Crespo Barrio, MartaPérez-Sáez, María JoséRedondo Pachón, María DoloresLlinàs-Mallol, LauraMontero, Maria MilagroVillar García, JuditArias Cabrales, Carlos EnriqueBurballa Tàrrega, Carla, 1988-Vázquez, SusanaMir, MarisaSierra Ochoa, AdrianaCollado Nieto, SilviaBarrios Barrera, ClaraRodriguez García, EvaSans Atxer, LaiaBarbosa Puig, FranciscoCao Baduell, HiginioArenas Jiménez, María DoloresGüerri Fernández, RobertoHorcajada Gallego, Juan PabloPascual Santos, Julio2020-11-192020-11-192020Crespo M, Pérez-Sáez MJ, Redondo-Pachón D, Llinàs-Mallol L, Montero MM, Villar-García J. et al. COVID-19 in elderly kidney transplant recipients. Am J Transplant. 2020 Oct; 20(10): 2883-89. DOI: 10.1111/ajt.160961600-6135http://hdl.handle.net/10230/45810The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 KT patients aged ≥65 years old (4.9%). Many of them had had contact with healthcare facilities in the month prior to infection. Median time of symptom onset to admission was 7 days. All presented with fever and all but one with pneumonia. Up to 33% showed renal graft dysfunction. At infection diagnosis, mTOR inhibitors or mycophenolate were withdrawn. Tacrolimus was withdrawn in 70%. The main treatment combination was hydroxychloroquine and azithromycin. A subset of patients was treated with anti-retroviral and tocilizumab. Short-term fatality rate was 50% at a median time since admission of 3 days. Those who died were more frequently obese, frail, and had underlying heart disease. Although a higher respiratory rate was observed at admission in nonsurvivors, symptoms at presentation were similar between both groups. Patients who died were more anemic, lymphopenic, and showed higher D-dimer, C-reactive protein, and IL-6 at their first tests. COVID-19 is frequent among the elderly KT population and associates a very early and high mortality rate.application/pdfengThis is the peer reviewed version of the following article: Crespo M, Pérez-Sáez MJ, Redondo-Pachón D, Llinàs-Mallol L, Montero MM, Villar-García J. et al. COVID-19 in elderly kidney transplant recipients. Am J Transplant. 2020 Oct; 20(10): 2883-89, which has been published in final form at http://dx.doi.org/10.1111/ajt.16096. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.info:eu-repo/semantics/articlehttp://dx.doi.org/10.1111/ajt.16096Clinical research/practiceInfection and infectious agents - viralKidney transplantation/nephrologyPatient survivalinfo:eu-repo/semantics/openAccess