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Browsing by Author "Álvarez Larrán, Alberto"
Now showing items 1-9 of 9
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Álvarez Larrán, Alberto; Besses Raebel, Carles (Ferrata Storti Foundation, 2016)The role of antiplatelet therapy as primary prophylaxis of thrombosis in low-risk essential thrombocythemia has not been studied in randomized clinical trials. We assessed the benefit/risk of low-dose aspirin in 433 patients ...
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Angona Figueras, Anna; Álvarez Larrán, Alberto; Bellosillo Paricio, Beatriz; Longarón Rozalen, Raquel; Camacho Díaz, Laura; Fernández Rodríguez, M. Concepción; Pairet García, Silvia; Besses Raebel, Carles (Elsevier, 2016)Mutations in JAK2 or CALR are observed in patients with myeloproliferative neoplasms (MPN). To get further insight in the dynamics of the mutant clone, we assessed the mutant allele burden in hematopoietic stem cells (HSCs), ...
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Besses Raebel, Carles; Álvarez Larrán, Alberto (Elsevier, 2016)Polycythemia vera and essential thrombocythemia (ET) are chronic myeloproliferative neoplasms associated with thrombotic or hemorrhagic complications, and increased risk of transformation to myelofibrosis and acute myeloid ...
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Álvarez Larrán, Alberto; Angona Figueras, Anna; Ancochea Serra, Agueda; García-Pallarols, Francesc; Fernández Rodríguez, M. Concepción; Longarón Rozalen, Raquel; Bellosillo Paricio, Beatriz; Besses Raebel, Carles (Wiley, 2016)Masked polycythaemia vera (PV) has been proposed as a new entity with poorer outcome than overt PV. In this study, the initial clinical and laboratory characteristics, response to treatment and outcome of masked and overt ...
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Navarro, A.; Pairet García, Silvia; Álvarez Larrán, Alberto; Pons, A.; Ferrer, G.; Longarón Rozalen, Raquel; Fernández Rodríguez, M. Concepción; Camacho Díaz, Laura; Monzó, M.; Besses Raebel, Carles; Bellosillo Paricio, Beatriz (Nature Publishing Group, 2016)The biological basis of essential thrombocythemia (ET) patients lacking known mutations is still unknown. MicroRNAs (miRNA) regulate hematopoietic differentiation and are deregulated in several hematopoietic malignancies. ...
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Angona Figueras, Anna; Fernández Rodríguez, M. Concepción; Álvarez Larrán, Alberto; Camacho Díaz, Laura; Longarón Rozalen, Raquel; Torres, Erica; Pairet García, Silvia; Besses Raebel, Carles; Bellosillo Paricio, Beatriz (Nature Publishing Group, 2016)Essential thrombocythaemia (ET) is a myeloproliferative neoplasm(MPN) characterised by megakaryocyte hyperplasia and thrombo-cytosis. From the genetic perspective, ET patients harbourmutations inJAK2(50–60%),CALR(15–30%) ...
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Álvarez Larrán, Alberto; Cruz, Yasmina; Montesdeoca Romero, Sara; García-Pallarols, Francesc; Besses Raebel, Carles; Grupo Español de Neoplasias Mieloproliferativas Filadelfia Negativas (Ferrata Storti Foundation, 2017)Hematocrit control below 45% is associated with a lower rate of thrombosis in polycythemia vera. In patients receiving hydroxyurea, this target can be achieved with hydroxyurea alone or with the combination of hydroxyurea ...
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de Freitas, Ana Sofia; Álvarez Larrán, Alberto (Springer, 2016)Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by an expansion of red cell mass which leads to an increased risk of thrombotic and hemorrhagic complications.
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de Stefano, Valerio; Álvarez Larrán, Alberto; Barbui, Tiziano (Nature Publishing Group, 2016)We retrospectively studied 181 patients with polycythaemia vera (n=67), essential thrombocythaemia (n=67) or primary myelofibrosis (n=47), who presented a first episode of splanchnic vein thrombosis (SVT). Budd-Chiari ...
Now showing items 1-9 of 9
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