Browsing by Author "Campo, Elias"

Sort by: Order: Results:

  • A practical guide for mutational signature analysis in hematological malignancies
    Maura, Francesco; Degasperi, Andrea; Nadeu, Ferran; Leongamornlert, Daniel; Davies, Helen; Moore, Luiza; Royo, Romina; Ziccheddu, Bachisio; Puente, Xosé S.; Avet-Loiseau, Herve; Campbell, Peter J.; Nik Zainal, Serena; Campo, Elias; Munshi, Nikhil; Bolli, Niccolò (Nature Research, 2019)
    Analysis of mutational signatures is becoming routine in cancer genomics, with implications for pathogenesis, classification, prognosis, and even treatment decisions. However, the field lacks a consensus on analysis and ...
  • Aberrant Epstein-Barr virus antibody patterns and chronic lymphocytic leukemia in a Spanish multicentric case-control study
    Casabonne, Delphine; Benavente, Yolanda; Robles Hellín, Claudia, 1980-; Costas, Laura; Alonso, Esther; González, Eva; Tardón, Adonina; Dierssen Sotos, Trinidad; Gimeno Vázquez, Eva; Aymerich, Marta; Campo, Elias; Castaño Vinyals, Gemma; Aragonés, Núria; Pollan, Marina; Kogevinas, Manolis; Juwana, Hedy; Middeldorp, Jaap; de Sanjosé, Silvia (BioMed Central, 2015)
    Background: Epstein-Barr virus (EBV)-related malignancies harbour distinct serological responses to EBV antigens. We hypothesized that EBV serological patterns can be useful to identify different stages of chronic lymphocytic ...
  • ATM germline variants in a young adult with chronic lymphocytic leukemia: 8 years of genomic evolution
    Royo, Romina; Magnano, Laura; Delgado González, Julio; Ruiz Gil, Sara; Gelpí, Josep Lluís; Heyn, Holger; Taylor, Malcom A.; Stankovic, Tatjana; Puente, Xosé S.; Nadeu, Ferran; Campo, Elias (Nature Research, 2022)
  • Cell-free DNA for genomic analysis in primary mediastinal large B-cell lymphoma
    Rivas-Delgado, Alfredo; Nadeu, Ferran; Andrade-Campos, Marcio; López, Cristina; Enjuanes¸ Anna; Mozas, Pablo; Frigola, Gerard; Colomo Saperas, Luis Alberto; Sánchez González, Blanca; Villamor, Neus; Beà, Sílvia; Campo, Elias; Salar Silvestre, Antonio; Giné, Eva; López Guillermo, Armando; Bellosillo Paricio, Beatriz (MDPI, 2022)
    High-throughput sequencing of cell-free DNA (cfDNA) has emerged as a promising noninvasive approach in lymphomas, being particularly useful when a biopsy specimen is not available for molecular analysis, as it frequently ...
  • Cryptic insertions of the immunoglobulin light chain enhancer region near CCND1 in t(11;14)-negative mantle cell lymphoma
    Fuster-García, Carla; Martín-García, David; Balagué, Olga; Navarro, Alba; Nadeu, Ferran; Costa, Dolors; Prieto, Miriam; Salaverria, Itziar; Espinet Solà, Blanca; Rivas-Delgado, Alfredo; Terol, María-José; Giné, Eva; Forcada, Pilar; Ashton-Key, Margaret; Puente, Xosé S.; Swerdlow, Steven H.; Beà, Sílvia; Campo, Elias (Ferrata Storti Foundation, 2020)
  • Detection of early seeding of Richter transformation in chronic lymphocytic leukemia
    Nadeu, Ferran; Massoni-Badosa, Ramon; Ruiz Gil, Sara; Marchese, Domenica, 1986-; López Bigas, Núria; Gut, Ivo Glynne; Heyn, Holger; Campo, Elias (Nature Research, 2022)
    Richter transformation (RT) is a paradigmatic evolution of chronic lymphocytic leukemia (CLL) into a very aggressive large B cell lymphoma conferring a dismal prognosis. The mechanisms driving RT remain largely unknown. ...
  • Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation
    Vilarrasa-Blasi, Roser; Soler-Vila, Paula; Verdaguer-Dot, Núria; Russiñol, Núria; Di Stefano, Marco; Chapaprieta, Vicente; Clot, Guillem; Farabella, Irene; Cuscó Pons, Pol, 1987-; Kulis, Marta; Agirre, Xabier; Prosper, Felipe; Beekman, Renée; Beà, Sílvia; Colomer Pujol, Dolors; Stunnenberg, Hendrik G.; Gut, Ivo Glynne; Campo, Elias; Marti-Renom, Marc A.; Martin-Subero, José Ignacio (Nature Research, 2021)
    To investigate the three-dimensional (3D) genome architecture across normal B cell differentiation and in neoplastic cells from different subtypes of chronic lymphocytic leukemia and mantle cell lymphoma patients, here we ...
  • IG/MYC rearrangements are the main cytogenetic alteration in plasmablastic lymphomas
    Valera, Alexandra; Balagué, Olga; Colomo Saperas, Luis Alberto; Martínez García, Antonio; Delabie, Jan; Taddesse-Heath, Lekidelu; Jaffe, Elaine S.; Campo, Elias (Lippincott Williams & Wilkins, 2010)
    Plasmablastic lymphoma (PBL) is an aggressive lymphoma characterized by a terminally differentiated B-cell phenotype that usually occurs in the immunocompromised or elderly patients. Although the clinical and pathologic ...
  • Insulin-like growth factor levels and chronic lymphocytic leukaemia: results from the MCC-Spain and EpiLymph-Spain studies
    Casabonne, Delphine; Benavente, Yolanda; Costas, Laura; Robles Hellín, Claudia, 1980-; González, Eva; de la Banda, Esmeralda; Alonso, Esther; Aymerich, Marta; Campo, Elias; Marcos-Gragera, Rafael; Tardón, Adonina; Olmedo-Requena, Rocío; Gimeno Vázquez, Eva; Martınez-Lopez, Alba; Casanovas, Oriol; Castaño Vinyals, Gemma; Aragonés, Núria; Pollan, Marina; Kogevinas, Manolis; de Sanjosé, Silvia (Wiley-Blackwell, 2019)
  • Lifetime exposure to brominated trihalomethanes in drinking water and swimming pool attendance are associated with chronic lymphocytic leukemia: a Multicase-Control Study in Spain (MCC-Spain)
    Donat-Vargas, Carolina; Kogevinas, Manolis; Benavente, Yolanda; Costas, Laura; Campo, Elias; Castaño Vinyals, Gemma; Fernandez-Tardon, Guillermo; Llorca, Javier; Gómez-Acebo, Inés; Aragonés, Núria; Pollan, Marina; Casabonne, Delphine; Villanueva Belmonte, Cristina (Nature Research, 2023)
    Background: Chronic lymphocytic leukemia (CLL) etiology is poorly understood, and carcinogenic chemicals in drinking and recreational water are candidates. Objective: To evaluate the association between drinking-water ...
  • Mutational profile and pathological features of a case of interleukin-10 and RGS1-positive spindle cCell variant diffuse large B-Cell lymphoma
    Carreras, Joaquim; Kikuti, Yara Yukie; Miyaoka, Masashi; Hiraiwa, Shinichiro; Tomita, Sakura; Ikoma, Haruka; Kondo, Yusuke; Ito, Atsushi; Nagase, Shunsuke; Miura, Hisanobu; Roncador, Giovanna; Colomo Saperas, Luis Alberto; Hamoudi, Rifat; Campo, Elias; Nakamura, Naoya (MDPI, 2023)
    Diffuse large B-cell lymphoma with spindle cell morphology is a rare variant. We present the case of a 74-year-old male who initially presented with a right supraclavicular (lymph) node enlargement. Histological analysis ...
  • Nonhepatosplenic γδ T-cell lymphomas represent a spectrum of aggressive cytotoxic T-cell lymphomas with a mainly extranodal presentation
