Thurston, George D.Kipen, HowardAnnesi-Maesano, IsabellaBalmes, JohnBrook, Robert D.Cromar, KevinDe Matteis, SaraForastiere, FrancescoForsberg, BertilFrampton, Mark W.Grigg, JonathanHeederik, DickKelly, FrankKuenzli, NinoLaumbach, RobertPeters, AnnetteRajagopalan, Sanjay T.Rich, DavidRitz, BeateSamet, Jonathan M.Sandstrom, ThomasSigsgaard, TorbenSunyer Deu, JordiBrunekreef, Bert2018-11-272018-11-272017Thurston GD, Kipen H, Annesi-Maesano I, Balmes J, Brook RD, Cromar K et al. A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework. Eur Respir J. 2017 Jan 11;49(1):1600419. DOI: 10.1183/13993003.00419-20160903-1936http://hdl.handle.net/10230/35853The American Thoracic Society has previously published statements on what constitutes an adverse effect on health of air pollution in 1985 and 2000. We set out to update and broaden these past statements that focused primarily on effects on the respiratory system. Since then, many studies have documented effects of air pollution on other organ systems, such as on the cardiovascular and central nervous systems. In addition, many new biomarkers of effects have been developed and applied in air pollution studies.This current report seeks to integrate the latest science into a general framework for interpreting the adversity of the human health effects of air pollution. Rather than trying to provide a catalogue of what is and what is not an adverse effect of air pollution, we propose a set of considerations that can be applied in forming judgments of the adversity of not only currently documented, but also emerging and future effects of air pollution on human health. These considerations are illustrated by the inclusion of examples for different types of health effects of air pollution.application/pdfengThis is an author-submitted, peer-reviewed version of a manuscript that has been accepted for publication in the European Respiratory Journal, prior to copy-editing, formatting and typesetting. This version of the manuscript may not be duplicated or reproduced without prior permission from the copyright owner, the European Respiratory Society. The publisher is not responsible or liable for any errors or omissions in this version of the manuscript or in any version derived from it by any other parties. The final, copy-edited, published article, which is the version of record, is available at http://dx.doi.org/10.1183/13993003.00419-2016Aire -- ContaminacióMedi ambientSalutinfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1183/13993003.00419-2016info:eu-repo/semantics/openAccess