Browsing by Author "Duran, Xavier"

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  • Attenuation of tumor burden in response to rucaparib in lung aAdenocarcinoma: the contribution of oxidative stress, apoptosis, and DNA damage
    Pérez-Peiró, Maria; Valentí-Serra, Paula; León-González, Blanca; Ampurdanés, Coral; Duran, Xavier; Yélamos, José; Barreiro Portela, Esther (MDPI, 2023)
    In cancer, overactivation of poly (ADPribose) polymerases (PARP) plays a relevant role in DNA repair. We hypothesized that treatment with the PARP inhibitor rucaparib may reduce tumor burden via several biological mechanisms ...
  • B cells and tertiary lymphoid structures influence survival in lung cancer patients with resectable tumors
    Tang, Jun; Ramis Cabrer, Daniel, 1993-; Curull Serrano, Víctor; Wang, Xuejie; Mateu Jiménez, Mercè, 1990-; Pijuan Andujar, Lara; Duran, Xavier; Qin, Liyun; Rodríguez-Fuster, Alberto; Aguiló Espases, Rafael; Barreiro Portela, Esther (MDPI, 2020)
    Immune profile of B and T cells and tertiary lymphoid structures (TLSs) may differ in tumors of lung cancer (LC) patients with/without chronic obstructive pulmonary disease (COPD), and may also influence patient survival. ...
  • Differences in nutritional status and inflammatory biomarkers between female and male patients with bronchiectasis: a large-cohort study
    Wang, Xuejie; Villa, Carmen; Dobarganes, Yadira; Olveira, Casilda; Girón, Rosa; García-Clemente, Marta; Máiz, Luis; Sibila, Oriol; Golpe, Rafael; Menéndez, Rosario; Rodríguez-López, Juan; Prados, Concepción; Martínez-García, Miguel Ángel; Rodriguez, Juan Luis; Rosa, David de la; Duran, Xavier; Barreiro Portela, Esther (MDPI, 2021)
    We hypothesized that systemic inflammatory and nutritional parameters may differ between male and female patients with non-CF bronchiectasis. In a large patient cohort from the Spanish Online Bronchiectasis Registry (RIBRON), ...
  • Do redox balance and inflammatory events take place in mild bronchiectasis? a hint to clinical implications
    Qin, Liyun; Guitart, Maria; Admetlló Papiol, Mireia; Esteban-Cucó, Sandra; Maiques Llácer, José María; Xia, Yingchen; Zha, Jianhua; Carbullanca Toledo, Santiago; Duran, Xavier; Wang, Xuejie; Barreiro Portela, Esther (MDPI, 2021)
    We hypothesized that in mild bronchiectasis patients, increased systemic inflammation and redox imbalance may take place and correlate with clinical parameters. In plasma samples from patients with very mild bronchiectasis, ...
  • Increased PARP activity and DNA damage in NSCLC patients: the influence of COPD
    Tang, Jun; Curull Serrano, Víctor; Wang, Xuejie; Ampurdanés, Coral; Duran, Xavier; Pijuan Andujar, Lara; Rodríguez-Fuster, Alberto; Aguiló Espases, Rafael; Yélamos López, José; Barreiro Portela, Esther (MDPI, 2020)
    Background: Lung cancer (LC) is a major leading cause of death worldwide. Poly (ADP-ribose) polymerase (PARP)-1 and PARP-2 are key players in cancer. We aimed to assess PARP-1 and PARP-2 expression and activity and DNA ...
  • Marcadores de daño miocárdico en la predicción del pronóstico a corto plazo de los pacientes con COVID-19
    Calvo-Fernández, Alicia; Izquierdo Marquisa, Andrea; Subirana Cachinero, Isaac; Farré López, Núria; Vila, Joan; Duran, Xavier; Garcia Guimaraes, Marcos; Valdivielso, Sandra; Cabero, Paula; Soler, Cristina; García-Ribas, Cora; Rodríguez¸ Clara; Llagostera Martín, Marc; Mojón Álvarez, Diana; Vicente Elcano, Miren; Solé-González, Eduard; Sánchez Carpintero, Andrea; Tevar Gómez, Cristina; Marrugat de la Iglesia, Jaume; Vaquerizo Montilla, Beatriz (Elsevier, 2021)
    Introducción y objetivos: La información sobre el daño miocárdico en la población con COVID-19 es muy escasa. Nuestro objetivo fue evaluar el daño cardiaco en pacientes con COVID-19 y determinar la correlación entre las ...
  • Marcadores estromales en el cáncer de pulmón: la influencia de la enfermedad pulmonar obstructiva crònica
    Tang, Jun; Ramis Cabrer, Daniel, 1993-; Curull Serrano, Víctor; Mateu Jiménez, Mercè, 1990-; Almagro, Klara; Duran, Xavier; Pijuan Andujar, Lara; Rodríguez-Fuster, Alberto; Aguiló Espases, Rafael; Barreiro Portela, Esther (Elsevier, 2021)
    Background: Stroma, mainly composed by fibroblasts, extracellular matrix (ECM) and vessels, may play a role in tumorigenesis and cancer progression. Chronic Obstructive Pulmonary Disease (COPD) is an independent risk factor ...
  • Phenotypic clustering in non-cystic fibrosis bronchiectasis patients: the role of eosinophils in disease severity
    Wang, Xuejie; Villa, Carmen; Dobarganes, Yadira; Olveira, Casilda; Girón, Rosa; García-Clemente, Marta; Máiz, Luis; Sibila, Oriol; Golpe, Rafael; Menéndez, Rosario; Rodríguez-López, Juan; Prados, Concepción; Martínez-García, Miguel Ángel; Rodriguez, Juan Luis; Rosa, David de la; Duran, Xavier; García Ojalvo, Jordi; Barreiro Portela, Esther (MDPI, 2021)
    Whether high blood eosinophil counts may define a better phenotype in bronchiectasis patients, as shown in chronic obstructive pulmonary disease (COPD), remains to be investigated. Differential phenotypic characteristics ...
  • Socioeconomic status and prognosis of patients with ST-elevation myocardial infarction managed by the emergency-intervention "Codi IAM" network
    Tizón-Marcos, Helena; Vaquerizo Montilla, Beatriz; Mauri, Josepa; Farré López, Núria; Lidón, Rosa-Maria; Garcia-Picart, Joan; Regueiro, Ander; Ariza, Albert; Carrillo, Xavier; Duran, Xavier; Poirier, Paul; Cladellas Capdevila, M.Mercedes; Camps-Vilaró, Anna; Ribas Barquet, Núria; Cubero Gallego, Héctor; Marrugat de la Iglesia, Jaume (Frontiers, 2022)
    Background: despite the spread of ST-elevation myocardial infarction (STEMI) emergency intervention networks, inequalities in healthcare access still have a negative impact on cardiovascular prognosis. The Family Income ...
  • Sputnik: la guerra fría en órbita
    Duran, Xavier (Universitat Pompeu Fabra, 2007)
  • Systemic profiles of microRNAs, redox balance, and inflammation in lung
    Qin, Liyun; Guitart, Maria; Curull Serrano, Víctor; Sánchez-Font, Albert; Duran, Xavier; Tang, Jun; Admetlló Papiol, Mireia; Barreiro Portela, Esther (MDPI, 2021)
    Lung cancer (LC) risk increases in patients with chronic respiratory diseases (COPD). MicroRNAs and redox imbalance are involved in lung tumorigenesis in COPD patients. Whether systemic alterations of those events may also ...

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