Browsing by Author "Arató, Krisztina, 1981-"

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  • A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response
    Roewenstrunk, Julia Maria, 1981-; Di Vona, Chiara, 1981-; Chen, Jie; Borràs, Eva; Dong, Chao; Arató, Krisztina, 1981-; Sabidó Aguadé, Eduard, 1981-; Huen, Michael S. Y.; Luna Gargantilla, Susana de la (Nature Research, 2019)
    Dysregulation of the DYRK1A protein kinase has been associated with human disease. On the one hand, its overexpression in trisomy 21 has been linked to certain pathological traits of Down syndrome, while on the other, ...
  • A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival
    Lara-Chica, Maribel; Correa-Sáez, Alejandro; Jiménez-Izquierdo, Rafael; Garrido-Rodríguez, Martín; Ponce, Francisco J.; Moreno, Rita; Morrison, Kimberley; Di Vona, Chiara, 1981-; Arató, Krisztina, 1981-; Jiménez-Jiménez, Carla; Morrugares, Rosario; Schmitz, M. Lienhard; Luna, Susana de la; Vega, Laureano de la; Calzado, Marco A. (Nature Research, 2022)
    The cell division cycle 25A (CDC25A) phosphatase is a key regulator of cell cycle progression that acts on the phosphorylation status of Cyclin-Cyclin-dependent kinase complexes, with an emergent role in the DNA damage ...
  • DYRK1A-mediated phosphorylation of GluN2A at Ser1048 regulates the surface expression and channel activity of GluN1/GluN2A receptors
    Grau, Cristina; Arató, Krisztina, 1981-; Fernández-Fernández, José Manuel, 1967-; Valderrama, Aitana; Sindreu, Carlos; Fillat i Fonts, Cristina; Ferrer, Isidre; Luna, Susana de la; Altafaj, Xavier (Frontiers, 2014)
    N-methyl-D-aspartate glutamate receptors (NMDARs) play a pivotal role in neural development and synaptic plasticity, as well as in neurological disease. Since NMDARs exert their function at the cell surface, their density ...
  • Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome
    Arranz, Juan; Balducci, Elisa, 1981-; Arató, Krisztina, 1981-; Sánchez-Elexpuru, Gentzane; Najas Sales, Sònia, 1985-; Parras, Alberto; Rebollo, Elena; Pijuan, Isabel; Erb, Ionas; Verde, Gaetano; Sahún, Ignasi; Barallobre, María José; Lucas, José J.; Sánchez, Marina P.; de la Luna, Susana; Arbonés de Rafael, Maria Lourdes, 1959- (Elsevier, 2019)
    Autism spectrum disorders are early onset neurodevelopmental disorders characterized by deficits in social communication and restricted repetitive behaviors, yet they are quite heterogeneous in terms of their genetic basis ...
  • Key Role of Amino Acid Repeat Expansions in the Functional Diversification of Duplicated Transcription Factors.
    Radó i Trilla, Núria, 1985-; Arató, Krisztina, 1981-; Pegueroles Queralt, Maria Cinta; Raya, Alicia; Luna, Susana de la; Albà Soler, Mar (Open University Press, 2015)
    The high regulatory complexity of vertebrates has been related to two rounds of whole genome duplication (2R-WGD) that occurred before the divergence of the major vertebrate groups. Following these events, many developmental ...

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