Mak, ArthurLee, SueSampson, Nancy A.Albor, YesicaAlonso Caballero, JordiAuerbach, Randy P.Baumeister, HaraldBenjet, CorinaBruffaerts, RonnyCuijpers, PimEbert, David DanielGutierrez-Garcia, Raúl A.Hasking, PenelopeLapsley, CoralLochner, ChristineKessler, Ronald C.2023-02-012023-02-012022Mak ADP, Lee S, Sampson NA, Albor Y, Alonso J, Auerbach RP, Baumeister H, Benjet C, Bruffaerts R, Cuijpers P, Ebert DD, Gutierrez-Garcia RA, Hasking P, Lapsley C, Lochner C, Kessler RC. ADHD comorbidity structure and impairment: results of the WHO World Mental Health Surveys International College Student Project (WMH-ICS). J Atten Disord. 2022 Jun;26(8):1078-96. DOI: 10.1177/108705472110572751087-0547http://hdl.handle.net/10230/55510Objective: To examine the prevalence of ADHD and the association of comorbid disorders, and multivariate disorder classes with role impairment in college students. Method: About 15,991 freshmen (24 colleges, 9 countries, WMH-ICS) (response rate = 45.6%) completed online WMH-CIDI-SC surveys for 6-month ADHD and six 12-month DSM-IV disorders. We examined multivariate disorder classes using latent class analysis (LCA) and simulated a population attributable risk proportions (PARPs) of ADHD-related impairment. Results: About 15.9% had ADHD, of which 58.4% had comorbidities. LCA classified ADHD respondents to pure (42.9%), internalizing (36.0%), bipolar comorbidities (11.3%), and externalizing disorder classes (9.8%). ADHD, comorbidities, and multivariate disorder classes independently predicted severe impairment. PARPs: eliminating ADHD hypothetically reduced severe impairment by 19.2%, 10.1% adjusted for comorbidities, 9.5% for multivariate disorder classes. Conclusions: ADHD and comorbid disorders are common and impairing in college students. Personalized transdiagnostic interventions guided by multivariate disorder classes should be explored.application/pdfengMak ADP, Lee S, Sampson NA, Albor Y, Alonso J, Auerbach RP, Baumeister H, Benjet C, Bruffaerts R, Cuijpers P, Ebert DD, Gutierrez-Garcia RA, Hasking P, Lapsley C, Lochner C, Kessler RC. ADHD comorbidity structure and impairment: results of the WHO World Mental Health Surveys International College Student Project (WMH-ICS). J Atten Disord. 2022 Jun;26(8):1078-96. DOI: 10.1177/10870547211057275. Copyright © The Author(s) 2021. DOI: 10.1177/10870547211057275.info:eu-repo/semantics/articlehttp://dx.doi.org/10.1177/10870547211057275ADHDCollege studentsEpidemiologyMental disorderRole impairmentinfo:eu-repo/semantics/openAccess