Browsing by Author "Crespo Barrio, Marta"

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  • A role for human renal tubular epithelial cells in direct allo-recognition by CD4+ T-cells and the effect of ischemia-reperfusion
    Eleftheriadis, Theodoros; Pissas, Georgios; Crespo Barrio, Marta; Nikolaou, Evdokia; Liakopoulos, Vassilios; Stefanidis, Ioannis (MDPI, 2021)
    Direct allorecognition is the earliest and most potent immune response against a kidney allograft. Currently, it is thought that passenger donor professional antigen-presenting cells (APCs) are responsible. Further, many ...
  • Activation of final complement components after kidney transplantation as a marker of delayed graft function severity
    Arias Cabrales, Carlos Enrique; Riera Oliva, Marta; Pérez-Sáez, María José; Gimeno Beltran, Javier; Benito, David; Redondo Pachón, María Dolores; Burballa Tàrrega, Carla, 1988-; Crespo Barrio, Marta; Pascual Santos, Julio; Rodríguez, Eva (Oxford University Press, 2020)
    Background: Ischaemia-reperfusion (I/R) damage is a relevant cause of delayed graft function (DGF). Complement activation is involved in experimental I/R injury, but few data are available from kidney transplant (KT) ...
  • Actualización de las recomendaciones en el manejo de la pandemia por coronavirus SARS-CoV-2 (COVID-19) en pacientes con trasplante renal
    López, Verónica; Crespo Barrio, Marta; Grupo de Estudio GREAT y SENTRA (Elsevier, 2022)
    La infección por el SARS-CoV-2 (COVID-19) ha supuesto un importante impacto en la actividad trasplantadora en nuestro país. Era esperable que la mortalidad y el riesgo de complicaciones asociadas a la COVID-19 en el receptor ...
  • Calcineurin and mTOR inhibitors have opposing effects on regulatory T cells while reducing regulatory B cell populations in kidney transplant recipients.
    Latorre, Irene; Esteve-Solé, Ana; Redondo Pachón, María Dolores; Giest, Sandra; Argilaguet Marqués, Jordi, 1977-; Álvarez, Sara; Peligero Cruz, Cristina, 1986-; Forstmann, Isabelle; Crespo Barrio, Marta; Pascual Santos, Julio; Meyerhans, Andreas (Elsevier, 2016)
    BACKGROUND: Regulatory B (Breg) and T (Treg) cells represent a biomarker for tolerance in transplant patients. Despite the importance of Treg and Breg in transplantation and the suggested crosstalk between both suppressive ...
  • Change in estimated GFR and risk of allograft failure in patients diagnosed with late active antibody-mediated rejection following kidney transplantation
    Irish, William; Nickerson, Peter; Astor, Brad C.; Chong, Edward; Wiebe, Chris; Moreso, Francesc; Seron, Daniel; Crespo Barrio, Marta; Gache, Larry; Djamali, Arjang (Wolters Kluwer (LWW), 2021)
    Background: There are challenges in designing adequate, well-controlled studies of patients with active antibody-mediated rejection (AMR) after kidney transplantation (KTx). Methods: We assessed the functional relationship ...
  • Clinical profiles in renal patients with COVID-19
    Arenas Jiménez, María Dolores; Crespo Barrio, Marta; Pérez-Sáez, María José; Collado Nieto, Silvia; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Barbosa Puig, Francisco; Buxeda, Anna; Burballa Tàrrega, Carla, 1988-; Sans Atxer, Laia; Vázquez, Susana; Oliveras, Anna; Mir, Marisa; Outón González, Sara; Galceran Herrera, Isabel; Solà Porta, Eulàlia; Sierra Ochoa, Adriana; Barrios Barrera, Clara; Rodriguez García, Eva; Cao Baduell, Higinio (MDPI, 2020)
    The COVID-19 pandemic has led to frequent referrals to the emergency department on suspicion of this infection in maintenance hemodialysis (MHD) and kidney transplant (KT) patients. We aimed to describe their clinical ...
