Pusceddu, ClaudioVergantino, ElvaSantucci, DomizianaMarsico, SalvatoreCappucci, MatteoVaccarino, FedericaBeomonte Zobel, BrunoGrasso, Rosario FrancescoFaiella, Eliodoro2024-10-242024-10-242023Pusceddu C, Vergantino E, Santucci D, Marsico S, Cappucci M, Vaccarino F, et al. Percutaneous cryoablation under conscious sedation: A safe, effective and painless option for the treatment of pediatric osteoid osteoma. J Clin Med. 2023 Nov 1;12(21):6889. DOI: 10.3390/jcm122168892077-0383http://hdl.handle.net/10230/68330Background: Percutaneous CT-guided cryoablation is an emerging technique for treating bone tumors. However, experience with using this procedure for osteoid osteomas in pediatric patients remains limited. Our study aims to assess its technical feasibility, clinical efficacy, and safety in children treated under conscious anesthesia. Methods: We conducted a retrospective study of consecutive pediatric patients who underwent CT-guided percutaneous cryoablation for osteoid osteomas at our institution between September 2017 and March 2021. All patients received conscious anesthesia. Data on peri-procedural VAS scores, post-procedural VAS scores, imaging findings, and nonsteroidal anti-inflammatory drug (NSAID) usage rates were collected for each patient. Technical success was defined as proper cryoprobe placement at the nidus center, while clinical success referred to pain relief without NSAID use. Intra- and post-operative complications were also evaluated. Results: Nine patients underwent CT-guided percutaneous cryoablation for osteoid osteomas under conscious sedation, with a 100% overall success rate with low peri-procedural and median VAS scores (p < 0.01). No complications were observed during or after the procedure. Conclusions: CT-guided percutaneous cryoablation of pediatric osteoid osteomas is an effective and safe minimally invasive procedure feasible under conscious anesthesia, holding promise as a valuable treatment option.application/pdfeng© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).info:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/jcm12216889Conscious sedationCryoablationInterventional radiologyOsteoid osteomaPediatric patientsPercutaneous treatmentinfo:eu-repo/semantics/openAccess