Terré, BertaPiergiovanni, GabrieleSegura-Bayona, SandraGil Gómez, GabrielYoussef, Sameh A.Attolini, Camille Stephan-OttoWilsch-Bräuninger, MichaelaJung, CaroleRojas Mendoza, Ana MariaMarjanovi c, MarkoKnobel, Philip A.Palenzuela, LluísLópez-Rovira, TeresaForrow, StephenHuttner, Wieland B.Valverde, M. A. (Miguel Ángel), 1963-de Bruin, AlainCostanzo, VincenzoStracker, Travis2016-05-192016Terré B1, Piergiovanni G, Segura-Bayona S, Gil-Gómez G, Youssef SA, Attolini CS. et al. GEMC1 is a critical regulator of multiciliated cell differentiation. EMBO J. 2016 May 2;35(9):942-60. DOI: 10.15252/embj.201592821.0261-4189http://hdl.handle.net/10230/26303The generation of multiciliated cells (MCCs) is required for the proper function of many tissues, including the respiratory tract, brain, and germline. Defects in MCC development have been demonstrated to cause a subclass of mucociliary clearance disorders termed reduced generation of multiple motile cilia (RGMC). To date, only two genes, Multicilin (MCIDAS) and cyclin O (CCNO) have been identified in this disorder in humans.application/pdfeng© Wiley-Blackwell. The definitive version is available online at: http://dx.doi.org/10.15252/embj.201592821HidrocefàliaEsterilitatinfo:eu-repo/semantics/articlehttp://dx.doi.org/10.15252/embj.201592821info:eu-repo/semantics/openAccess