Browsing by Author "Böttcher, René"

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  • Viéitez Manrique, Cristina, 1984-; Martínez Cebrián, Gerard, 1992-; Solé, Carme; Böttcher, René; Potel, Clement M.; Savitski, Mikhail M.; Onnebo, Sara; Fabregat, Marc; Shilatifard, Ali; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (Oxford University Press, 2020)
    Cells have the ability to sense, respond and adapt to environmental fluctuations. Stress causes a massive reorganization of the transcriptional program. Many examples of histone post-translational modifications (PTMs) have ...
  • Carbonell Núñez, Caterina, 1987-; Ulsamer, Arnau; Vivori, Claudia, 1989-; Papasaikas, Panagiotis; Böttcher, René; Joaquin i Caudet, Manel; Miñana Gómez, Belén; Tejedor Vaquero, Juan Ramón, 1984-; Nadal Clanchet, Eulàlia de; Valcárcel, J. (Juan); Posas Garriga, Francesc (Elsevier, 2019)
    Alternative splicing is a prevalent mechanism of gene regulation that is modulated in response to a wide range of extracellular stimuli. Stress-activated protein kinases (SAPKs) play a key role in controlling several steps ...
  • Chen, Tzu-Chun; Talló Parra, Marc, 1992-; Cao, Qian M.; Kadener, Sebastian; Böttcher, René; Pérez Vilaró, Gemma, 1985-; Boonchuen, Pakpoom; Somboonwiwat, Kunlaya; Díez Antón, Juana, 1962-; Sarnow, Peter (Public Library of Science (PLoS), 2020)
    Viruses subvert macromolecular pathways in infected host cells to aid in viral gene amplification or to counteract innate immune responses. Roles for host-encoded, noncoding RNAs, including microRNAs, have been found to ...
  • Serra, Selma A.; Stojakovic, Predrag; Amat, Ramon; Rubio Moscardó, Fanny; Latorre Doménech, Pablo, 1993-; Seisenbacher, Gerhard; Canadell, David; Böttcher, René; Aregger, Michael; Moffat, Jason; Nadal Clanchet, Eulàlia de; Valverde, M. A. (Miguel Ángel), 1963-; Posas Garriga, Francesc (National Academy of Sciences, 2021)
    Regulation of cell volume is essential for tissue homeostasis and cell viability. In response to hypertonic stress, cells need rapid electrolyte influx to compensate water loss and to prevent cell death in a process known ...
  • Amat, Ramon; Böttcher, René; Le Dily, François; Vidal Ocabo, Enrique; Quilez Oliete, Javier; Cuartero, Yasmina; Beato, Miguel; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Cold Spring Harbor Laboratory Press (CSHL Press), 2019)
    Nuclear architecture is decisive for the assembly of transcriptional responses. However, how chromosome organization is dynamically modulated to permit rapid and transient transcriptional changes in response to environmental ...
  • Silva, Andrea; Cavero, Santiago; Begley, Victoria; Solé, Carme; Böttcher, René; Chávez, Sebastián; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (Public Library of Science (PLoS), 2017)
    Cells trigger massive changes in gene expression upon environmental fluctuations. The Hog1 stress-activated protein kinase (SAPK) is an important regulator of the transcriptional activation program that maximizes cell ...
  • Blasco-Moreno, Bernat; de Campos-Mata, Leire; Böttcher, René; García-Martínez, José; Jungfleisch, Jennifer, 1986-; Nedialkova, Danny D.; Chattopadhyay, Shiladitya; Gas, María-Eugenia; Oliva Miguel, Baldomero; Pérez Ortín, José E.; Leidel, Sebastian; Choder, Mordechai; Díez Antón, Juana, 1962- (Nature Research, 2019)
    The highly conserved 5’–3’ exonuclease Xrn1 regulates gene expression in eukaryotes by coupling nuclear DNA transcription to cytosolic mRNA decay. By integrating transcriptome-wide analyses of translation with biochemical ...