Browsing by Author "Brun-Heath, Isabelle"

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  • Keraite, Ieva; Becker, Philipp; Canevazzi, Davide; Frias-López, Cristina; Dabad, Marc; Tonda, Raúl; Paramonov, Ida; Ingham, Matthew; Brun-Heath, Isabelle; Leno, Jordi; Abulí, Anna; García-Arumí, Elena; Heath, Simon; Gut, Marta; Gut, Ivo Glynne (Nature Research, 2022)
    Methods to reconstruct the mitochondrial DNA (mtDNA) sequence using short-read sequencing come with an inherent bias due to amplification and mapping. They can fail to determine the phase of variants, to capture multiple ...
  • Bertoni, Martino; Duran-Frigola, Miquel, 1985-; Badia-I-Mompel, Pau; Pauls, Eduardo; Orozco Ruiz, Modesto; Guitart Pla, Oriol; Alcalde, Víctor; Diaz, Víctor M.; Berenguer-Llergo, Antonio; Brun-Heath, Isabelle; Villegas, Núria; García de Herreros, Antonio; Aloy, Patrick, 1972- (Nature Research, 2021)
    Chemical descriptors encode the physicochemical and structural properties of small molecules, and they are at the core of chemoinformatics. The broad release of bioactivity data has prompted enriched representations of ...
  • Buitrago, Diana; Labrador, Mireia; Arcon, Juan Pablo; Lema, Rafael; Flores, Oscar; Esteve-Codina, Anna; Blanc, Julie; Villegas, Núria; Bellido, David; Gut, Marta; Dans, Pablo D.; Heath, Simon; Gut, Ivo Glynne; Brun-Heath, Isabelle; Orozco, Modesto (Nature Research, 2021)
    Determining the effect of DNA methylation on chromatin structure and function in higher organisms is challenging due to the extreme complexity of epigenetic regulation. We studied a simpler model system, budding yeast, ...
  • Buitrago, Diana; Codó, Laia; Illa, Ricard; Jorge, Pau de; Battistini, Federica; Flores, Oscar; Bayarri, Genis; Royo, Romina; Pino, Marc del; Heath, Simon; Hospital, Adam; Gelpí, Josep Lluís; Brun-Heath, Isabelle; Orozco, Modesto (Oxford University Press, 2019)
    We present Nucleosome Dynamics, a suite of programs integrated into a virtual research environment and created to define nucleosome architecture and dynamics from noisy experimental data. The package allows both the ...
  • De Mol, Eva; Szulc, Elzbieta; Di Sanza, Claudio; Martínez-Cristóbal, Paula; Bertoncini, Carlos W.; Fenwick, R. Bryn; Frigolé-Vivas, Marta; Masín, Marianela; Hunter, Irene; Buzón, Víctor; Brun-Heath, Isabelle; García, Jesús; De Fabritiis, Gianni; Estébanez-Perpiñá, Eva; McEwan, Iain J.; Nebreda, Ángel R.; Salvatella, Xavier (Elsevier, 2018)
    The androgen receptor is a transcription factor that plays a key role in the development of prostate cancer, and its interactions with general transcription regulators are therefore of potential therapeutic interest. The ...

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