Browsing by Author "Corvelo, André"

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  • Exon creation and establishment in human genes
    Corvelo, André; Eyras Jiménez, Eduardo (BioMed Central, 2008)
    BACKGROUND: A large proportion of species-specific exons are alternatively spliced. In primates, Alu elements play a crucial role in the process of exon creation but many new exons have appeared through other mechanisms. ...
  • Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx
    Abascal, Federico; Corvelo, André; Cruz, Fernando; Villanueva Cañas, José Luis, 1984-; Vlasova, Anna; Marcet Houben, Marina; Prieto Barja, Pablo, 1986-; Quilez Oliete, Javier; Frias, Leonor; Ribeca, Paolo; Capella Gutiérrez, Salvador Jesús, 1985-; Câmara Ferreira, Francisco; Lowy Gallego, Ernesto; Cozzuto, Luca; Erb, Ionas; Rodríguez Ales, José Luis; Ruiz Orera, Jorge, 1988-; Reverter, Ferran; Derdak, Sophia; Blanc, Julie; Gut, Marta; Lorente-Galdós, Belén, 1981-; Gut, Ivo Glynne; Guigó Serra, Roderic; Gabaldón Estevan, Juan Antonio, 1973-; Godoy, José A. (BioMed Central, 2016)
    Background: Genomic studies of endangered species provide insights into their evolution and demographic history, reveal patterns of genomic erosion that might limit their viability, and offer tools for their effective ...
  • Genome-wide association between branch point properties and alternative splicing
    Corvelo, André; Hallegger, Martina; Smith, Christopher, W. J.; Eyras Jiménez, Eduardo (Public Library of Science (PLoS), 2010)
    The branch point (BP) is one of the three obligatory signals required for pre-mRNA splicing. In mammals, the degeneracy of the motif combined with the lack of a large set of experimentally verified BPs complicates the task ...
  • Massive gene presence-absence variation shapes an open pan-genome in the Mediterranean mussel
    Gerdol, Marco; Cruz, Fernando; Gómez-Garrido, Jèssica; Vlasova, Anna; Naranjo Ortiz, Miguel Ángel, 1989-; Corvelo, André; Frias, Leonor; Gut, Marta; Gabaldón Estevan, Juan Antonio, 1973-; Alioto, Tyler; Figueras, Antonio (BioMed Central, 2020)
    Background: The Mediterranean mussel Mytilus galloprovincialis is an ecologically and economically relevant edible marine bivalve, highly invasive and resilient to biotic and abiotic stressors causing recurrent massive ...
  • Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder
    Teixeira, Cátia M.; Martín, Eduardo D.; Sahún, Ignasi; Masachs, Nuria; Pujadas, Lluís; Corvelo, André; Bosch, Carles; Rossi, Daniela; Martínez, Albert; Maldonado, Rafael, 1961-; Dierssen, Mara; Soriano, Eduardo (Nature Publishing Group, 2011)
    Despite the impact of schizophrenia and mood disorders, which in extreme cases can lead to death, recent decades have brought little progress in the development of new treatments. Recent studies have shown that Reelin, an ...
  • Phylogenomics identifies an ancestral burst of gene duplications predating the diversification of aphidomorpha
    Julca, Irene; Marcet Houben, Marina; Cruz, Fernando; Vargas-Chavez, Carlos; Johnston, John Spencer; Gómez Garrido, Jèssica; Frias, Leonor; Corvelo, André; Loska, Damian; Cámara, Francisco; Gut, Marta; Alioto, Tyler; Latorre, Amparo; Gabaldón Estevan, Juan Antonio, 1973- (Oxford University Press, 2020)
    Aphids (Aphidoidea) are a diverse group of hemipteran insects that feed on plant phloem sap. A common finding in studies of aphid genomes is the presence of a large number of duplicated genes. However, when these duplications ...
  • Whole genome sequencing of turbot (Scophthalmus maximus; Pleuronectiformes): a fish adapted to demersal life
    Figueras, Antonio; Corvelo, André; Gómez Garrido, Jèssica; Gut, Marta; Gut, Ivo Glynne; Marcet Houben, Marina; Vlasova, Anna; Hermoso Pulido, Antonio; Guigó Serra, Roderic; Gabaldón Estevan, Juan Antonio, 1973-; Alioto, Tyler; Martínez, Paulino (Oxford University Press, 2016)
    The turbot is a flatfish (Pleuronectiformes) with increasing commercial value, which has prompted active genomic research aimed at more efficient selection. Here we present the sequence and annotation of the turbot genome, ...