  • COVID-19 in elderly kidney transplant recipients
    Crespo Barrio, Marta; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Burballa Tàrrega, Carla, 1988-; Vázquez, Susana; Mir, Marisa; Sierra Ochoa, Adriana; Collado Nieto, Silvia; Barrios Barrera, Clara; Rodriguez García, Eva; Sans Atxer, Laia; Barbosa Puig, Francisco; Cao Baduell, Higinio; Arenas Jiménez, María Dolores; Güerri Fernández, Roberto; Horcajada Gallego, Juan Pablo; Pascual Santos, Julio (Wiley, 2020)
    The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 ...
  • COVID-19 in grade 4-5 chronic kidney disease patients
    Collado Nieto, Silvia; Arenas Jiménez, María Dolores; Barbosa Puig, Francisco; Cao Baduell, Higinio; Montero, Maria Milagro; Villar García, Judit; Barrios Barrera, Clara; Rodriguez García, Eva; Sans Atxer, Laia; Sierra Ochoa, Adriana; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Coca, Armando; Maiques LLacer, José María; Güerri Fernández, Roberto; Horcajada Gallego, Juan Pablo; Crespo Barrio, Marta; Pascual Santos, Julio (Karger (S. Karger AG), 2020)
    Introduction: Chronic kidney disease (CKD) increases the risk of mortality during coronavirus disease 2019 (COVID-19) episodes, and some reports have underlined the high incidence and severity of this infection in dialysis ...
  • COVID-19 in transplant recipients: the Spanish experience
    Coll, Elisabeth; Crespo Barrio, Marta; Domínguez-Gil, Beatriz; Spanish Group for the Study of COVID-19 in Transplant Recipients (Wiley-Blackwell, 2021)
    We report the nationwide experience with solid organ transplant (SOT) and hematopoietic stem cell transplant (HSCT) recipients diagnosed with coronavirus disease 2019 (COVID-19) in Spain until 13 July 2020. We compiled ...
  • Direct-acting antivirals for the treatment of kidney transplant patients with chronic hepatitis C virus infection in Spain: a long-term prospective observational study
    González-Corvillo, Carmen; Crespo Barrio, Marta; Gentil, Miguel Ángel (Wolters Kluwer (LWW), 2019)
    Background: Direct-acting antivirals (DAA) allow effective and safe eradication of hepatitis C virus (HCV) in most patients. There are limited data on the long-term effects of all-oral, interferon-free DAA combination ...
  • Dual Role of Natural Killer Cells on Graft Rejection and Control of Cytomegalovirus Infection in Renal Transplantation
    López-Botet, Miguel; Vilches, Carlos; Redondo Pachón, María Dolores; Muntasell i Castellví, Aura, 1972-; Pupuleku, Aldi, 1985-; Yélamos López, José; Pascual Santos, Julio; Crespo Barrio, Marta (Frontiers, 2017)
    Allograft rejection constitutes a major complication of solid organ transplantation requiring prophylactic/therapeutic immunosuppression, which increases susceptibility of patients to infections and cancer. Beyond the ...
  • Dynamic prediction of renal survival among deeply phenotyped kidney transplant recipients using artificial intelligence: an observational, international, multicohort study
    Raynaud, Marc; Crespo Barrio, Marta; Loupy, Alexandre (Elsevier, 2021)
    Background: kidney allograft failure is a common cause of end-stage renal disease. We aimed to develop a dynamic artificial intelligence approach to enhance risk stratification for kidney transplant recipients by generating ...
  • Early hypertransaminasemia after kidney transplantation: significance and evolution according to donor type
    Solà Porta, Eulàlia; Redondo Pachón, María Dolores; Arias Cabrales, Carlos Enrique; Navazo, Diego; Buxeda, Anna; Burballa Tàrrega, Carla, 1988-; Crespo Barrio, Marta; García-Retortillo, Montserrat; Pascual Santos, Julio; Pérez-Sáez, María José (MDPI, 2021)
    Early hypertransaminasemia after kidney transplantation (KT) is frequent. It has been associated with the crosstalk produced between the liver and the kidney in ischemia-reperfusion situations. However, the influence of ...
