Browsing by Author "Aldecoa, Iban"

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  • Atypical astroglial pTDP-43 pathology in astroglial predominant tauopathy
    Gelpi, Ellen; Aldecoa, Iban; López Villegas, Dolores; Abellan-Vidal, María Teresa; Mercadel Fañanas, Pilar; Fortea, Juan; Ribosa, Roser; Morenas-Rodriguez, Estrella; Gómez Anson, Beatriz; Molina Porcel, Laura; Ximelis, Teresa; Borrego-Ecija, Sergi; Antonell Boixader, Anna; Rovelet Lecrux, Anne; Klotz, Sigrid; Andrés Benito, Pol; Sánchez Valle, Raquel; Ferrer, Isidre (Wiley, 2021)
    We observed atypical astrocytic pTDP-43 pathology in astroglial predominant tauopathy.
  • In silico validation of RNA-Seq results can identify gene fusions with oncogenic potential in glioblastoma
    Hernandez, Ainhoa; Muñoz-Mármol, Ana M.; Esteve-Codina, Anna; Alameda Quitllet, Francisco; Carrato, Cristina; Pineda, Estela; Arpí Llucià, Oriol; Martinez-García, Maria; Mallo, Mar; Gut, Marta; Barco Berrón, Sonia del; Gallego, Oscar; Dabad, Marc; Mesia, Carlos; Bellosillo Paricio, Beatriz; Domenech, Marta; Vidal, Noemí; Aldecoa, Iban; Iglesia, Nuria de la; Balana, Carmen (Nature Research, 2022)
    RNA-Sequencing (RNA-Seq) can identify gene fusions in tumors, but not all these fusions have functional consequences. Using multiple data bases, we have performed an in silico analysis of fusions detected by RNA-Seq in ...
  • Preclinical studies with glioblastoma brain organoid co-cultures show efficient 5-ALA photodynamic therapy
    Pedrosa, Leire; Bedia, Carmen; Diao, Diouldé; Mosteiro, Alejandra; Ferrés, Abel; Stanzani, Elisabetta; Martínez-Soler, Fina; Tortosa, Avelina; Pineda, Estela; Aldecoa, Iban; Centellas, Marc; Muñoz-Tudurí, Marta; Sevilla, Ana; Sierra, Àngels; González Sánchez, José Juan (MDPI, 2023)
    Background: The high recurrence of glioblastoma (GB) that occurs adjacent to the resection cavity within two years of diagnosis urges an improvement of therapies oriented to GB local control. Photodynamic therapy (PDT) has ...
  • Texture analysis of the apparent diffusion coefficient focused on contrast-enhancing Lesions in predicting survival for Bevacizumab-Treated patients with recurrent glioblastoma
    López-Rueda, Antonio; Puig, Josep; Thió-Henestrosa, Santiago; Moreno-Negrete, Javier Luis; Zwanzger, Christian; Pujol, Teresa; Aldecoa, Iban; Pineda, Estela; Valduvieco, Izaskun; González, José Juan; Oleaga, Laura (MDPI, 2023)
    Purpose: Glioblastoma often recurs after treatment. Bevacizumab increases progression-free survival in some patients with recurrent glioblastoma. Identifying pretreatment predictors of survival can help clinical decision ...
  • The C250T mutation of TERTp might grant a better prognosis to glioblastoma by exerting less biological effect on telomeres and chromosomes than the C228T mutation
    Gorria, Teresa; Crous-Bou, Marta; Pineda, Estela; Hernandez, Ainhoa; Domenech, Marta; Sanz, Carolina; Jares, Pedro; Muñoz Mármol, Ana María; Arpí Llucià, Oriol; Meléndez, Bárbara; Gut, Marta; Esteve, Anna; Esteve-Codina, Anna; Parra Farré, Genís; Alameda Quitllet, Francisco; Carrato, Cristina; Aldecoa, Iban; Mallo, Mar; Iglesia, Nuria de la; Balana, Carmen (MDPI, 2024)
    The aim of this study was to determine how TERTp mutations impact glioblastoma prognosis. Materials and methods: TERTp mutations were assessed in a retrospective cohort of 258 uniformly treated glioblastoma patients. ...

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