Zoonomia ConsortiumSerres Armero, Aitor, 1992-Juan, DavidKuderna, Lukas, 1989-Marquès i Bonet, Tomàs, 1975-2020-12-182020-12-182020Zoonomia Consortium, Serres A, Juan D, Kuderna D. L. F. K., Marques-Bonet T. A comparative genomics multitool for scientific discovery and conservation. Nature. 2020 Nov; 587(7833): 240-5. DOI: 10.1038/s41586-020-2876-60028-0836http://hdl.handle.net/10230/46082The Zoonomia Project is investigating the genomics of shared and specialized traits in eutherian mammals. Here we provide genome assemblies for 131 species, of which all but 9 are previously uncharacterized, and describe a whole-genome alignment of 240 species of considerable phylogenetic diversity, comprising representatives from more than 80% of mammalian families. We find that regions of reduced genetic diversity are more abundant in species at a high risk of extinction, discern signals of evolutionary selection at high resolution and provide insights from individual reference genomes. By prioritizing phylogenetic diversity and making data available quickly and without restriction, the Zoonomia Project aims to support biological discovery, medical research and the conservation of biodiversity.application/pdfeng© Aitor Serres et al. 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were madeGenòmicaMamífersDescobriments científicsMedicina -- InvestigacióBiodiversitat -- ConservacióA comparative genomics multitool for scientific discovery and conservationinfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1038/s41586-020-2876-6info:eu-repo/semantics/openAccess