  • Endothelial ADAM17 expression in the progression of kidney injury in an obese mouse model of pre-diabetes
    Palau González, Vanesa; Jarrín, Josué; Villanueva, Sofia; Benito, David; Márquez, Eva; Rodríguez, Eva; Soler, María José; Oliveras, Anna; Gimeno, Javier; Sans Atxer, Laia; Crespo Barrio, Marta; Pascual Santos, Julio; Barrios Barrera, Clara; Riera Oliva, Marta (MDPI, 2021)
    Disintegrin and metalloproteinase domain 17 (ADAM17) activates inflammatory and fibrotic processes through the shedding of various molecules such as Tumor Necrosis Factor-α (TNF-α) or Transforming Growht Factor-α (TGF-α). ...
  • Exploring renal changes after bariatric surgery in patients with severe obesity
    Oliveras, Anna; Vázquez, Susana; Soler, María José; Galceran Herrera, Isabel; Duran Jordà, Xavier, 1974-; Goday Arno, Alberto; Benaiges Foix, David; Crespo Barrio, Marta; Pascual Santos, Julio; Riera Oliva, Marta (MDPI, 2022)
    Obesity-related hyperfiltration leads to an increased glomerular filtration rate (GFR) and hyperalbuminuria. These changes are reversible after bariatric surgery (BS). We aimed to explore obesity-related renal changes ...
  • Frailty among chronic kidney disease patients on the kidney transplant waiting list: the sex-frailty paradox
    Pérez-Sáez, María José; Arias Cabrales, Carlos Enrique; Dávalos Yerovi, Vanesa; Redondo Pachón, María Dolores; Faura, Anna; Vera, María; Bach-Pascual, Anna; Pedreira Robles, Guillermo; Junyent-Iglesias, Ernestina; Crespo Barrio, Marta; Marco, Ester; Rodríguez-Mañas, Leocadio; Pascual Santos, Julio; FRAIL-MAR Study Group (Oxford University Press, 2021)
    Background: Frailty is defined as decreased physiologic reserve and resistance to stressors that predisposes patients towards poor health results. Its prevalence in chronic kidney disease (CKD) patients who are kidney ...
  • Gender differences in cancer risk after kidney transplantation
    Buxeda, Anna; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Bartolomé, Álvaro; Mir Fontana, M. Luisa; Pascual-Dapena, Ana; Sans, Anna; Duran Jordà, Xavier, 1974-; Crespo Barrio, Marta; Pascual Santos, Julio (Impact Journals, 2019)
    Kidney transplant (KT) recipients are at greater risk of developing some cancers than the general population. Moreover, cancer is the only cause of death that is currently increasing after kidney transplantation. We analyzed ...
  • High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement
    Montero, Maria Milagro; Mir Fontana, M. Luisa; Sulleiro, Elena; Avalos Esquivel, J.L.; García López, E.; Molina-Morant, D.; López Montesinos, Inmaculada; Sorli Redó, M. Luisa; Veliz Espinosa, G.; Mounteis Oliva, E.; Crespo Barrio, Marta; Monge, I.; Horcajada Gallego, Juan Pablo; Grau Cerrato, Santiago; Pascual Santos, Julio (Elsevier, 2019)
    There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was ...
  • Hypertensive mediated organ damage evolution in resistant hypertension patients after adding spironolactone
    Galceran Herrera, Isabel; Vázquez, Susana; Crespo Barrio, Marta; Pascual Santos, Julio; Oliveras, Anna (Elsevier, 2022)
    Introduction: Resistant hypertension (RH) represents an important multi-organic impact and increases the morbi-mortality. We aimed to evaluate the evolution of hypertensive mediated organ damage in patients with RH after ...
  • Immunoguided discontinuation of prophylaxis for cytomegalovirus disease in kidney transplant recipients treated with antithymocyte globulin: A randomized clinical trial
    Páez-Vega, Aurora; Redondo Pachón, María Dolores; Crespo Barrio, Marta; Torre-Cisneros, Julian (Oxford University Press, 2022)
    Background: Antiviral prophylaxis is recommended in cytomegalovirus (CMV)-seropositive kidney transplant (KT) recipients receiving antithymocyte globulin (ATG) as induction. An alternative strategy of premature discontinuation ...