Domedel Puig, Núria; Rué, Pau; Pons, Antonio J.; García Ojalvo, Jordi(Public Library of Science (PLoS), 2011)
Living systems are capable of processing multiple sources of information simultaneously. This is true even at the cellular level, where not only coexisting signals stimulate the cell, but also the presence of fluctuating ...
Rué, Pau; Pons, Antonio J.; Domedel Puig, Núria; García Ojalvo, Jordi(American Institute of Physics (AIP), 2010)
We investigate the dynamics of cell signaling using an experimentally based Boolean model of the human fibroblast signal transduction network. We determine via systematic numerical simulations the relaxation dynamics of ...
Pertsovskaya, Inna; Abad Adan, Elena; Domedel Puig, Núria; García Ojalvo, Jordi; Villoslada, Pablo(BioMed Central, 2013)
Background: Interferon-beta (IFN-beta) activates the immune response through the type I IFN signaling pathway. IFN-beta is important in the response to pathogen infections and is used as a therapy for Multiple Sclerosis. ...
