Nadal Clanchet, Eulàlia dePosas Garriga, Francesc2016-02-012016-02-012015de Nadal E, Posas F. Osmostress-induced gene expression--a model to understand how stress-activated protein kinases (SAPKs) regulate transcription. FEBS Journal. 2015; 282(17): 3275-3285. DOI 10.1111/febs.133231742-464Xhttp://hdl.handle.net/10230/25711Adaptation is essential for maximizing cell survival and for cell fitness in response to sudden changes in the environment. Several aspects of cell physiology change during adaptation. Major changes in gene expression are associated with cell exposure to environmental changes, and several aspects of mRNA biogenesis appear to be targeted by signaling pathways upon stress. Exhaustive reviews have been written regarding adaptation to stress and regulation of gene expression. In this review, using osmostress in yeast as a prototypical case study, we highlight those aspects of regulation of gene induction that are general to various environmental stresses as well as mechanistic aspects that are potentially conserved from yeast to mammals.application/pdfeng© 2015 The Authors. FEBS Journal published by John Wiley & Sons Ltd on behalf of FEBS. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.Cèl·lulesProteïnes quinasesinfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1111/febs.13323Gene expressionHog1MammalsOsmostressp38SAPKStress responsesYeastinfo:eu-repo/semantics/openAccess