Browsing by Author "Angona Figueras, Anna"

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  • Characterization of CD34+ hematopoietic progenitor cells in JAK2V617F and CALR-mutated myeloproliferative neoplasms.
    Angona Figueras, Anna; Álvarez Larrán, Alberto; Bellosillo Paricio, Beatriz; Longarón Rozalen, Raquel; Camacho Díaz, Laura; Fernández Rodríguez, M. Concepción; Pairet García, Silvia; Besses Raebel, Carles (Elsevier, 2016)
    Mutations in JAK2 or CALR are observed in patients with myeloproliferative neoplasms (MPN). To get further insight in the dynamics of the mutant clone, we assessed the mutant allele burden in hematopoietic stem cells (HSCs), ...
  • Feasibility of treatment discontinuation in chronic myeloid leukemia in clinical practice: results from a nationwide series of 236 patients
    Hernández-Boluda, Juan Carlos; Angona Figueras, Anna; Steegmann, Juan Luis; Grupo Español de Leucemia Mieloide Crónica (GELMC) (Nature Publishing Group, 2018)
    Over half of chronic myeloid leukemia (CML) patients in deep molecular response do not lose the major molecular response (MMR) after stopping treatment with tyrosine kinase inhibitors (TKI). This strategy is safe in clinical ...
  • Impact of genotype on leukaemic transformation in polycythaemia vera and essential thrombocythaemia
    Alvarez-Larrán, Alberto; Senín Magan, Maria Alicia; Fernández Rodríguez, M. Concepción; Pereira, Arturo; Arellano-Rodrigo, Arturo; Gómez, Montse; Ferrer-Marín, Francisca; Martínez-López, Joaquín; Camacho Díaz, Laura; Colomer Pujol, Dolors; Angona Figueras, Anna; Navarro, Blanca; Cervantes, Francisco; Besses Raebel, Carles; Bellosillo Paricio, Beatriz; Hernández-Boluda, Juan Carlos (Wiley, 2017)
    The influence of driver mutations on leukaemic transformation was analysed in 1747 patients with polycythaemia vera or essential thrombocythaemia. With a median follow-up of 7·2 years, 349 patients died and 62 progressed ...
  • Impact of individual comorbidities on survival of patients with myelofibrosis
    García-Fortes, María; Hernández-Boluda, Juan Carlos; Alvarez-Larrán, Alberto; Raya, José M.; Angona Figueras, Anna; Estrada, Natalia; Fox, Laura; Cuevas, Beatriz; García-Hernández, María C.; Gómez-Casares, Maria-Teresa; Ferrer-Marín, Francisca; Saavedra, Silvana; Cervantes, Francisco; García-Delgado, Regina; Grupo Español de Enfermedades Mieloproliferativas Filadelfia Negativas Gemfin (MDPI, 2022)
    The comorbidity burden is an important risk factor for overall survival (OS) in several hematological malignancies. This observational prospective study was conducted to evaluate the impact of individual comorbidities on ...
  • Masked polycythaemia vera: presenting features, response to treatment and clinical outcomes.
    Álvarez Larrán, Alberto; Angona Figueras, Anna; Ancochea Serra, Agueda; García-Pallarols, Francesc; Fernández Rodríguez, M. Concepción; Longarón Rozalen, Raquel; Bellosillo Paricio, Beatriz; Besses Raebel, Carles (Wiley, 2016)
    Masked polycythaemia vera (PV) has been proposed as a new entity with poorer outcome than overt PV. In this study, the initial clinical and laboratory characteristics, response to treatment and outcome of masked and overt ...
  • Molecular characterisation of triple negative essential thrombocythaemia patients by platelet analysis and targeted sequencing.
    Angona Figueras, Anna; Fernández Rodríguez, M. Concepción; Álvarez Larrán, Alberto; Camacho Díaz, Laura; Longarón Rozalen, Raquel; Torres, Erica; Pairet García, Silvia; Besses Raebel, Carles; Bellosillo Paricio, Beatriz (Nature Publishing Group, 2016)
    Essential thrombocythaemia (ET) is a myeloproliferative neoplasm(MPN) characterised by megakaryocyte hyperplasia and thrombo-cytosis. From the genetic perspective, ET patients harbourmutations inJAK2(50–60%),CALR(15–30%) ...