    Garcia-Herrera, Adriana; Song, Joo Y.; Chuang, Shih-Sung; Villamor, Neus; Colomo Saperas, Luis Alberto; Pittaluga, Stefania; Alvaro, Tomas; Rozman, Maria; Anda Gonzalez, Jazmin de; Arrunategui, Ana Maria; Fernandez, Eva; Gonzalvo, Elena; Estrach, Teresa; Colomer Pujol, Dolors; Raffeld, Mark; Gaulard, Philippe; Campo, Elias; Jaffe, Elaine S.; Martinez, Antonio (Lippincott Williams & Wilkins, 2011)
    γδ T cells represent a minor T-cell subset that is mainly distributed in mucosal surfaces. Two distinct lymphomas derived from these cells have been recognized: hepatosplenic γδ T-cell lymphoma (HSTL) and primary cutaneous ...
  • Sampling time-dependent artifacts in single-cell genomics studies
    Massoni-Badosa, Ramon; Iacono, Giovanni; Moutinho, Catia; Kulis, Marta; Palau, Núria; Marchese, Domenica, 1986-; Rodríguez Ubreva, Javier; Ballestar, Esteban; Rodríguez Esteban, Gustavo; Marsal, Sara; Aymerich, Marta; Colomer Pujol, Dolors; Campo, Elias; Julià Cano, Antoni; Martín-Subero, José Ignacio; Heyn, Holger (BioMed Central, 2020)
    Robust protocols and automation now enable large-scale single-cell RNA and ATAC sequencing experiments and their application on biobank and clinical cohorts. However, technical biases introduced during sample acquisition ...
  • Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia
    Gimenez, Neus; Tripathi, Rupal; Giró, Ariadna; Rosich, Laia; López-Guerra, Mónica; López-Oreja, Irene; Playa-Albinyana, Heribert; Arenas, Fabián; Mas, José Manuel; Pérez-Galán, Patricia; Delgado González, Julio; Campo, Elias; Farrés, Judith; Colomer Pujol, Dolors (Nature Research, 2020)
    Chronic lymphocytic leukemia (CLL) is a B lymphoid malignancy highly dependent on the microenvironment. Despite new targeted therapies such as ibrutinib and venetoclax, disease progression and relapse remain an issue. CLL ...
  • The receptor of the colony-stimulating factor-1 (CSF-1R) is a novel prognostic factor and therapeutic target in follicular lymphoma
    Garcia Valero, Juan; Matas-Céspedes, Alba; Arenas, Fabián; Rodriguez, Vanina; Carreras, Joaquim; Serrat, Neus; Guerrero-Hernández, Martina; Yahiaoui, Anella; Balagué, Olga; Martin, Silvia; Capdevila, Cristina; Hernández, Lluis; Magnano, Laura; Rivas-Delgado, Alfredo; Tannheimer, Stacey; Cid, Maria C.; Campo, Elias; López Guillermo, Armando; Colomer Pujol, Dolors; Pérez-Galán, Patricia (Springer Nature, 2021)
    Microenvironment contributes to follicular lymphoma (FL) pathogenesis and impacts survival with macrophages playing a controversial role. In the present study, using FL primary samples and HK follicular dendritic cells ...
  • Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
    Puente, Xosé S.; Escaramís, Geòrgia; Bassaganyas Bars, Laia, 1985-; Tubio, José M. C.; Tornador Antolin, Cristian, 1979-; Himmelbauer, Heinz; Castillo Andreo, Esther; Dohm, Juliane C.; Guigó Serra, Roderic; Estivill, Xavier, 1955-; Campo, Elias (Nature Research, 2011)
    Chronic lymphocytic leukaemia (CLL), the most frequent leukaemia in adults in Western countries, is a heterogeneous disease with variable clinical presentation and evolution. Two major molecular subtypes can be distinguished, ...

Search DSpace

Browse

My Account

In collaboration with Compliant to Partaking