1988-"

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  • Association between DNA methylation and coronary heart disease or other atherosclerotic events: A systematic review
    Fernández Sanlés, Alba, 1988-; Sayols, Sergi; Subirana Cachinero, Isaac; Dégano, Irene R.; Elosua Llanos, Roberto (Elsevier, 2017)
    BACKGROUND AND AIMS: The aim of this study was to perform a systematic review of the association between DNA methylation and coronary heart disease (CHD) or related atherosclerotic traits. METHODS: A systematic review was ...
  • Association between long-term air pollution exposure and DNA methylation: The REGICOR study
    Sayols, Sergi; Fernández Sanlés, Alba, 1988-; Prats Uribe, Albert; Subirana Cachinero, Isaac; Plusquin, Michelle; Künzli, Nino; Marrugat de la Iglesia, Jaume; Basagaña Flores, Xavier; Elosua Llanos, Roberto (Elsevier, 2019)
    INTRODUCTION: Limited evidence suggests that epigenetic mechanisms may partially mediate the adverse effects of air pollution on health. Our aims were to identify new genomic loci showing differential DNA methylation ...
  • DNA methylation and gene expression integration in cardiovascular disease
    Palou Márquez, Guillermo; Subirana Cachinero, Isaac; Nonell Mazelón, Lara; Fernández Sanlés, Alba, 1988-; Elosua Llanos, Roberto (BioMed Central, 2021)
    Background: The integration of different layers of omics information is an opportunity to tackle the complexity of cardiovascular diseases (CVD) and to identify new predictive biomarkers and potential therapeutic targets. ...
  • DNA methylation biomarkers of myocardial infarction and cardiovascular disease
    Fernández Sanlés, Alba, 1988-; Sayols Baixeras, Sergi, 1988-; Subirana Cachinero, Isaac; Sentí Clapés, Mariano; Pérez-Fernández, Silvia; Castro de Moura, Manuel; Esteller, Manel; Marrugat de la Iglesia, Jaume; Elosua Llanos, Roberto (BioMed Central, 2021)
    Background: The epigenetic landscape underlying cardiovascular disease (CVD) is not completely understood and the clinical value of the identified biomarkers is still limited. We aimed to identify differentially methylated ...
  • DNA methylation of MMPs and TIMPs in atherothrombosis process in carotid plaques and blood tissues
    Gallego-Fabrega, Cristina; Cullell, Natalia; Soriano Tarraga, Carolina; Carrera, Caty; Torres-Aguila, Nuria P.; Muiño, Elena; Cárcel-Márquez, Jara; Castro de Moura, Manuel; Fernández Sanlés, Alba, 1988-; Esteller, Manel; Elosua Llanos, Roberto; Jiménez Conde, Jordi; Roquer, Jaume; Montaner, Joan; Krupinski, Jerzy; Fernández-Cadenas, Israel (Impact Journals, 2020)
    Background and purpose: Polymorphisms and serum levels of Matrix Metalloproteinases (MMP) and Tissue Inhibitor of Metalloproteinases (TIMP) have been studied with regard to atheromatous plaques and ischemic stroke, while ...
  • DNA methylation, cardiovascular risk and myocardial infarction : an epigenome-wide approach
    Fernández Sanlés, Alba, 1988- (Universitat Pompeu Fabra, 2020-01-31)
    Cardiovascular diseases are a major challenge for public health. DNA methylation is a mechanism regulating gene expression, and it is linked to complex diseases and related traits. Therefore, it is a potential source of ...
  • Epigenomic assessment of cardiovascular disease risk and interactions with traditional risk metrics
    Westerman, Kenneth; Fernández Sanlés, Alba, 1988-; Patil, Prasad; Sebastiani, Paola; Jacques, Paul; Starr, John M.; Deary ,Ian J.; Liu, Qing; Liu, Simi; Elosua Llanos, Roberto; DeMeo, Dawn L; Ordovás, José M. (Wiley-Blackwell, 2020)
    Background Epigenome-wide association studies for cardiometabolic risk factors have discovered multiple loci associated with incident cardiovascular disease (CVD). However, few studies have sought to directly optimize a ...
  • High-density lipoprotein characteristics and coronary artery disease: a Mendelian randomization study
    Prats Uribe, Albert; Sayols Baixeras, Sergi, 1988-; Fernández Sanlés, Alba, 1988-; Subirana Cachinero, Isaac; Carreras-Torres, Robert; Vilahur, Gemma; Civeira, Fernando; Marrugat de la Iglesia, Jaume; Fitó Colomer, Montserrat; Hernáez, Álvaro; Elosua Llanos, Roberto (Elsevier, 2020)
    Background: To assess whether genetically determined quantitative and qualitative HDL characteristics were independently associated with coronary artery disease (CAD). Methods: We designed a two-sample multivariate Mendelian ...